[1]黄志略,蒙燕萍,陈荟民,等.加味柴黄汤治疗湿热下注型高危人乳头瘤状病毒感染临床研究*[J].陕西中医,2018,(10):1330-1332.
　Huang Zhilue,Meng Yanping,Chen Yuanmin,et al.Clinical study on Jiawei Chaihuang decoction in treating high risk human papillomavirus infection with downward flow of dampness-heat type[J].,2018,(10):1330-1332.
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加味柴黄汤治疗湿热下注型高危人乳头瘤状病毒感染临床研究*
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2018年10期
页码:
1330-1332
栏目:
临床研究
出版日期:
2018-12-31

文章信息/Info

Title:
Clinical study on Jiawei Chaihuang decoction in treating high risk human papillomavirus infection with downward flow of dampness-heat type
文章编号:
DOI: 10.3969/j.issn.1000-7369.2018.10.003
作者:
黄志略; 蒙燕萍; 陈荟民;  夏卫红;  彭莉涯; 杨朝明; 黄莉莉;  张丽君
广西壮族自治区防城港市中医医院（防城港 538021）
Author(s):
Huang Zhilue; Meng Yanping; Chen Yuanmin; et al.
Guangxi Zhuang Autonomous Region Fangchenggang Hospital of Traditional Chinese Medicine ( Fangchenggang 538021)
关键词:
腺病毒; 人@加味柴黄汤湿热下注
Keywords:
Key words Adenoviruses; human@Jiawei Chaihuang decoctionDownward flow of dampness-heat
分类号:
R511
文献标志码:
A
摘要:
摘要 目的：探讨加味柴黄汤治疗高危人乳头瘤状病毒感染湿热下注型的临床效果。方法：选取高危人乳头瘤状病毒感染湿热下注型患者200例。随机分为治疗组与对照组。对照组给予保妇康栓进行治疗。治疗组应用加味柴黄汤治疗。结果：治疗组治疗有效率为90.00%。对照组治疗有效率为66.00%。治疗组治疗有效率明显高于对照组，差异有统计学意义（P＜0.05）。治疗后，治疗组中医证候积分为（8.34±2.42）分。对照组中医证候积分为（11.64±3.12）分。治疗组改善明显优于对照组，差异有统计学意义（P＜0.05）。治疗后，治疗组TNF-α为（7.24±0.39）pg/ml。对照组TNF-α（7.61±0.42）pg/ml。治疗组TNF-α改善明显优于对照组，差异有统计学意义（P＜0.05）。治疗后，治疗组HPV转阴率为81.25%。对照组HPV转阴率为53.75%。治疗组HPV转阴率明显高于对照组，差异有统计学意义（P＜0.05）。治疗组轻度腹泻，发生率为5.00%。对照组轻度腹泻，发生率为2.50%。停药后消失。两组不良反应差异无统计学意义（P＞0.05）。结论：加味柴黄汤治疗高危人乳头瘤状病毒感染湿热下注型的临床效果显著，HPV转阴率高。
Abstract:
Abstract Objective: To explore the clinical effect of Jiawei Chaihuang decoction in the treatment of high-risk human papillomavirus infection with downward flow of dampness-heat type. Methods: Forty patients with high-risk human papillomavirus infection were randomly divided into treatment group and control group. The control group was given Baofu Kang suppository for treatment. The treatment group was treated with Jiawei Chaihuang decoction. Results: The effective rate of treatment in the treatment group was 90.00%, the control group was 66.00%. The effective rate of the treatment group was significantly higher than the control group，the difference was statistically significant (P＜0.05). After treatment，the treatment group of TCM syndrome points (8.34±2.42) points. The TCM syndrome score in the control group was (11.64±3.12) points. The improvement of the treatment group was significantly better than the control group，the difference was statistically significant (P＜0.05). After treatment，TNF-α in the treatment group was (7.24±0.39) pg / ml. TNF-α (7.61±0.42) pg / ml in the control group. The improvement of TNF-α in the treatment group was better than that in the control group，the difference was statistically significant (P＜0.05). The treatment group HPV negative rate was 81.25%. In the control group，the negative rate was 53.75%. Treatment group HPV negative rate was significantly higher than the control group. The difference was statistically significant (P＜0.05). Treatment group showed mild diarrhea incidence was 5.00%. The control group showed mild diarrhea incidence was 2.50%. After the withdrawal disappeared. There was no significant difference between the two groups (P＞ 0.05). Conclusion: The effect of Jiawei Chaihuang decoction on the treatment of high risk human papillomavirus infection is significant，and HPV has a high negative rate.

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备注/Memo

备注/Memo:
*广西壮族自治区中医药民族医药传承创新项目(GZLC16-76)
更新日期/Last Update: 2019-01-07