[1]刘欢,周建忠,王苗,等.针刺治疗中风后手指过屈疗效及对患者中医症候积分 与关节功能相关指标的影响*[J].陕西中医,2018,(10):1466-1469.
 Liu Huan,Zhou Jianzhong,Wang Miao,et al.The efficacy of acupuncture in the treatment of finger hyperflexion after stroke and the effect on the TCM syndrome scores and joint function associated indexes[J].,2018,(10):1466-1469.
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针刺治疗中风后手指过屈疗效及对患者中医症候积分 与关节功能相关指标的影响*

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2018年10期
页码:
1466-1469
栏目:
针灸经络
出版日期:
2018-12-31

文章信息/Info

Title:
The efficacy of acupuncture in the treatment of finger hyperflexion after stroke and the effect on the TCM syndrome scores and joint function associated indexes
文章编号:
DOI: 10.3969/j.issn.1000-7369.2018.10.048
作者:
刘欢1周建忠2王苗1汪秀梅1周钰1△
1.新疆医科大学第一附属医院针灸推拿科(乌鲁木齐830000), 2.新疆医科大学第一附属医院昌吉分院针灸推拿科(昌吉831100)
Author(s):
Liu HuanZhou JianzhongWang Miaoet al.
Department of Acupuncture and Moxibustion, First Affiliated Hospital of Xinjiang Medical University (Urumqi 830054)
关键词:
中风/针刺疗法穴水沟穴内关穴曲池
Keywords:
Key words Poststroke syndrome/acupuncture therapyPoint GV26(Shuigou)Point PC6(Neiguan)Point LI11(Quchi)
分类号:
R255.2
文献标志码:
A
摘要:
摘要 目的:观察针刺治疗中风后手指过屈的疗效及对患者中医症候积分与关节功能相关指标的影响。方法:将60例中风后手指过屈患者随机分为针刺治疗组(30例)和巴氯芬治疗组(30例),治疗30d后,观察两组患者治疗效果,治疗前后中医证候积分、手指痉挛程度、神经功能缺损评分(NISS)、中医侯症积分和掌指关节活动度变化情况及检测两组患者治疗前后cAMP、cGMP、IP3、DAG水平。结果: 针刺组患者治疗总有效率(86.67%)显著高于巴氯芬组(56.67%)(P<0.05),针刺组患者在治疗15 d和30 d后手指痉挛改善程度和掌指关节活动度显著优于巴氯芬组(P<0.05);治疗后针刺治疗组患者NISS评分和中医证候积分较巴氯芬药物组改善更明显,差异具有统计学意义(P<0.05)。与巴氯芬药物组比较,治疗后针刺组患者cAMP含量显著增加,而cGMP、IP3和DAG含量明显降低,差异具有统计学意义(P<0.05)。结论:针刺治疗中风后手指过屈有显著改善作用,能够提高cAMP水平和降低cGMP、IP3、DAG水平,介导Ca2+超载,降低肌肉张力,促进手指关节功能恢复。
Abstract:
Abstract Objective:To observe the efficacy of acupuncture in the treatment of finger hyperflexion after stroke and the effect on TCM syndrome scores and joint function associated indexes. Methods:Sixty patients with finger hyperflexion after stroke were randomly divided into the acupuncture treatment group (30 cases) and baclofen treatment group (30 cases). After 30 days of treatment,the treatment effects,TCM syndrome scores,degree of finger spasm,neurological impairment scores (NISS) and metacarpophalangeal joint activity before and after treatment were observed,and the levels of cAMP,cGMP,IP3 and DAG were detected. Results:The total effective rate of treatment in the acupuncture treatment group (86.67%) was significantly higher than that in the baclofen treatment group (56.67%) (P<0.05). After 15 d and 30 d of treatment,the relief of finger spasm and improvement of metacarpophalangeal joint activity in the acupuncture treatment group were more significant than those in the baclofen treatment group (P<0.05). After the treatment,the improvement of NISS score and TCM symptom scores in the acupuncture treatment group were more significant than those in the baclofen treatment group (P<0.05). Compared with the baclofen treatment group,cAMP level in the acupuncture treatment group increased significantly after treatment while the levels of cGMP,IP3 and DAG decreased significantly (P<0.05). Conclusion:Acupuncture is effective in the treatment of finger hyperflexation after stroke. It can improve the cAMP level and reduce the levels of cGMP,IP3 and DAG,mediate Ca2+ overload,reduce muscle tension,and promote the recovery of joint function.

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备注/Memo

备注/Memo:
*新疆维吾尔自治区自然科学基金资助项目(2016D0113009)
更新日期/Last Update: 2019-01-07