[1]贾勇,赵金秀,杨朝红.正交试验法筛选慢粒灵胶囊成型工艺*[J].陕西中医,2018,(10):1476-1478,1482.
 Jia Yong,Zhao Jinxiu,Yang Chaohong..Study on molding technics of Manliling capsule[J].,2018,(10):1476-1478,1482.
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正交试验法筛选慢粒灵胶囊成型工艺*
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2018年10期
页码:
1476-1478,1482
栏目:
方药纵横
出版日期:
2018-12-31

文章信息/Info

Title:
Study on molding technics of Manliling capsule
文章编号:
DOI: 10.3969/j.issn.1000-7369.2018.10.051
作者:
贾勇赵金秀杨朝红
河北省廊坊市中医院制剂室 (廊坊065000)
Author(s):
Jia YongZhao JinxiuYang Chaohong.
Dispensing Room,LangfangTCM Hospital of Hebei province(Langfang 065000)
关键词:
正交试验@慢粒灵胶囊中药工艺改进
Keywords:
Key words Orthogonal test @Manliling capsuleTechnology Improving
分类号:
R94
文献标志码:
A
摘要:
摘要 目的:优选慢粒灵胶囊的成型工艺。方法:考察不同辅料对浸膏粉吸湿性、休止角的影响,采用正交试验法,以崩解时间和吸湿率为指标,考察填充剂和助流剂,清膏的相对密度,湿润剂的浓度,加入的方法。结果:成型的最佳工艺为浸膏密度为1.25,用糊精做填充剂和助流剂,用搅拌机混匀,润湿剂乙醇的浓度为55%。结论:该成型工艺合理可行,适合中试生产需要。
Abstract:
Abstract Objective:To study the formation technology of Manliling capsule. Methods:The influence of different excipients on the hygroscopicity of extract powder was investigated . The orthogonal test was performed with the index of puerarin,with the disintegration time and the moisture absorption as indexes,orthogonal test was used to investigate factors of wetting agent concentration,method of joining. Results:The density of cream was 1.25,the filler and flow aiding agent was dextrin,the wetting agent concentration was 55%,the join method was stired with bleneder. Conclusion:The optimized extraction and purification technology for Manliling capsule is reasonable,The forming process is reasonable and feasible,which is suitable for pilot production

参考文献/References:


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备注/Memo

备注/Memo:
*河北省廊坊市科学技术与发展规划自筹经费项目(2012013018)
更新日期/Last Update: 2019-01-07