[1]卢红治,王倩,党东.补肾活血汤对缺血性脑卒中疗效及对患者神经功能、生活质量的影响*[J].陕西中医,2018,(11):1524-1526.
　Lu Hongzhi,Wang Qian.Department of Encephalopathy,The First Hospital of Traditional.The effect of Bushen Huoxue decoction on the efficacy and neurological function, quality of life and ability of patients with ischemic stroke[J].,2018,(11):1524-1526.
点击复制

补肾活血汤对缺血性脑卒中疗效及对患者神经功能、生活质量的影响*
分享到：

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2018年11期
页码:
1524-1526
栏目:
临床研究
出版日期:
2018-12-31

文章信息/Info

Title:
The effect of Bushen Huoxue decoction on the efficacy and neurological function, quality of life and ability of patients with ischemic stroke
文章编号:
10.3969/j.issn.1000-7369.2018.11.010
作者:
卢红治1; 王倩2; 党东3
1. 河南省洛阳市第一中医院脑病科（洛阳 471000），2. 河南省漯河市中心医院神经内科（漯河 462000）,3.陕西省榆林市中医院（榆林719000）
Author(s):
Lu Hongzhi; Wang Qian.Department of Encephalopathy;  The First Hospital of Traditional
Chinese Medicine in Luoyang(Luoyang 471000)
关键词:
卒中/中医药疗法@补肾活血汤
Keywords:
Stroke/traditionalChinese medicine therapy@Bushen Huoxue decoction
分类号:
R743.3
文献标志码:
A
摘要:
目的： 探讨补肾活血汤对于缺血性脑卒中患者的疗效与神经功能、生活质量与能力的影响。方法：选取缺血性脑卒中患者92例，按照随机数字表法，分为观察组和对照组各46例，两组均给予控制血压、血糖和降颅内压等常规治疗，对照组使用阿司匹林肠溶片进行治疗，观察组患者在此基础上使用补肾活血汤进行联合治疗，观察两组临床疗效、神经功能缺损评分、生活能力、治疗后生活质量评分，对患者凝血功能指标进行比较。结果：观察组总有效率明显高于对照组（P<0.05）；治疗前，两组患者神经功能缺损评分和生活能力评分无明显差异（P>0.05）；治疗后，观察组神经功能缺损评分降低程度、生活能力评分升高程度更加明显（P<0.05）；治疗前，两组患者血小板聚集率、纤维蛋白原、全血黏度、血浆黏度无明显差异（P>0.05）；治疗后，两组血液流变学指标均有所改善，且观察组纤维蛋白原、全血黏度降低程度更加明显，差异有统计学意义（P<0.05）；观察组患者在生活质量各方面评分均优于对照组（P<0.05）。结论：补肾活血汤可明显提高缺血性脑卒中患者疗效，促进患者神经功能恢复，改善凝血功能。
Abstract:
Objective : Explore the effect of Bushen Huoxue decoction on the efficacy and neurological function, quality of life and ability of patients with ischemic stroke. Methods :Choose 92 cases of ischemic cerebral apoplexy patients, according to the stochastic indicator method, randomly divided into observation group and control group, each 46 cases .two groups were given control of blood pressure, blood sugar and lower intracranial pressure, such as conventional treatment, the control group using aspirin enteric-coated metformin hydrochloride treatment, observation group of patients on the basis of using Bushen Huoxue decoction for combination therapy, comparing two groups of clinical curative effect, and the two set of neural function defect scale and life ability score comparison, observe the quality of life scores after treatment in both groups, compared to blood coagulation function in patients with indexes. Results: The total effective rate of the observation group was 86.96%, the control group was 65.22% (P<0.05). Before treatment, there was no statistically significant difference between the scores of neurological deficits and the life ability score of the two groups (P>0.05). After treatment, the scores of both groups were improved, and the scores of neurological function defects and life ability score increased significantly in the observation group (P<0.05). Before treatment, there was no significant difference in platelet aggregation rate, fibrinogen, whole blood viscosity and plasma viscosity in the two groups (P>0.05). After treatment, both groups of hemorheological indexes improved, and the degree of reduction of fibrinogen and whole blood viscosity was more obvious in the observation group (P<0.05). Observation group of patients in the physiological function, physiological functions, physical pain, general health, vitality, social function, emotional function, mental health scores were better than that in control group (P<0.05). Conclusion :The effect of Bushen Huoxue decoction can obviously improve the curative effect of patients with ischemic stroke, promote the recovery of patients' neurological function, improve the quality of life of patients, improve coagulation function, and deserve further promotion.

参考文献/References:

[1]杨成,金剑虹,唐成坤,等.自身免疫性甲状腺炎中西医研究进展[J].浙江中西医结合杂志,2018,28(4):335-338.
[2]〖JP4〗叶玉峰, 江潮, 邵迎新,等. 益气化瘀法在自身免疫性甲状腺疾病中的应用[J]. 中国医药导报, 2016, 13(10):80-83.
[3]石元同, 张思德. 夏枯草胶囊联合优甲乐治疗桥本甲状腺炎临床疗效[J]. 陕西中医, 2017, 38(11):1562-1563.
[4] 郑建洵. 甲状腺自身抗体在自身免疫性甲状腺疾病诊断中的临床应用[J]. 标记免疫分析与临床, 2016, 23(12):1427-1429.
[5] 段素静, 谌剑飞, 谭薇,等. 自身免疫性甲状腺疾病肾上腺皮质功能变化与肾虚证的相关性研究[J]. 中西医结合心脑血管病杂志, 2016, 14(19):2227-2229.
[6]韩雨航. 益气化痰消瘿法对桥本甲状腺炎患者血清甲状腺球蛋白的影响[J]. 中国民间疗法, 2017, 25(2):32-33.
[7]赵庆瑞. 针对性治疗原发性肾病综合征并发急性肾功能衰竭的疗效及对患者生活质量的影响[J]. 临床合理用药杂志, 2016, 9(7):124-125.
[8] 刘欢, 宋守君, 薛海波. 微小RNA在自身免疫性甲状腺疾病发病中的作用[J]. 山东医药, 2016, 56(25):111-113.
[9] 许杨, 王义娜. 糖皮质激素在自身免疫性甲状腺疾病治疗中的选择和应用[J]. 中国实用医药, 2016, 11(10):181-183.
[10] 刘国新, 金剑虹, 洪郁芝. 硒剂治疗自身免疫性甲状腺炎作用机制研究进展[J]. 浙江医学, 2017, 39(14):1230-1232.
[11] 李丹, 史艳平, 耿玲玲,等. 白芍总苷联合海桐皮熏蒸治疗幼年特发性关节炎疗效及炎症因子变化[J]. 陕西中医, 2016, 37(9):1192-1194.
[12]王丹, 赵勇, 左新河. 中医药治疗自身免疫性甲状腺炎的研究进展[J]. 江西中医药, 2016, 47(7):75-77.
[13]侯振江, 牟兆新. 白细胞介素10及其受体在自身免疫性甲状腺疾病中的研究进展[J]. 医学综述, 2016, 22(24):4823-4827.
[14]郑建洵. 甲状腺自身抗体在自身免疫性甲状腺疾病诊断中的临床应用[J]. 标记免疫分析与临床, 2016, 23(12):1427-1429.

备注/Memo

备注/Memo:
*河南省科技攻关重点项目(092102310181)
更新日期/Last Update: 2018-11-30