[1]白宇望,杨利生,魏光明△ .小柴胡汤加减方治疗上呼吸道感染发热临床研究[J].陕西中医,2019,(2):223-225,240.
　BAI Yuwang,YANG Lisheng,WEI Guangming..Observationon curative effect of Xiaochaihu decoction in treating fever caused by upper respiratory tract infection[J].,2019,(2):223-225,240.
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小柴胡汤加减方治疗上呼吸道感染发热临床研究
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2019年2期
页码:
223-225,240
栏目:
临床研究
出版日期:
2019-02-05

文章信息/Info

Title:
Observationon curative effect of Xiaochaihu decoction in treating fever  caused by upper respiratory tract infection
文章编号:
DOI: 10.3969/j.issn.10007369.2019.02.025
作者:
白宇望1; 杨利生1; 魏光明2△ 
1.西安市中医医院肺病科（西安 710016）；2.空军军医大学唐都医院 （西安 710038）
Author(s):
BAI Yuwang; YANG Lisheng; WEI Guangming.
Lung Disease Department of Xi 'an Hospital of Traditional Chinese Medicine (Xi 'an 710016)
关键词:
上呼吸道感染; 发热; 小柴胡汤; 血清反应蛋白; β2微球蛋白; 前白蛋白
Keywords:
Key words Upper respiratory tract infection ;  Fever;  Xiaochaihu decoction ;  CRP; β2MG;  PA
分类号:
R562.2
文献标志码:
A
摘要:
摘 要 目的：探讨小柴胡汤加减方治疗上呼吸道感染发热的治疗效果。方法：选择80例上呼吸道感染发热患者，按照随机数字表法分为观察组和对照组各40例，观察组给予小柴胡汤加减方治疗，对照组给予抗感染，退热治疗。观察比较两组的治疗总有效率，主要症状消失时间，血清反应蛋白（CRP）、β2微球蛋白（β2MG）、前白蛋白（PA）及血沉（ESR）、T淋巴细胞亚群、免疫球蛋白情况。结果：观察组总有效率为97.50%，明显高于对照组（75.00%），差异具有统计学意义（P＜0.05）；观察组发热反复次数（2.36±0.62）次，平均发热时间为（1.24±0.73） d，咽部充血消失时间（2.12±0.24） d，咳嗽消失时间（2.89±0.22） d，流涕停止时间（2.14±0.24） d，咳痰停止时间（2.65±0.59） d，均显著少于对照组各症状消失时间（P＜0.05）；治疗后观察组血清CRP、β2MG、ESR水平明显低于对照组，PA水平明显高于对照组（P＜0.05）；临床症状体征发热、咳嗽、咳痰、鼻塞、纳少等中医证候积分及总积分明显低于对照组（P＜0.05）；T淋巴细胞亚群CD4+、CD3+含量明显高于对照组，CD4+/ CD8+值明显大于对照组，IgG、IgM、IgA明显低于对照组，差异具有统计学意义（P＜0.05）。结论：小柴胡汤加减方治疗上呼吸道感染发热疗效显著，可在短时间内降低患者体温，改善患者症状，提高患者免疫功能。 
Abstract:
Abstract Objective:To investigate the therapeutic effect of Xiaochaihu decoction in treating upper respiratory tract infection fever. Methods:The 80 patients with upper respiratory tract infections were selected and divided into observation group (n=40) and control group (n=40) according to the random number table method. The observation group was treated with Xiaochaihu decoction,the control group was given antiinfection,antipyretic therapy. the total effective rate of treatment,the disappearance time of main symptoms,serum reactive protein (CRP),β2microglobulin (β2MG),prealbumin (PA),ESR,and T lymphocyte subsets,immunoglobulin conditions were observed and compared.Results:The total effective rate in the observation group was 97.50%,which was significantly higher than that in the control group (75.00%),and the difference was statistically significant (P＜0.05). The number of repeated episodes of fever (2.36±0.62) was observed in the observation group. The mean fever time was (1.24±0.73) days,the disappearance time of pharyngeal congestion (2.12±0.24)d,the time of disappearance of cough (2.89±0.22) days,and the time of flow cessation ( 2.14±0.24)d,cough stop time (2.65±0.59)d,both significantly less than the disappearance time of each symptom in the control group (P＜0.05). After treatment,serum CRP,β2MG,and ESR levels in the observation group were significantly lower than those in the control group,the PA level was significantly higher than the control group (P＜0.05).The TCM syndrome scores and total scores such as fever,cough,sputum,nasal congestion,and nausea were significantly lower than those in the control group (P＜0.05). The content of CD4+ and CD3+ in T lymphocyte subsets was significantly higher than that in the control group,the CD4+/CD8+ values were significantly higher than those in the control group,IgG,IgM,and IgA were significantly lower than those in the control group,with a significant difference (P＜0.05).Conclusion: Xiaochaihu decoction is effective in treating upper respiratory tract infections and can reduce the body temperature of patients in a short period of time,improve the symptoms of patients,and improve the immune function of patients. It has certain application value. 

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更新日期/Last Update: 2019-03-13