[1]杨 寒,王 超,张玲燕.益气养阴温心汤联合酒石酸美托洛尔治疗老年冠心病疗效研究*[J].陕西中医,2019,(4):447-449.
 YANG Han,WANG Chao,ZHANG Lingyan..Clinical observation of Yiqi Yangyin Wenxin decoction combined with metoprolol tartrate in the treatment of senile coronary heart disease[J].,2019,(4):447-449.
点击复制

益气养阴温心汤联合酒石酸美托洛尔治疗老年冠心病疗效研究*
分享到:

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2019年4期
页码:
447-449
栏目:
临床研究
出版日期:
2019-04-05

文章信息/Info

Title:
Clinical observation of Yiqi Yangyin Wenxin decoction combined with  metoprolol tartrate in the treatment of senile coronary heart disease
文章编号:
DOI:10.3969/j.issn.10007369.2019.04.012
作者:
杨 寒王 超张玲燕
河南省南阳南石医院老年病科(南阳 473000)
Author(s):
YANG HanWANG ChaoZHANG Lingyan.
Department of Geriatrics, Nanyang Nanshi Hospital in Henan Province(Nanyang 473000)
关键词:
益气养阴温心汤酒石酸美托洛尔老年冠心病早搏血脂疗效比较
Keywords:
Key words Yiqi Yangyin Wenxin decoction Metoprolol tartrate Senile coronary heart disease Early fight Lipid Comparison of curative effects
分类号:
R541.4
文献标志码:
A
摘要:
摘 要 目的:研究益气养阴温心汤联合酒石酸美托洛尔治疗老年冠心病的临床观察。方法:根据随机表法将110例老年冠心病患者分为对照组和治疗组,各55例。对照组采用酒石酸美托洛尔治疗,治疗组在对照组基础上联合应用益气养阴温心汤进行治疗。比较两组患者治疗疗效、室性早搏数、房性早搏数、交界性早搏数、TG、TC、HDLC、LDLC水平、治疗前后心率和QTd的变化。结果:治疗组总有效率为90.91%高于对照组治疗总有效率的60.00% (P<0.05);治疗组患者的室性早搏次数(967.25±395.56)次、房性早搏次数(125.84±47.28)次和交界性早搏次数(153.84±59.29)次明显少于对照组室性早搏次数(1847.54±573.68)次、房性早搏次数(379.73±179.42)次和交界性早搏次数(482.15±164.26)次 (P<0.05)。治疗组患者TG(1.98±0.31)mg/dl、TC(5.36±0.45)mg/dl、LDLC(2.46±0.35)mg/dl低于对照组TG(2.13±0.33)mg/dl、TC(5.63±0.48)mg/dl、LDLC(2.63±0.39)mg/dl, 治疗组HDLC(1.08±0.38)mg/dl高于对照组HDLC(0.93±0.28)mg/dl (P<0.05)。治疗组心率(63.57±7.82)次/min明显减慢于对照组的心率(71.44±8.26)次/min,QTd(42.32±15.14)ms也低于对照组QTd(49.46±15.62) ms (P<0.05)。结论:益气养阴温心汤联合酒石酸美托洛尔疗效显著。
Abstract:
Abstract Objective: To study the clinical observation of Yiqi Yangyin Wenxin decoction combined with metoprolol tartrate in the treatment of senile coronary heart disease. Methods: According to the excel random table method, 110 elderly patients with coronary heart disease were divided into the control group and the treatment group, 55 cases in each group. The control group was treated with metoprolol tartrate, and the treatment group was treated with Yiqi Yangyin Wenxin decoction on the basis of the control group. The therapeutic effects, ventricular premature beats, atrial premature beats, borderline premature beats, TG, TC, HDLC, LDLC levels, heart rate and QTd before and after treatment were compared between the two groups. Results: The results showed that the total effective rate of the treatment group was 90.91% higher than that of the control group (P<0.05). The number of premature ventricular beats (967.25±395.56), the number of atrial premature beats (125.84±47.28) and the number of borderline premature beats (153.84±59.29) in the treatment group were significantly lower than that in the control group (1847.54±573.68), the number of ventricular premature beats (379.73±179.42) and the number of borderline premature beats (482.15±164.26) (P<0.05). TG (1.98 ±0.31) mg/dl, TC (5.36±0.45) mg/dl, ldlc (2.46±0.35) were lower than that of the control group (2.13±0.33) mg/dl, TC (5.63±0.48) mg/dl, ldlc (2.63±0.39) mg/dl, and HDLC (1.08±0.38) mg/dl was higher than that of the control group (0.93±0.28) mg/dl (P<0.05). Heart rate of the treatment group (63.57±7.82) times/min was significantly slowed down in the control group (71.44±8.26) times/min, and QTd (42.32±15.14) ms was also lower than that of the control group (49.46±15.62) ms (P< 0.05).Conclusion:Yiqi Yangyin Wenxin decoction combined with metoprolol tartrate is worthy of clinical promotion.

参考文献/References:

[1] 陈红光,付 鑫,卢 杰.瑞舒伐他汀对老年冠心病合并高脂血症病人血管内皮功能及血浆脑钠肽的影响 [J].实用老年医学,2018,32(8):777780.
[2] 宫敛智.益气养阴汤治疗气阴两虚型老年冠心病疗效观察 [J].中西医结合心血管病杂志,2018,6(11): 132133.
[3] 刘伟昌.瑞舒伐他汀与辛伐他汀治疗老年冠心病的疗效及对患者血脂水平影响的比较 [J].临床合理用药杂志,2018,11(16):6466.
[4] 李伟玲.阿司匹林联合替罗非班预防冠心病 PCI 术后血栓形成100例分析 [J].陕西医学杂志,2017,46(1):112114.
[5] 焦春发,杜俊宝,曹柏龙.中药制剂联合西医治疗不同中医证型冠心病心绞痛疗效观察 [J].陕西中医,2017,38(1):2223.
[6] 陈学彬,宁小康.麝香保心丸对老年冠心病合并颈动脉粥样硬化斑块患者血清hsCRP、VEGF、MMP9水平及血脂的影响 [J].陕西中医,2017,38(4):427429.
[7] 王 超,白 敏,陈 磊.丹参注射液联合酒石酸美托洛尔治疗老年冠状动脉粥样硬化性心脏病临床评价 [J].中华中医药学刊,2018,36(3): 700702.
[8] 王艳丽.中药复方汤剂联合辛伐他汀治疗老年冠心病的疗效及对心肌灌注量的影响 [J].四川中医,2017,35(3):8587.
[9] 李松柏.中医益气养阴活血法治疗冠心病并频发室性早搏46例临床观察 [J].中国现代药物应用,2017,11(7):186188.〖ZK)〗
[10] 王宏志, 赵 敏, 李亚蒙,等.丹红注射液联合酒石酸美托洛尔对冠心病心律失常患者血流动力学及心电图的影响 [J].心血管康复医学杂志,2018,27(3):355360.
[11] 齐 欣,郭书文,陈剑明,等.益气活血法联合酒石酸美托洛尔治疗冠心病心律失常的临床研究 [J].中华中医药学刊,2017, 35(2): 279282.
[12] 李 玲.加味生脉散联合西药治疗气阴两虚型冠心病合并高血脂疗效观察 [J].陕西中医,2017,38(12):16431645.

备注/Memo

备注/Memo:
*河南省科技攻关重点项目(81674017)
更新日期/Last Update: 2019-04-24