[1]高 扬,耿 鹏,郭书娟,等.加味大承气汤辅助腹腔镜胆囊切除术治疗结石性胆囊炎 疗效及对患者消化功能的影响*[J].陕西中医,2019,(4):493-495.
　GAO Yang,GENG Peng,GUO Shujuan,et al.Effect of Jiawei dachengqi decoction assisted laparoscopic cholecystectomy on digestive function of patients with calculous cholecystitis[J].,2019,(4):493-495.
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加味大承气汤辅助腹腔镜胆囊切除术治疗结石性胆囊炎 疗效及对患者消化功能的影响*
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2019年4期
页码:
493-495
栏目:
临床研究
出版日期:
2019-04-05

文章信息/Info

Title:
Effect of Jiawei dachengqi decoction assisted laparoscopic  cholecystectomy on digestive function of patients with calculous cholecystitis
文章编号:
DOI:10.3969/j.issn.10007369.2019.04.027
作者:
高 扬; 耿 鹏; 郭书娟; 程 如; 宋同庆; 李本心
河南省漯河市中医院外一科(漯河462000)
Author(s):
GAO Yang; GENG Peng; GUO Shujuan; et al.
Department of External Medicine，Luohe Hospital of Traditional in Henan Province（ Luohe 462000）
关键词:
结石性胆囊炎; 加味大承气汤; 腹腔镜; 胆囊切除术; 消化功能指标; 不良反应; 血浆胃泌素
Keywords:
Key words Calculous cholecystitis; Jiawei Dachengqi decoction; Laparoscopy; Cholecystectomy; Digestive function index; Adverse reactions; Plasma gastrin
分类号:
R657.41
文献标志码:
A
摘要:
摘 要 目的：探讨加味大承气汤在腹腔镜胆囊切除术治疗结石性胆囊炎患者中辅助应用后对患者消化功能指标及术后指标的影响。方法：选择124例结石性胆囊炎并行胆囊切除术的患者，将患者分为对照组与观察组，每组62例。两组患者均性腹腔镜胆囊切除术，术后对照组患者采用常规治疗方式，观察组患者采用加味大承气汤治疗，7 d为1个疗程，连续治疗4个疗程。观察两组患者术后功能指标的恢复情况，血浆胃泌素（MOT）、血管活性肠肽（VIP）和生长抑素（SS）水平变化及不良反应发生率的变化情况。结果：①治疗后观察组患者的功能指标排气时间、进食时间、肠鸣缓解时间、腹胀缓解时间与对照组患者比较均明显缩短，数据比较差异具有统计学意义（P＜0.05）；②治疗后观察组患者消化功能指标MOT为（174.70±9.13）ng/L、VIP（12.81±2.61）ng/L 、SS（14.22±2.60）ng/L，对照组治疗后MOT为（139.19±9.68）ng/L、VIP值为（18.80±2.94）ng/L、SS值为（10.47±2.23）ng/L，两组各项比值差异均有统计学意义（P均＜0.05）；③观察组不良反应发生率为3.23%，对照组不良反应发生率为11.29%，比较差异具有统计学意义（P＜0.05）。结论：加味大承气汤辅助用于经腹腔镜胆囊切除术治疗结石性胆囊炎患者中，可以增强患者活血化瘀，疏通血液循环，缩短患者术后各项功能指标的恢复时间，改善患者的各项消化功能指标，增加患者的食欲，促进患者早日康复，且副作用小。
Abstract:
Abstract Objective：To investigate the effect of Jiawei Dachengqi decoction on the digestive function index and postoperative indexes in patients with calculus cholecystitis treated with laparoscopic cholecystectomy. Methods：A total of 124 patients with gallstone cholecystitis and cholecystectomy admitted were divided into control group and observation group，and 62 cases in each group. The patients in the two groups were taken with laparoscopic cholecystectomy. The patients in the control group were treated with conventional treatment. The patients in the observation group were treated with Dachengqi decoction. 7 days were as a course of treatment，and treated for 4 courses of continuous treatment. The recovery of postoperative functional indexes，MOT，VIP and SS levels and the incidence of adverse reactions were observed. Results：①After treatment，the functional index of the patients in the observation group，the time of exhaustion，the time of eating，the time of bowel remission，and the time of remission of abdominal distension were significantly shorter than those of the control group. The differences of the data were with statistical significance (P＜0.05). ② The MOT，VIP，SS the differences between the two groups were with statistical significance (P＜0.05). ③ After treatment，the incidence of adverse reactions was 3.23% in the observation group.2 patients were with abdominal pain，the incidence of adverse reactions was 11.29%. The differences were with statistical significance(P＜0.05). Conclusion:Jiawei Dachengqi decoction can be used in the treatment of patients with calculous cholecystitis by laparoscopic cholecystectomy，which can enhance the blood circulation of patients，clear the blood circulation of patients，shorten the recovery time of various functional indexes after surgery，and improve the digestive function indicators and increase the appetite of the patient，promote the patient's early recovery，and have fewer side effects.

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备注/Memo

备注/Memo:
*河南省中医药科学研究专项课题(2016ZY02389)
更新日期/Last Update: 2019-04-24