[1]要 静,王利平,张红霞.清热理血汤治疗盆腔炎后遗症疗效及对患者血清粒-巨噬细胞集落刺激因子、白细胞介素-2、血流变学的影响*[J].陕西中医,2019,(6):746-748.
 YAO Jing,WANG Liping,ZHANG Hongxia..Effect of Qingre Lixue decoction on serum GM-CSF,IL-2 and hemorheology in patients with pelvic sequelae[J].,2019,(6):746-748.
点击复制

清热理血汤治疗盆腔炎后遗症疗效及对患者血清粒-巨噬细胞集落刺激因子、白细胞介素-2、血流变学的影响*
分享到:

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2019年6期
页码:
746-748
栏目:
临床研究
出版日期:
2019-06-05

文章信息/Info

Title:
Effect of Qingre Lixue decoction on serum GM-CSF,IL-2 and hemorheology in patients with pelvic sequelae
文章编号:
DOI:10.3969/j.issn.1000-7369.2019.06.018
作者:
要 静1王利平1张红霞
1.河南省开封市中医院妇科(开封475000);2.河南大学淮河医院妇产科(开封475000)
Author(s):
YAO JingWANG LipingZHANG Hongxia.
Department of Gynecology, Kaifeng Traditional Chinese Medicine Hospital in Henan Province(Kaifeng 475000)
关键词:
清热理血汤盆腔炎后遗症GM-CSFIL-2血流流变学临床疗效
Keywords:
Key words Qingre Lixue decoctionPelvic sequelaeGM-CSFIL-2HemorheologyClinical efficacy
分类号:
R711.33
文献标志码:
A
摘要:
摘 要 目的:探究清热理血汤对盆腔炎后遗症患者的临床疗效。方法:选取87例盆腔炎后遗症患者作为研究对象,按照随机数字法分为对照组42例给予康妇炎胶囊进行治疗;观察组45例给予清热理血汤进行治疗。结果:治疗后观察组临床总有效率93.33%显著高于对照组78.57%,观察组中医证候积分、GM-CSF、全血高切、全血中切、全血低切、血浆黏度、血沉率水平降低水平更为显著,血清IL-2上升水平更为显著,差异具有统计学意义( P <0.05)。 结论:清热理血汤能有效改善患者临床症状及中医证候,增强患者免疫功能,有效抑制炎症反应,促进血液微循环。
Abstract:
Abstract Objective:To investigate the clinical effect of Qingre Lixue decoction in patients with pelvic sequelae.Methods:87 patients with pelvic sequelae admitted were divided into the control group 42 cases,Kangfuyan capsule and the observation group 45 cases,Qingre Lixue decoction according to the random number method.The clinical efficiency of the two groups and its effects on TCM syndrome scores,serum GM-CSF,serum IL-2 and hemorheology were observed.Results:After treatment,the total effective rate of the observation group was significantly higher than that of the control group (93.33% vs.78.57%).The TCM syndrome score,GM-CSF,all the values of whole blood viscosity,plasma viscosity,and erythrocyte sedimentation rate were significantly decreased in the observation group,while the serum IL-2 level was significant increased ( P <0.05).Conclusions:Qingre Lixue decoction can effectively improve the clinical symptoms and TCM syndromes,enhance the immune function in patients,and effectively inhibit the inflammatory response,promoting blood microcirculation.

参考文献/References:

[1] 符泽美,李丽娟,王爱丽.加味少腹逐瘀汤治疗盆腔炎性疾病后遗症-慢性盆腔痛寒湿凝滞证的临床分析[J].中国实验方剂学杂志,2018,26(10):892-893.
[2]Kreisel K,Flagg EW,Torrone E.Trends in pelvic inflammatory disease emergency department visits,United States,2006–2013[J].American Journal of Obstetrics & Gynecology,2017,218(1):3524-3525
[3] 梁 照,许 琳,金 哲.丹枝饮对气滞血瘀型盆腔炎性疾病后遗症-慢性盆腔痛的临床疗效观察[J].中国中医基础医学杂志,2017,20(4):518-520.
[4] Park ST,Lee SW,Min JK, et al .Clinical characteristics of genital chlamydia infection in pelvic inflammatory disease[J].Bmc Womens Health,2017,17(1):5-6
[5] 尹小兰,魏绍斌.盆腔炎性疾病后遗症疗效评价方法的应用现状分析[J].中华中医药杂志,2016,67(10):4132-4134.
[6] 刘元姣.新编妇产科疾病诊疗学\[M\].北京:人民卫生出版社,2002:52-53
[7] 张玉珍.新编中医妇科学\[M\].北京:人民军医出版社,2001:77-78
[8] 国家中医药管理局.中药新药临床研究指导原则(试行)\[M\].北京:中国医药科技出版社,2002:124-125
[9] Zou W,Wen X,Sheng X, et al .Gas chromatography-mass spectrometric method-based urine metabolomic profile of rats with pelvic inflammatory disease[J].Experimental & Therapeutic Medicine,2016,11(5):1653-1660.〖ZK)〗
[10] Tia O,Odewale MA.Socioeconomic status of parents and the occurrence of pelvic inflammatory disease among undergraduates attending irrua specialist teaching hospital,irrua,edo state,nigeria[J].Nigerian Postgraduate Medical Journal,2017,24(2):114.
[11] 刘彤鸥,王加谋,王师菡.化瘀固本方对慢性盆腔炎大鼠相关细胞因子及血液流变学的影响[J].中药材,2016,39(1):170-173.
[12] 张立双,杨丰文,张俊华,等.桂枝茯苓胶囊/丸治疗慢性盆腔炎性疾病临床随机对照试验的系统评价[J].中国中药杂志,2017,42(8):1500-1509.
[13] 马 堃,罗颂平,李 敏,等.中医药防治盆腔炎性疾病优势与证据研究进展[J].中国中药杂志,2017,42(8):1449-1454.
[14] 李 红.腹腔镜手术联合红藤汤治疗盆腔脓肿58例临床观察[J].陕西医学杂志,2014,38(8):1095-1096.
[15] 龚 巍,万 莉,刘 娜.清热理血汤联合康妇消炎栓治疗老年急性盆腔炎的临床研究[J].中药药理与临床,2016,17(1):202-204.
[16] 李灵巧,沈 丹,钱 雁.益气温阳、活血化瘀法治疗湿热瘀结证盆腔炎性疾病后遗症疗效观察及对血液流变学、血清GM-CSF的影响[J].中华中医药学刊,2016,14(1):189-191.
[17] 吕品田,孙颖光,刘 斌.败酱草多糖的免疫调节作用及对S180荷瘤小鼠的影响研究[J].中药材,2017,5(1):11-12.

相似文献/References:

[1]赵小慧,王保莲,任国平,等.丹枝饮治疗盆腔炎后遗症寒凝血瘀疗效及对患者盆腔血流动力学影响*[J].陕西中医,2019,(9):1212.
 ZHAO Xiaohui,WANG Baolian,REN Guoping,et al.Effect of Danzhi decoction on pelvic hemodynamics in patients with pelvic inflammatory sequelae with Hanning Xueyu syndrome[J].,2019,(6):1212.

备注/Memo

备注/Memo:
*河南省医学科技攻关计划项目(201819134)
更新日期/Last Update: 2019-06-20