[1]冯惠娟.买氏理血祛风膏对维持性血液透析皮肤瘙痒患者疗效及安全性研究*[J].陕西中医,2019,(6):753-756.
 FENG Huijuan..Study on efficacy and safety of Mai’s Lixue Qufeng Gao for skin itching in maintenance hemodialysis patients[J].,2019,(6):753-756.
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买氏理血祛风膏对维持性血液透析皮肤瘙痒患者疗效及安全性研究*
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2019年6期
页码:
753-756
栏目:
临床研究
出版日期:
2019-06-05

文章信息/Info

Title:
Study on efficacy and safety of Mai’s Lixue Qufeng Gao for skin itching in maintenance hemodialysis patients
文章编号:
DOI:10.3969/j.issn.1000-7369.2019.06.020
作者:
冯惠娟
河南省中医药研究院附属医院(郑州 450004)
Author(s):
FENG Huijuan.
Henan Provincial Academy of Traditional Chinese Medicine Affiliated Hospital(Zhengzhou 450004)
关键词:
买氏理血祛风膏血液透析皮肤瘙痒肾功能临床疗效安全性
Keywords:
Key words Mai’s Lixue Qufeng GaoHemodialysisItchy skinRenal functionClinical efficacySecurity
分类号:
R758.3
文献标志码:
A
摘要:
摘 要 目的:探讨买氏理血祛风膏对维持性血液透析患者皮肤瘙痒的疗效及安全性。方法:选择80例行维持性血液透析皮肤瘙痒患者,按照随机数字表法分为两组,对照组予氯雷他定联合丁酸氢化可的松乳膏对症治疗,观察组在常规治疗上,加用自拟买氏理血祛风膏治疗,对比两组疗效及安全性情况。结果:观察组疾病疗效总有效率92.5%显著高于对照组总有效率75%( P <0.05)。观察组症候疗效总有效率90%显著高于对照组总有效率72.5%( P <0.05)。两组治疗前后血WBC及肝功能与本组自身比较无统计学差异( P >0.05),两组比较,治疗后也无统计学差异 ( P >0.05)。治疗后两组BUN、Scr均低于治疗前( P <0.05),Ccr高于治疗前( P <0.05)。两组比较,观察组肾功能各指标均优于对照组( P <0.05)。经治疗观察组患者血甲状旁腺素、血钙、血磷、Scr、BUN 水平则显著低于对照组 ( P <0.05)。结论:买氏理血祛风膏对改善维持性血液透析患者皮肤瘙痒症状疗效显著,安全性较好。
Abstract:
Abstract Objective:To explore the efficacy and safety of Mai’s Lixue Qufeng Gao for skin pruritus in maintenance hemodialysis patients.Methods:According to the random number table method,80 patients were divided into two groups.The control group was treated with conventional symptomatic treatment,and the observation group was treated with Mai’s Lixue Qufeng Gao on conventional treatment,and the efficacy and safety of the two groups were compared.Results:Total effective rate of diseases in the observation group was 92.5% significantly higher than 75% in the control group ( P <0.05).The total effective rate of symptomatic effect in the observation group was 90% higher than that of the control group 72.5% ( P <0.05).There was no significant difference in blood WBC and liver function between the two groups before and after treatment ( P >0.05).After treatment,both BUN,Scr and 24 hUP were significantly lower than before treatment ( P <0.05),and Ccr was significantly higher than before treatment ( P <0.05).Comparison between the two groups showed that all indicators of renal function in the observation group were significantly better than those in the control group ( P <0.05).After treatment,the levels of blood parathyroid hormone,blood calcium and blood phosphorus in the observation group were significantly lower than those in the control group ( P <0.05).Conclusion:It is effective to improve the skin pruritus symptoms of maintenance hemodialysis patients,safe and reliable,with few adverse reactions,and worthy of promotion.

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备注/Memo

备注/Memo:
*河南省中医药管理局科研项目(201816288D) 河南省中医药研究院科研项目(1804690)
更新日期/Last Update: 2019-06-20