[1]贺建涛,胡宇才,刘 磊.活血通络散治疗冠心病PCI术后心绞痛疗效研究*[J].陕西中医,2019,(7):854-857.
　HE Jiantao,HU Yucai,LIU Lei..Efficacy observation of Huoxue Tongluo powder in the treatment of angina pectoris after coronary heart disease PCI[J].,2019,(7):854-857.
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活血通络散治疗冠心病PCI术后心绞痛疗效研究*
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2019年7期
页码:
854-857
栏目:
临床研究
出版日期:
2019-07-05

文章信息/Info

Title:
Efficacy observation of Huoxue Tongluo powder in the treatment of angina pectoris after coronary heart disease PCI
文章编号:
DOI:10.3969/j.issn.1000-7369.2019.07.011
作者:
贺建涛1; 胡宇才2; 刘 磊
1.河南省巩义市中医院心病肺病科(巩义451200)；2.河南中医药大学第一附属医院心内科(郑州 450000)；3.河南中医药大学第三附属医院心内科(郑州 450008)
Author(s):
HE Jiantao; HU Yucai; LIU Lei.
Department of Heart Disease and Lung Disease,Gongyi Traditional Chinese Medicine Hospital in Henan Province(Gongyi 451200 )
关键词:
冠心病; 经皮冠状动脉介入治疗; 心绞痛; 心功能; 中西医联合治疗; 活血通络散
Keywords:
Key words Coronary heart disease; Percutaneous coronary intervention; Angina pectoris; Cardiac function; Chinese and western medicine combined treatment; Huoxue Tongluo powder
分类号:
R541.4
文献标志码:
A
摘要:
摘 要 目的：观察活血通络散应用于冠心病经皮冠状动脉介入（PCI）术后心绞痛治疗中的疗效。方法：选取PCI治疗后发生心绞痛的96例冠心病患者纳入研究，分为两组，其中对照组予以单纯常规西药治疗，观察组在此基础上应用活血通络散进行治疗；治疗1个疗程后，对比两组患者心绞痛与心电图临床疗效，统计两组心绞痛发生时间、每次持续时间，同时观察两组患者治疗前后心功能、血清标志物表达水平、心肌肌钙蛋白I（cTnI）水平的变化情况。结果：观察组心绞痛与心电图的临床总有效率依次为91.67%、87.50%，对照组依次为60.42%、56.25%，两组对比，观察组效果更好（P＜0.05）；治疗后，两组患者心绞痛发作情况、心功能指标、各项血清标志物水平与本组治疗前对比可见统计学意义（P＜0.05），且两组对比观察组效果更好（P＜0.05）。结论：活血通络散应用于冠心病PCI术后心绞痛治疗中，能够有效提高患者心绞痛与心电图临床疗效，降低心绞痛发作频率与时间，改善患者心功能并降低血清标志物与心肌酶学指标的表达水平。
Abstract:
Abstract Objective:To observe the efficacy of Huoxue Tongluo powder in the treatment of angina pectoris after percutaneous coronary intervention(PCI).Methods:96 patients with coronary heart disease who developed angina pectoris after receiving PCI treatment were selected as the observation data.All the selected patients were randomly divided into control group and observation group,the control group was given conventional treatment,and the observation group was treated with Huoxue Tongluo powder designed on the basis of the treatment of the control group;after one course of treatment,the clinical effects of angina pectoris and electrocardiogram in the two groups were compared,and the time and duration of angina pectoris in the two groups were counted,and the changes of cardiac function,serum marker expression level,and myocardial troponin I(cTnI) level in the two groups before and after treatment were observed.Results:The total clinical effective rate of angina pectoris in the observation group was 91.67%,and the total clinical effective rate of electrocardiogram was 87.50%,and that in the control group was 60.42%and 56.25%,respectively;after treatment,angina attack,cardiac function indexes and expression levels of various serum markers in the two groups were improved compared with those before treatment(P＜0.05),and the observation group was superior to the control group(P＜0.05).Conclusion:The application of Huoxue Tongluo powder in the treatment of angina after PCI of coronary heart disease can effectively improve the clinical efficacy of angina and electrocardiogram,reduce the frequency and time of angina attack,improve the cardiac function of patients and reduce the expression level of serum markers and myocardial enzymes.

参考文献/References:

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备注/Memo

备注/Memo:
*河南省科技攻关计划项目(201304062)
更新日期/Last Update: 2019-07-12