[1]赵小慧,王保莲,任国平,等.丹枝饮治疗盆腔炎后遗症寒凝血瘀疗效及对患者盆腔血流动力学影响*[J].陕西中医,2019,(9):1212-1215.
　ZHAO Xiaohui,WANG Baolian,REN Guoping,et al.Effect of Danzhi decoction on pelvic hemodynamics in patients with pelvic inflammatory sequelae with Hanning Xueyu syndrome[J].,2019,(9):1212-1215.
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丹枝饮治疗盆腔炎后遗症寒凝血瘀疗效及对患者盆腔血流动力学影响*
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2019年9期
页码:
1212-1215
栏目:
临床研究
出版日期:
2019-09-05

文章信息/Info

Title:
Effect of Danzhi decoction on pelvic hemodynamics in patients with pelvic inflammatory sequelae with Hanning Xueyu syndrome
文章编号:
DOI:10.3969/j.issn.10007369.2019.09.017
作者:
赵小慧1; 王保莲1; 任国平1; 申文彬2△; 殷 燕1
1.河南省新乡市中心医院产科三（新乡 453000）；2.陆军第83集团军医院心内科（新乡 453000）
Author(s):
ZHAO Xiaohui; WANG Baolian; REN Guoping; et al.
Department of Obstetrics,Xinxiang Central Hospital in Henan Province (Xinxiang 453000)
关键词:
丹枝饮; 盆腔炎后遗症; 寒凝血瘀证; 盆腔血流动力学; 临床疗效; 辨证论治
Keywords:
Key words Danzhi decoction; Pelvic inflammatory sequelae; Hanning Xueyu syndrome; Pelvic hemodynamics; Clinical efficacy; Bianzheng Lunzhi
分类号:
R711.33
文献标志码:
A
摘要:
摘 要 目的：探讨丹枝饮对盆腔炎后遗症寒凝血瘀证患者盆腔血流动力学影响及其临床疗效。方法：选择盆腔炎后遗症寒凝血瘀证患者153例，有77例纳入对照组，另76例纳入观察组。比较两组患者的血流动力学、临床疗效、炎性因子水平、气血指标，统计不良反应。结果：治疗后两组患者HR、MAP、CVP较治疗前升高，观察组患者HR、MAP、CVP高于对照组（P＜0.05）。治疗后两组患者中医症候积分较治疗前降低，观察组患者下腹冷痛、腰骶冷痛、带下量多、月经暗红、舌质暗淡、脉沉等的积分显著低于对照组（P＜0.05）。观察组患者临床总有效率显著高于对照组（P＜0.05)。治疗后两组患者的TNFα、IL6 水平低于治疗前（P＜0.05），观察组患者TNFα、IL6 水平显著低于对照组（P＜0.05）。观察组患者不良反应发生率低于对照组（P＞0.05）。治疗前两组患者血气指标差异比较无统计学意义（P＞0.05），治疗后两组患者的pH、PaO2水平高于治疗前（P＜0.05），观察组患者pH、PaO2水平高于对照组（P＜0.05）。结论：丹枝饮是改善盆腔炎后遗症寒凝血瘀证患者盆腔血流动力学、气血指标，提高临床疗效的有效方法。
Abstract:
Abstract Objective:To investigate the effect of Danzhi decoction on pelvic hemodynamics in patients with pelvic inflammatory sequelae with Hanning Xueyu syndrome.Methods:153 cases of pelvic inflammatory sequelae with cold blood stasis syndrome treated were selected and divided into two groups.77 patients in the control group 76 patients in the observation group,then the Hemodynamics,clinical efficacy,inflammatory factor levels,Qixue blood indicators,and adverse reactions were compared between groups.Results:The HR,MAP and CVP were increased after treatment,and were higher in the observation group than in the control group (P＜0.05).The TCM symptom scores had no difference between groups before treatment,which were decreased after treatment,and were lower in the observation group than in the control group (P＜0.05).The total efficacy rate was higher in the observation group than in the control group (P＜0.05).The levels of TNFα and IL6 were decreased after treatment,and were lower in the observation group than in the control group (P＜0.05).pH and PaO2 levels had no difference between groups before treatment,which were increased after treatment,and were higher in the observation group than in the control group (P＜0.05).Conclusion：The application of Danzhi decoction can effectively ameliorate the pelvic hemodynamics and Qi and blood indicators for pelvic inflammatory sequelae patients with Hanning Xueyu syndrome,which is recommended.

参考文献/References:

[1] 梁 照,许 琳,金 哲.丹枝饮对气滞血瘀型盆腔炎性疾病后遗症慢性盆腔痛的临床疗效观察[J] .中国中医基础医学杂志,2017，33(4):518520.
[2] 卜晓玲，黄文玲，徐 翠，等.丹枝饮对小鼠盆腔炎性疾病后遗症盆腔血运的影响[J] .吉林中医药,2016,18(6):189193.
[3] 梁 照,鲁秋丹,金 哲.丹枝饮对盆腔炎性疾病后遗症小鼠体内炎性因子的影响[J] .天津中医药大学学报,2017,36(1):3337.
[4] Zhou Z ,Zeng F ,Yuan J,et al.Pelvic inflammatory disease and the risk of ovarian cancer:a metaanalysis[J] .Cancer Causes & Control,2017,28(3):114.
[5] 许 琳,庄雨龙,金 哲.丹枝饮对盆腔炎性疾病后遗症小鼠JNK信号传导通路及相关炎性因子的影响[J] .北京中医药大学学报,2017,29(10):839844.
[6] 庄雨龙,许 琳,金 哲.基于P38信号传导通路探讨丹枝饮治疗盆腔炎性疾病后遗症机制的实验研究[J] .世界中西医结合杂志,2018,18(6):357364.
[7] 李灵巧,沈 丹,钱 雁.益气温阳、活血化瘀法治疗湿热瘀结证盆腔炎性疾病后遗症疗效观察及对血液流变学、血清GMCSF的影响[J] .中华中医药学刊,2016,18(1):189191.
[8] 宋 丹,刘金星,师 伟,等.盆腔炎性疾病后遗症动物模型不同病原体感染的对比分析[J] .成都中医药大学学报,2016,39(2):1518.
[9] 唐敏洁,张勤华.丹芍消炎合剂联合静脉抗生素预防盆腔炎性疾病后遗症[J] .辽宁中医杂志,2016,10(3):557559.
[10] Cheng Y ,Yuan Y ,Jin Y,et al.Acupuncture for chronic pelvic inflammatory disease[J] .Medicine,2018,97(13):e0225.
[11] Wolff M,Balamuth F,Sampayo E,et al.Improving adolescent pelvic inflammatory disease followup from the emergency department:randomized controlled trial with text messages[J] .Annals of Emergency Medicine,2016,67(5):602609.e3.
[12] Jone AD.Antiinflammatory effect of manpenfang,Chinese herbal compound,on chronic pelvic inflammation in rats[J] .Journal of ethnopharmacology,2017,208:5765.
[13] 郝美峰,靳晓乐,王玉兰,等.丹鳖胶囊治疗盆腔炎性疾病气滞血瘀证的临床观察[J] .中国药物与临床,2017,17(4):578579.
[14] 韩 云,王兆霞.逍遥逐瘀汤辅助治疗气滞血瘀型盆腔炎性疾病后遗症临床疗效及对患者盆腔积液及包块情况的影响[J] .四川中医,2018,17(1):146148.
[15] 李 捷,高月平.高月平教授治疗肾虚血瘀型盆腔炎性疾病后遗症的经验[J] .浙江中医药大学学报,2017,85(12):975977.
[16] 吕姝菡,刘金星,师 伟,等.老年盆腔炎性疾病后遗症反复发作的中医证候分布规律探析[J] .辽宁中医杂志,2017,17(6):11441146.
[17] 刘伟婷,刘金星,师 伟,等.盆腔炎性疾病后遗症证候动物模型研究概述[J] .山东中医药大学学报,2016,21(6):576578.
[18] Long B ,April MD.What antibiotic regimen is most efficacious in treating pelvic inflammatory disease[J] .Annals of Emergency Medicine,2017,70(6):840.
[19] 吕姝菡,刘金星,师 伟,等.逍遥舒坤汤口服联合灌肠对盆腔炎性疾病后遗症的治疗效果及免疫学影响[J] .辽宁中医杂志,2018,24(6):564569.
[20] 陶 莎,宋长红,王继坤,等.温和灸联合微波理疗对慢性盆腔炎气滞血瘀证型护理效果观察[J] .护理学杂志,2016,31(12):4749.

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备注/Memo

备注/Memo:
*河南省医学科技攻关计划项目(201602501)
更新日期/Last Update: 2019-09-24