[1]周智恩,卢 萍,徐向文,等.安神解郁汤联合针刺百会穴治疗脑卒中后抑郁多中心随机平行对照研究[J].陕西中医,2020,(3):390-393.
 ZHOU Zhien,LU Ping,XU Xiangwen,et al.Multi-center randomized parallel-controlled clinical study on efficiency of Anshen Jieyu decoction combined with acupuncture at Baihui point in treating post-stroke depression[J].,2020,(3):390-393.
点击复制

安神解郁汤联合针刺百会穴治疗脑卒中后抑郁多中心随机平行对照研究
分享到:

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2020年3期
页码:
390-393
栏目:
针灸经络
出版日期:
2020-03-05

文章信息/Info

Title:
Multi-center randomized parallel-controlled clinical study on efficiency of Anshen Jieyu decoction combined with acupuncture at Baihui point in treating post-stroke depression
文章编号:
DOI:10.3969/j.issn.10007369.2020.03.034
作者:
周智恩1卢 萍1徐向文2杜卫甫4
1.成都市第一人民医院重症医学科(成都 610017); 2.山东省临沂市第一人民医院神经内科(临沂 276003); 3.安徽中医药大学附属医院神经内科(合肥 230061)
Author(s):
ZHOU ZhienLU PingXU Xiangwenet al.
Department of Critical Care Medicine,Chengdu First People's Hospital(Chengdu 610017)
关键词:
脑卒中后抑郁 针刺疗法 针药结合 多中心随机平行对照研究
Keywords:
Post-stroke depression Acupuncture Combination of acupuncture and medicine Multi-center randomized parallel-controlled clinical study
分类号:
R255.2
文献标志码:
A
摘要:
目的:观察安神解郁汤联合针刺百会穴治疗脑卒中后抑郁的疗效。方法:使用随机平行对照方法,将225例住院患者按抽签方法随机分为两组,对照组85例,给予西医综合治疗。治疗组140例,加用安神解郁汤联合针刺百会穴,西药治疗同对照组。两组患者于治疗前后分别进行汉密尔顿抑郁量表(HAMD)评分、日常生活活动能力(ADL)和神经功能缺损程度(NIHSS)评分评定。结果:治疗组和对照组抗抑郁疗效总有效率分别为92.14%、80.00%; 神经功能疗效总有效率分别为93.57%、49.41%,差异均有统计学意义(P<0.05)。HAMD、ADL、NIHSS评分均有显著改善(P<0.01),治疗组改善优于对照组(P<0.05)。均无明显不良反应。结论:安神解郁汤联合针刺百会穴治疗脑卒中后抑郁的疗效显著。
Abstract:
Objective:To observe the clinical effect of treating post-stroke depression(PSD)with self-made Anshen Jieyu decoction combined with acupuncture at Baihui point.Methods:225 patients according to the draw method were randomly divided into two groups.The control group of 85 cases were treated with conventional routine.The treatment group of 140 cases plused self-made Anshen Jieyu decoction and acupuncture at Baihui point.The therapeatic effects were evaluated by the Hamiltom depression scale(HAMD),Activites of daily living(ADL)and National institute of health stroke scale(NIHSS).Results:The total effective rate of anti-depression was respepectively 92.12% in the treatment group and 80.00% in the control group.The total effective rate of neurological function was respepectively 93.55% and 49.41%.The efficancy of anti-depression and neurological function between before and after treatment contrast were significance difference(P<0.05).Degress of HAMD,ADL and NIHSS were improved in the two groups after treatment and the differences were statistically significant(P<0.01).The therapeutic efficacy of the treatment group was markely superior to that of the control group(P<0.05).No obvious adverse events was seen in the treatment period.Conclusion:Self-made Anshen Jieyu decoction combined with acupuncture at Baihui point in treating PSD is a significent effective treatment,so it is worth popularizing.

参考文献/References:

[1] 侯吉星,权乾坤.舒肝解郁胶囊对轻中度脑卒中后抑郁患者神经认知功能的疗效分析[J].陕西中医,2016,37(7):817-818.
[2] Yuan HW,Wang CX,Zhang N,et al.Poststroke depression and risk of recurrent stroke at 1 year in a Chinese cohort study[J].PLoS One,2012,7(10):E46906.
[3] 王雪茵,胡永华.脑卒中流行病学的家系研究[J].中华流行病学杂志,2013,34(6):647-649.
[4] 中华神经科学会.各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380.
[5] 张明圆.精神科评定量表手册-新精神医学丛书[M].北京:科学技术出版社,2003:2-4.
[6] 马聪吉,杜晓华,杨为民.缺血性脑卒中的病理机制及药物研究进展[J].医学信息,2014,27(11):538-539.
[7] 刘金榜.柴胡龙骨牡蛎汤联合抗抑郁药物治疗脑卒中后抑郁的肝肾阴虚证的临床研究[J].陕西中医,2016,37(2):155-157.
[8] Berg A,Psych L,Palomaki H,et al.Poststroke depression-an 18-month follow-up[J].Stroke,2003,34(1):138-143.
[9] 陈青萍.现代临床心理学[M].北京:中国社会科学出版社,2004:199-200.
[10] 冯建伟,张海生,边双义.茯苓竹茹汤联合盐酸舍曲林治疗脑卒中后抑郁状态临床观察[J].陕西中医,2017,38(8):987-988.
[11] Eriksson TM,Delagrange P,Spedding M,et al.Emotional memory im-pairments in a genetic rat model of depression:involvement of 5 -HT/ MEK/ Arc signaling in restoration[J].Mol Psychiatry,2012,17(2):173-184.
[12] 许文杰,蒋瑞冲,周一心,等.王翘楚教授经验方治疗肝郁瘀阻型脑卒中后失眠临床研究[J].陕西中医,2019,40(7):867- 870.
[13] 常 诚.脑卒中后抑郁与抑郁症中医辨治异同的探讨[J].陕西中医,2009,30(2):184-185.
[14] 许文杰,蒋瑞冲,周一心,等.活血疏肝法治疗脑卒中后抑郁临床观察[J].陕西中医,2019,40(10):1354- 1356.
[15] 李岩琪,白 杨,陈静子,等.腧穴配伍研究现状若干问题的思考[J].北京中医药大学学报,2014,37(8):523-525.
[16] 蒋 岚,田慧军,黄 伟.针灸联合黛力新治疗脑卒中后抑郁疗效及对患者血清神经递质水平的影响[J].陕西中医,2019,40( 8 ):1134- 1137.

相似文献/References:

[1]许文杰,蒋瑞冲,周一心,等.活血疏肝法治疗脑卒中后抑郁临床观察*[J].陕西中医,2019,(10):1354.
 XU Wenjie,JIANG Ruichong,ZHOU Yixin,et al.Therapeutic observation of activating blood circulation and soothing the liver for poststroke depression[J].,2019,(3):1354.
[2]余华,常江,党玉琳,等.化痰活络饮联合低频重复经颅磁刺激治疗脑卒中后抑郁疗效分析*[J].陕西中医,2019,(11):1528.
[3]王远庆,吴耀持.超微针刀网点状松解法对腰椎间盘突出症患者VAS评分和JOA腰椎疾患评分的影响[J].陕西中医,2020,(4):541.
 WANG Yuanqing,WU Yaochi..The effect of ultra fine needle knife on VAS score and JOA lumbar disease score in patients with lumbar disc herniation[J].,2020,(3):541.
[4]姚苗苗,李永峰,金如玉,等.针刺论治原发性高血压病临床研究进展*[J].陕西中医,2020,(5):693.[doi:DOI:10.3969/j.issn.10007369.2020.05.039]
[5]李大雷,赵灿伟.针刺治疗脑卒中后抑郁疗效研究[J].陕西中医,2020,(10):1489.[doi:DOI:10.3969/j.issn.1000-7369.2020.10.042]
[6]高 婷,潘 婕,刘婧斐,等.针刺治疗脑卒中后平衡功能障碍研究进展[J].陕西中医,2021,(5):677.[doi:DOI:10.3969/j.issn.1000-7369.2020.05.033]
 GAO Ting,PAN Jie,LIU Jingfei,et al.Research Progress of Acupuncture on Balance Dysfunction after Stroke[J].,2021,(3):677.[doi:DOI:10.3969/j.issn.1000-7369.2020.05.033]
[7]姜 锐,彭福梅,徐珊珊,等.养阴利咽汤联合针刺治疗慢性咽炎及对患者临床症状、炎性因子和免疫功能的影响[J].陕西中医,2022,(2):257.[doi:DOI:10.3969/j.issn.1000-7369.2022.02.028]
 JIANG Rui,PENG Fumei,XU Shanshan,et al.Effect of Yangyin Liyan decoction combined with acupuncture on clinical symptoms,inflammatory factors and immune function of patients with chronic pharyngitis[J].,2022,(3):257.[doi:DOI:10.3969/j.issn.1000-7369.2022.02.028]
[8]冷 凤,史 玲,刘丽莉.针刺调控p38MAPK/NF-κB信号通路对脑卒中后抑郁症大鼠干预机制[J].陕西中医,2022,(3):292.[doi:DOI:10.3969/j.issn.1000-7369.2022.03.005]
[9]谢灿明,王 瑶,向 静,等.“或针结,针着大肠泄水穴”理论探析[J].陕西中医,2023,(10):1424.[doi:DOI:10.3969/j.issn.1000-7369.2023.10.020]
[10]王鲁扬,刘源香.中医外治法治疗偏头痛疗效Meta分析[J].陕西中医,2023,(11):1640.[doi:DOI:10.3969/j.issn.1000-7369.2023.11.036]
 WANG Luyang,LIU Yuanxiang.Meta analysis of the curative effect of TCM external treatment on migraine[J].,2023,(3):1640.[doi:DOI:10.3969/j.issn.1000-7369.2023.11.036]

更新日期/Last Update: 2020-04-07