[1]许春梅,吴雪茹,周敏婷,等.温通膏外敷联合红外线照射治疗肌注黄体酮所致局部反应疗效及对患者免疫功能的影响*[J].陕西中医,2020,(8):1121.[doi:DOI:10.3969/j.issn.1000-7369.2020.08.029]
 XU Chunmei,WU Xueru,ZHOU Minting,et al.Clinical effect of external application of Wentong paste combined with infrared ray irradiation on local response of progesterone and immune function of patients[J].,2020,(8):1121.[doi:DOI:10.3969/j.issn.1000-7369.2020.08.029]
点击复制

温通膏外敷联合红外线照射治疗肌注黄体酮所致局部反应疗效及对患者免疫功能的影响*
分享到:

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2020年8期
页码:
1121
栏目:
临床研究
出版日期:
2020-08-05

文章信息/Info

Title:
Clinical effect of external application of Wentong paste combined with infrared ray irradiation on local response of progesterone and immune function of patients
作者:
许春梅1吴雪茹2周敏婷1肖 珊1
1.广州中医药大学第三附属医院妇二科(广州 510378); 2.广州中医药大学药学部(广州 510378)
Author(s):
XU ChunmeiWU XueruZHOU Mintinget al.
Department II of Gynecology,Affiliated Hospital of Guangzhou University of Chinese Medicine(Guangzhou 510378)
关键词:
温通膏 红外线照射 黄体酮 局部反应 免疫功能水平 β-人绒毛膜促性腺激素
Keywords:
Wentong plaster Infrared radiation Progesterone Local reaction Immune function β-HCG
分类号:
R714.21
DOI:
DOI:10.3969/j.issn.1000-7369.2020.08.029
文献标志码:
A
摘要:
目的:探讨温通膏外敷联合红外线照射对黄体酮所致局部反应临床疗效及对患者免疫功能的影响。方法:选择先兆流产并肌注黄体酮病例共280例,其中出现局部反应体征病例100例,根据随机数字表法分为联合组和对照组各50例,对照组给予红外线照射治疗,联合组患者在此基础上联合温通膏外敷治疗,两组均为2周1个疗程。观察两组临床疗效,并对两组患者免疫功能水平、孕酮和β-HCG水平、症状积分变化情况进行比较。结果:联合组治疗有效率高于对照组(χ2=8.491,P=0.014)。治疗前,两组患者免疫功能水平比较,差异无统计学意义(P>0.05),治疗后两组指标均明显上升,联合组患者CD4+、CD8+和CD4+/ CD8+水平等指标上升/降低幅度更明显,差异有统计学意义(P<0.05)。治疗前,两组患者孕酮和β-HCG水平比较,差异无统计学意义(P>0.05),治疗后联合组患者孕酮和β-HCG水平等指标上升幅度更明显,差异有统计学意义(P<0.05)。治疗前,两组患者症状积分比较,差异无统计学意义(P>0.05),治疗后联合组患者小腹疼痛、阴道流血、腰酸胀痛和两膝酸软降低程度更加明显,差异有统计学意义(P<0.05)。结论:温通膏外敷联合红外线照射对黄体酮所致局部反应治疗疗效显著,可明显改善患者局部反应症状和免疫功能水平。
Abstract:
Objective:To explore the effect of Wentong plaster combined with infrared radiation on progesterone and the immune function of patients.Methods:A total of 280 cases of threatened abortion with progesterone injection in our hospital were selected,among which 100 cases developed local reaction symptoms.According to the random number table method,the 100 patients were divided into the combined group and the control group,with 50 cases in each group.The control group was given infrared radiation treatment,and the combined group was given Wentong plaster external application for combined treatment on the basis of treatment in the control group.Both groups were treated with one cycle of two weeks.Results:The effective rate of the combined group was higher than that of the control group(χ2=8.491,P=0.014).Before treatment,there was no significant difference in the level of immune function between the two groups(P>0.05), which,however,increased significantly in the two groups after treatment,and there was more significant increase/decrease in the level of CD4+,CD8+ and CD4+/CD8+ in the combined group(P<0.05).Before treatment,there was no significant difference in progesterone and β-hCG levels between the two groups(P>0.05).After treatment,the levels of progesterone and β-HCG increased more significantly in the combined group,with statistical difference(P<0.05).Before treatment,there was no significant difference in symptom scores between the two groups(P>0.05).After treatment,patients in the combined group had more significant reduction in abdominal pain,vaginal bleeding,backache and tenderness of the knees(P<0.05).Conclusion:External application of wentong paste combined with infrared irradiation has a significant effect on the local response of progesterone,which can significantly improve the local response symptoms and immune function of patients.

参考文献/References:

[1] 李红霞,宋淑红,李姬梅.黄体酮治疗先兆流产患者的临床效果及对妊娠结局的影响[J].医疗装备,2018,31(22):87-88.
[2] 李丽萍,吴德容,冯丽萍.固肾安胎丸联合地屈孕酮治疗早期先兆流产的应用价值[J].海峡药学,2018,30(3):106-107.
[3] 李 波.黄体酮用于治疗黄体功能不全所致先兆流产的临床观察[J].中华护理杂志,2017,9(17):224.
[4] 郑 新,秦小莲,王缉义,等.黄体酮在妇产科外领域的研究及临床应用进展[J].中国药房,2016,27(16):2292-2295.
[5] 周琴丽.黄体酮治疗黄体功能不全所致先兆流产的临床效果[J].现代医药卫生,2018,12(41):127.
[6] 张 华,张红英,袁宁霞.探讨黄体酮对孕妇黄体功能不全所致的先兆流产的治疗效果[J].陕西医学杂志,2016,45(4):425-426.
[7] 俞传江.固肾安胎丸联合黄体酮对早孕先兆流产的保胎效果观察[J].中国医药指南,2017,15(21):190-191.
[8] 王文萍,党 军.固肾安胎丸联合黄体酮软胶囊治疗早期先兆流产60例[J].陕西中医,2016,37(11):1451-1452.
[9] 周维侠.固肾安胎丸联合复方黄体酮注射液治疗先兆流产的疗效分析[J].临床合理用药杂志,2016,9(15):96-97.
[10] 苏亚璞.分析安宫黄体酮辅助刮宫术治疗围绝经期功能失调性子宫出血的临床效果[J].海峡药学,2019,31(6):229-230.
[11] 何晓庆.黄体酮对孕妇黄体功能不全所致的先兆流产的治疗效果[J].中国实用护理杂志,2019,1(32):205.
[12] 张淑爱,孙金凤.红外线照射应用在人工流产术后的临床价值[J].中国医药指南,2013,11(9):213.
[13] 孟 柳.红外线理疗促进会阴切口愈合的临床观察和体会[J].医学信息,2013,34(16):631.
[14] 张淑爱,孙金凤.红外线照射改善人工流产患者局部微循环的效果研究[J].海南医学,2014,25(11):1608-1610.
[15] 梁启军,曾 茹,周 琳.妊娠禁忌与安胎中药[J].中医杂志,2018,59(23):2068-2070.
[16] 张慧雯,乔成平.胎元饮改善气血虚弱型先兆流产患者免疫机制探讨[J].临床与病理杂志,2018,38(8):1725-1729.
[17] 国家中医药管理局.中医病证诊断疗效标准[M].南京:南京大学出版社,1994: 201-202.
[18] 徐必达,吴 宾,黄艳环,等.温通膏的研制与质量考察[J].广东药学,2004,14(2):31-34.
[19] 郭雪霞,吴雪茹,黄晓冰,等.温通膏治疗风寒湿证膝关节骨性关节炎的临床观察[J].中药材,2017,40(10):2466-2468.

备注/Memo

备注/Memo:
*广东省中医药局科研项目(20183007)
更新日期/Last Update: 2020-08-10