[1]杨玉华,杨 阳,曾成惠,等.中医适宜技术治疗经尿道前列腺切除术后下尿路症候群疗效及对患者排尿功能的影响[J].陕西中医,2021,(4):489-492.[doi:DOI:10.3969/j.issn.1000-7369.2020.04.022]
　YANG Yuhua,YANG Yang,ZENG Chenghui,et al.Curative effect of appropriate TCM technology on lower urinary tract symptoms after transurethral resection of the prostate and its influences on urination function[J].,2021,(4):489-492.[doi:DOI:10.3969/j.issn.1000-7369.2020.04.022]
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中医适宜技术治疗经尿道前列腺切除术后下尿路症候群疗效及对患者排尿功能的影响

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2021年4期
页码:
489-492
栏目:
临床研究
出版日期:
2021-04-05

文章信息/Info

Title:
Curative effect of appropriate TCM technology on lower urinary tract symptoms after transurethral resection of the prostate and its influences on urination function
作者:
杨玉华; 杨 阳; 曾成惠; 姜 岚; 胡静杰
(四川省第二中医医院,四川 成都 610000)
Author(s):
YANG Yuhua; YANG Yang; ZENG Chenghui; JIANG Lan; HU Jingjie
(Sichuan No.2 Hospital of Traditional Chinese Medicine,Chengdu 610000,China)
关键词:
中医适宜技术;  经尿道前列腺切除;  下尿路症候群;  β-内啡肽;  排尿功能;  前列腺评分
Keywords:
Appropriate TCM technology;  Transurethral resection of the prostate;  Lower urinary tract syndrome;  β-endorphin;  Urination function;  Prostate score
分类号:
R 697.3
DOI:
DOI:10.3969/j.issn.1000-7369.2020.04.022
文献标志码:
A
摘要:
目的:探讨中医适宜技术治疗经尿道前列腺切除术(TURP)后下尿路症候群的疗效及对患者排尿功能的影响。方法:采用信封法将行TURP患者108例分为研究组(n=55)和对照组(n=53),对照组采用西医治疗,研究组在此基础上给予中医适宜技术治疗,比较两种治疗方式疗效,并分析对患者中医证候、排尿功能的影响。结果:两组疗效比较差异有统计学意义(94.55% 与78.18%,P<0.05); 治疗后研究组尿频、尿急、尿痛症状积分均显著低于对照组(P<0.05); 治疗后两组最大膀胱容量(MCC)、残余尿量(PRV)、最大尿流速(Qmax)、最大逼尿肌压(Pdet)均显著升高,且研究组以上指标均明显高于对照组(P<0.05); 治疗后两组前列腺素E2(PGE2)、β-内啡肽(β-EP)均显著升高,前列腺素F2α(PGF2α)降低,且研究组PGE2、β-EP高于对照组,PGF2α低于对照组(P<0.05); 治疗后两组前列腺症状评分(IPSS)及膀胱过度活动症状评分(OABSS)均显著降低,且研究组以上评分均明显低于对照组(P<0.05)。结论:中医适宜技术在经尿道前列腺切除患者中应用较佳,可显著改善患者术后下尿路症候群、前列腺增生及排尿功能,减轻膀胱过度活动。
Abstract:
Objective:To explore the curative effect of appropriate TCM technology on lower urinary tract symptoms(LUTS)after transurethral resection of the prostate(TURP)and its influences on urination function.Methods:A total of 108 patients who underwent TURP were divided into study group(n=55)and control group(n=53)by envelop method.The control group was treated with western medicine,while study group was given appropriate TCM technology on this basis.The curative effect of the two treatment methods was compared.And their influences on TCM symptoms and urination function were analyzed.Results:There was significant difference in curative effect between the two groups(94.55%vs78.18%,P<0.05).After treatment,scores of frequent urination,urgent urination and dysuria in study group were significantly lower than those in control group(P<0.05).After treatment,maximum cystometric capacity(MCC),postvoid residual volume(PRV),maximum flow rate(Qmax)maximum detrusor pressure(Pdet)in both groups were significantly increased,which were significantly higher in study group than control group(P<0.05).After treatment,prostaglandin E2(PGE2)and β-endorphin(β-EP)in both groups were significantly increased,while prostaglandin F2α(PGF2α)was decreased.PGE2 and β-EP in study group were higher than those in control group,while PGF2α was lower than that in control group(P<0.05).After treatment,international prostate symptom score(IPSS)and Overactive Bladder Symptom Score(OABSS)in both groups were significantly decreased,which were significantly lower in study group than control group(P<0.05).Conclusion:The application of appropriate TCM technology is good in TURP patients,which can significantly improve postoperative LUTS,prostatic hyperplasia and urination function,reduce overactive bladder.

参考文献/References:

[1] 邱 智,吴栗洋,周晓光,等.良性前列腺增生致膀胱出口梗阻合并逼尿肌功能减弱患者行经尿道前列腺电切术疗效的影响因素分析[J].中华泌尿外科杂志,2016,37(7):511-514.
[2] 陈 延,孙 超,甄福康,等.良性前列腺增生患者经尿道前列腺等离子双极电切术后夜尿改善情况研究[J].河北医药,2020,42(19):2931-2934.
[3] 黄达坤,林 峰,李海馨,等.电针联合热敏灸对良性前列腺增生患者血清PSA、TNF-α、IL-6、EGF的影响[J].中医学报,2019,34(8):1783-1787.
[4] 杨登科,杜 广,方 震,等.经尿道前列腺剜除术后患者的排尿症状改变分析[J].广东医学,2016,37(2):254-255.
[5] 朱文座,李 刚,李 奎,等.经尿道前列腺电切术中切除的组织大小对术后近期疗效的分析[J].中华男科学杂志,2016,22(9):813-816.
[6] 梁学清,于 兵,李丹丹,等.经尿道前列腺汽化电切术联合钬激光碎石术同期治疗良性前列腺增生症合并膀胱结石的临床疗效[J].中国老年学杂志,2016,35(1):146-148.
[7] 吴阶平.吴阶平泌尿外科学[M].济南:山东科学技术出版社,2004:1144.
[8] 国家中医药管理局.中医病症诊断疗效标准[M].南京:南京大学出版社,1994:186-189.
[9] 钟 萍,赵耀瑞,杨福江,等.逼尿肌活力低下对良性前列腺梗阻患者经尿道前列腺切除术疗效的影响[J].中华泌尿外科杂志,2017,38(11):815-819.
[10] 苏志勇,刘洪明,田 野,等.移行带指数对经尿道前列腺电切术疗效的影响分析[J].中华医学杂志,2020,100(6):452-455.
[11] 李伟光,臧运江,陈琳琳,等.经尿道等离子前列腺电切术联合睾丸切除术治疗中晚期前列腺癌的临床疗效及对前列腺特异抗原水平的影响[J].中国肿瘤临床与康复,2016,23(3):315-318.
[12] 唐荣志,赖海标,钟 亮,等.补中益气法对前列腺癌根治术后尿失禁患者控尿、排尿功能及生活质量的影响[J].辽宁中医杂志,2019,46(12):2599-2602.
[13] 曾 玉,朱智虎,王 伟,等.过渡期干预对前列腺切除术后患者排尿功能、生活质量和性生活的影响[J].中国性科学,2020,29(3):14-17.
[14] 刘东波,殷德科,古孝良,等.小蓟饮子加减方治疗良性前列腺增生症经尿道双极等离子汽化电切术后出血临床观察[J].陕西中医,2017,38(11):1540-1541.
[15] 饶建明,任毅馨,何 江,等.前列腺大小对经尿道等离子剜除治疗良性前列腺增生疗效和手术并发症的影响[J].中国医师杂志,2016,18(4):557-561.
[16] 雒向宁,杜宏宏,刘 凯,等.经尿道“分叶式”剜除联合电切治疗前列腺增生应用观察[J].陕西医学杂志,2018,47(6):742-744.
[17] 徐 磊,车宪平,古 军,等.经尿道前列腺汽化电切术联合钬激光碎石术治疗BPH合并膀胱结石的疗效[J].检验医学与临床,2018,15(6):778-781.
[18] 陈禹杰,何云锋,张 尧,等.经尿道柱状水囊前列腺扩开术治疗中年及高危患者良性前列腺增生[J].重庆医学,2017,46(32):4523-4525.
[19] 钱 余,周恩谱,黄进宝,等.经尿道前列腺汽化电切术后继发囊性膀胱炎(8例报告)[J].中国微创外科杂志,2018,18(5):473-475.
[20] 陈 岚,梅雪峰,赵 娟,等.通淋止血汤联合托特罗定治疗经尿道前列腺电切术后膀胱过度活动症临床疗效评价[J].四川中医,2019,37(11):132-135.

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备注/Memo

备注/Memo:
基金项目:四川省公益性科研院所基本科研项目(20-4-566)
更新日期/Last Update: 2021-04-09