[1]吴民民,刘小华,陈小雨,等.浮针配合再灌注治疗原发性三叉神经痛临床研究[J].陕西中医,2021,(5):646-649,653.[doi:DOI:10.3969/j.issn.1000-7369.2020.05.026]
　WU Minmin,LIU Xiaohua,CHEN Xiaoyu,et al.Floating acupuncture combined with reperfusion in the treatment of primary trigeminal neuralgia[J].,2021,(5):646-649,653.[doi:DOI:10.3969/j.issn.1000-7369.2020.05.026]
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浮针配合再灌注治疗原发性三叉神经痛临床研究
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2021年5期
页码:
646-649,653
栏目:
针灸经络
出版日期:
2021-05-05

文章信息/Info

Title:
Floating acupuncture combined with reperfusion in the treatment of primary trigeminal neuralgia
作者:
吴民民1; 刘小华1; 陈小雨1; 李崖雪2
(1.黑龙江中医药大学,黑龙江 哈尔滨150040; 2.黑龙江中医药大学附属第一医院,黑龙江 哈尔滨150040)
Author(s):
WU Minmin; LIU Xiaohua; CHEN Xiaoyu; LI Yaxue
(Heilongjiang University of Chinese Medicine,Harbin 150040,China)
关键词:
三叉神经痛;  浮针;  再灌注;  血清炎症因子;  卡马西平
Keywords:
Trigeminal neuralgia;  Floating needle;  Reperfusion;  Serum inflammatory factors;  Carbamazepine
分类号:
R 246.6
DOI:
DOI:10.3969/j.issn.1000-7369.2020.05.026
文献标志码:
A
摘要:
目的:探究浮针配合再灌注治疗原发性三叉神经痛的临床疗效。方法:将收治的60例患者纳入本次研究,以随机数字表法将其分为治疗组和对照组,各30例。治疗组接受浮针配合再灌注治疗,对照组接受西药常规治疗。治疗4周后,比较两组患者Mc-Gill疼痛量表评分、综合症状评分、生活满意度指数(LSI-B)、血清炎症因子指标变化以及氧化应激水平变化、临床治疗效果及不良事件的发生。结果:两组患者治疗后视觉模拟效果(VAS)、现有疼痛强度(PPI)、疼痛分级指数(PRI)评分均明显低于治疗前,且治疗组患者明显低于对照组,差异均有统计学意义(P<0.05); 两组患者治疗后LSI-B、综合症状评分均明显低于治疗前,且治疗组患者明显低于对照组,差异均有统计学意义(P<0.05); 两组患者治疗后血清炎症因子白细胞介素-1β(IL-1β)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)水平均明显低于治疗前,且治疗组患者明显低于对照组,差异具有统计学意义(P<0.05); 两组患者治疗后氧化应激SOD、GSH-Px浓度水平均明显高于治疗前,且治疗组患者明显高于对照组,差异具有统计学意义(P<0.05); 治疗组患者临床疗效总有效率90.00%,明显高于对照组83.33%,差异具有统计学意义(Z=-2.32,P=0.02); 两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论:浮针配合再灌注治疗三叉神经痛患者临床症状显著改善,有效缓解患者疼痛,炎症反应及氧化应激反应水平降低。
Abstract:
Objective:To explore the clinical efficacy of floating acupuncture combined with reperfusion in the treatment of primary trigeminal neuralgia.Methods:Sixty patients with trigeminal neuralgia were included in this study.They were divided into treatment group and control group by random number method,with 30 cases each.The treatment group received floating needle combined with reperfusion treatment,and the control group received routine western medicine treatment.After 4 weeks of treatment,the Mc-Gill pain scale score,comprehensive symptom score,life satisfaction index(LSI-B),serum inflammatory factors,oxidative stress level,clinical treatment effect and adverse events were compared between the two groups.Results:After treatment,the scores of VAS,PPI and PRI in the two groups were significantly lower than those in the control group(P<0.05),and the scores of LSI-B and comprehensive symptoms in the treatment group were significantly lower than those in the control group(P<0.05).The levels of serum inflammatory factors IL-β,IL-6 and TNF-α in the two groups after treatment were significantly lower than those before treatment,and those in the treatment group were significantly lower than those in the control group(P<0.05),and the levels of oxidative stress SOD and GSH-Px in the two groups were significantly higher than those before treatment,and the levels of oxidative stress in the treatment group were significantly higher than those in the control group(P<0.05).The total clinical effective rate of patients in the treatment group was 90.00%,which was significantly higher than that in the control group 83.33%,and the difference was statistically significant(Z=-2.32,P=0.02).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Floating acupuncture combined with reperfusion is effective in the treatment of trigeminal neuralgia,the clinical symptoms of the patients are significantly improved,the pain is effectively relieved,and the levels of inflammatory reaction and oxidative stress are reduced.

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备注/Memo

备注/Memo:
基金项目:黑龙江省自然科学基金资助面上项目(H2015033); 黑龙江省中医药科研项目(ZHY2020-106)
更新日期/Last Update: 2021-05-10