[1]黄祖鸿,石清兰,柏文婕,等.毛德文教授运用“调肝理脾”法治疗慢性肝病经验总结[J].陕西中医,2021,(8):1112-1114,1119.[doi:DOI:10.3969/j.issn.1000-7369.2020.08.031]
　HUANG Zuhong,SHI Qinglan,BAI Wenjie,et al.Professor MAO Dewen's experience in treating chronic liver disease with “Regulating liver and spleen”[J].,2021,(8):1112-1114,1119.[doi:DOI:10.3969/j.issn.1000-7369.2020.08.031]
点击复制

毛德文教授运用“调肝理脾”法治疗慢性肝病经验总结
分享到：

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2021年8期
页码:
1112-1114,1119
栏目:
名中医经验
出版日期:
2021-08-05

文章信息/Info

Title:
Professor MAO Dewen's experience in treating chronic liver disease with “Regulating liver and spleen”
作者:
黄祖鸿; 石清兰; 柏文婕; 韦华柱; 莫展进; 邓霖霖
(广西中医药大学,广西 南宁 530001)
Author(s):
HUANG Zuhong; SHI Qinglan; BAI Wenjie; WEI Huazhu; MO Zhanjin; DENG Linlin
(Guangxi University of Chinese Medicine,Nanning 530001,China)
关键词:
调肝理脾;  毛德文;  经验总结;  慢性肝病;  肝脾失调;  辨证论治
Keywords:
Regulating liver and spleen;  MAO Dewen;  Summary of experiences;  Chronic liver disease;  Liver-spleen disharmony;  Dialectical treatment
分类号:
R 249
DOI:
DOI:10.3969/j.issn.1000-7369.2020.08.031
文献标志码:
A
摘要:
慢性肝病进展缓慢,常常得不到患者足够的重视而造成复杂的病情甚至发展为肝衰竭。而肝、脾二脏在中医的生理、病理上相互作用,相互影响,在现代医学研究当中亦被证明二者息息相关。毛德文教授在长期诊治肝病的过程当中,强调了慢性肝病作为肝病的早期发展阶段更应尽早干预。他认为肝脾不和与慢性肝病关系密切,慢性肝病的核心病机是肝脾功能失调,其基本治疗原则为调和肝脾。而调肝理脾法属于中医治疗八大法之“和法”的范畴,其指导下的“培土涵木法”与“抑木扶土法”用于治疗慢性肝病能取得较好的临床疗效。本文试从调肝理脾的理论基础及临床应用两大方面介绍毛德文教授治疗慢性肝病的丰富经验。
Abstract:
The progress of the chronic liver disease is slow,often not enough attention of patients,resulting in complex disease and even develop into liver failure.The liver and spleen are closely related to the physiology and pathology of traditional Chinese medicine.In modern medical research,it has been proved that the two are closely related.In the process of long-term diagnosis and treatment of liver disease,professor MAO Dewen emphasized that chronic liver disease,as an early stage of liver disease development,should be intervened as soon as possible.He believe that chronic liver disease has close correlation with liver-spleen disharmony,the core pathogenesis of chronic liver disease is liver-spleen disharmony,and the basic treatment principle is to harmonize the liver and spleen.Regulating liver and spleen belongs to the category of “harmony method” of eight methods of TCM.It can obtain better clinical effect in the treatment of chronic liver disease with earth-reinforcing and wood-reducing method and soil-cultivating and wood-nourishing method.This article attempts to introduce Professor MAO's extensive experience in treating chronic liver disease from the theoretical basis and clinical application of regulating liver and spleen.

参考文献/References:

[1] 中华医学会感染病学分会肝衰竭与人工肝学,中华医学会肝病学分会重型肝病与人工肝学.肝衰竭诊治指南(2018年版)[J].临床肝胆病杂志,2019,35(1):38-44.
[2] 毛德文.肝衰竭毒邪病因学说辨析[J].中医药导报,2007,13(1):8-11.
[3] 唐秋媛,龙富立,覃艳新,等.毛德文肝衰竭毒邪-毒浊学说及其临床应用拾遗[J].辽宁中医杂志,2019,46(12):2513-2515.
[4] 王 冰.黄帝内经[M].北京:中医古籍出版社,2003:315-316.
[5] 张锡纯.医学衷中参西录[M].石家庄:河北科学技术出版社,1985:552.
[6] 韩美林,龚振华.肠道菌群在肝胆疾病中的作用机制[J].临床肝胆病杂志,2017,33(2):384-388.
[7] 冯锦凯,陈振华,武宇轩,等.肠道菌群在慢性肝病和肝细胞癌中的作用及临床意义[J].第二军医大学学报,2020,41(11):1246-1249.
[8] 陈晖娟,龚 慧,高江苓,等.肠道菌群与常见慢性肝病关系的研究进展[J].结直肠肛门外科,2020,26(4):414-417,422.
[9] 陈 斌,徐嘉蔚,彭 杰,等.基于逍遥散及其拆方研究“肝病实脾法”对肝纤维化大鼠肠道菌群的影响[J].临床肝胆病杂志,2016,32(4):657-662.
[10] 张 欢,孙劲晖.基于肠道微生态探索“调肝理脾”法治疗酒精性肝病的新思路[J].中国医药导报,2020,17(9):123-126.
[11] 陈瑞琳,申青艳,牛柯敏,等.调肝理脾法对非酒精性脂肪性肝病大鼠模型肠黏膜Toll样受体4、occludin表达的影响[J].临床肝胆病杂志,2019,35(10):2252-2256.
[12] 李长新,周 滔,牛柯敏,等.调肝理脾法对大鼠非酒精性脂肪性肝病脂质代谢和自噬相关蛋白-1表达的影响[J].中西医结合肝病杂志,2018,28(5):290-293,322.
[13] 郑彩翊.治未病在肿瘤方面的研究现状与策略[J].现代养生,2016,37(24):47-48.
[14] 蒋海南,毛德文,叶倩伶,等.中医辨证论治肝性脑病研究进展[J].陕西中医,2020,41(11):1678-1680.
[15] 蔡媛媛,蔡 敏,程亚伟.蔡敏教授运用调肝一方治疗非酒精性脂肪肝经验总结[J].陕西中医,2019,40(9):1275-1277.
[16] 银艳桃,王建超,廖 娟,等.疏肝健脾方联合恩替卡韦片治疗乙肝肝硬化肝郁脾虚证患者的临床研究[J].中药药理与临床,2020,36(4):187-191.
[17] 周 强,张声生.从调肝理脾论治非酒精性脂肪性肝病[J].世界中医药,2015,10(5):687-689.
[18] 王贵强,王福生,庄 辉,等.慢性乙型肝炎防治指南(2019年版)[J].临床肝胆病杂志,2019,35(12):2648-2669.
[19] 张超伟,张 钰,苏 珊,等.茯苓类药材本草学、化学成分和药理作用研究进展[J].湖北农业科学,2021,60(2):9-14,19.
[20] 谢爱泽,毛德文,石清兰,等.黄连温胆汤治疗慢性乙型肝炎肝纤维化肝胆湿热证的效果观察[J].临床肝胆病杂志,2020,36(7):1502-1507.
[21] 张慧贤,马向明,付庆江,等.肝细胞癌患者血清IL-17细胞因子水平检测的临床意义[J].陕西医学杂志,2016,45(10):1394-1395.
[22] 胡操寒.柴芍六君汤治疗肝郁脾虚型慢性乙型肝炎疗效观察[J].上海中医药杂志,2013,47(2):53-54.
[23] 樊海燕,刘晓莺.外周血T细胞亚群及Th17细胞/Treg细胞比值在乙肝病毒感染者诊断中的价值[J].陕西医学杂志,2016,45(10):1387-1389.
[24] 柏文婕,石清兰,毛德文,等.柴芍六君汤对慢性乙型肝炎肝郁脾虚证患者肝纤维化相关指标改善作用以及血清Treg/Th17比率变化的影响[J].中国中医基础医学杂志,2019,25(8):1111-1114,1122.

相似文献/References:

[1]蔡媛媛,蔡 敏△,程亚伟.蔡敏教授运用调肝一方治疗非酒精性脂肪肝经验总结*[J].陕西中医,2019,(9):1275.

备注/Memo

备注/Memo:
基金项目:国家自然科学基金资助项目(81760849,82060847); 广西中医药大学一流学科建设开放课题(2019XK022); 广西中医药大学2020年博士研究生科研创新项目(BS008)
更新日期/Last Update: 2021-08-09