[1]冯鹏超,赵汉清,冯鹏飞,等.小续命汤加减联合醒脑平衡法针刺治疗脑卒中恢复期临床研究[J].陕西中医,2021,(8):1124-1127.[doi:DOI:10.3969/j.issn.1000-7369.2020.08.034]
 FENG Pengchao,ZHAO Hanqing,FENG Pengfei,et al.Clinical observation of Xiaoxuming decoction combined with Xingnao balance acupuncture in the treatment of convalescent stroke patients[J].,2021,(8):1124-1127.[doi:DOI:10.3969/j.issn.1000-7369.2020.08.034]
点击复制

小续命汤加减联合醒脑平衡法针刺治疗脑卒中恢复期临床研究

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2021年8期
页码:
1124-1127
栏目:
针灸经络
出版日期:
2021-08-05

文章信息/Info

Title:
Clinical observation of Xiaoxuming decoction combined with Xingnao balance acupuncture in the treatment of convalescent stroke patients
作者:
冯鹏超赵汉清冯鹏飞樊丽霞梁进凤周利飞
(河北北方学院附属第二医院,河北 张家口 075100)
Author(s):
FENG PengchaoZHAO HanqingFENG PengfeiFAN LixiaLIANG JinfengZHOU Lifei
(The Second Affiliated Hospital of Hebei North University,Zhangjiakou 075100,China)
关键词:
脑卒中 恢复期 小续命汤 醒脑平衡法针刺 脑源性神经营养因子 神经元特异性烯醇化酶
Keywords:
Stroke Convalescent period Xiaoxuming decoction Xingnao balance acupuncture Brain-derived neurotrophic factor Neuron specific enolase
分类号:
R 743.3
DOI:
DOI:10.3969/j.issn.1000-7369.2020.08.034
文献标志码:
A
摘要:
目的:观察小续命汤加减联合醒脑平衡法针刺对脑卒中恢复期患者的临床疗效。方法:选取186例脑卒中恢复期患者按照随机数字表法分为中药组和针药组。中药组予小续命汤中药汤剂治疗,针药组在中药组基础上加用醒脑平衡法针刺治疗。两组疗程均为3周。观察并记录两组患者治疗前后卒中量表(NIHSS)评分、Fugl-Meyer评分及神经功能指标脑源性神经营养因子(BDNF)、神经元特异性烯醇化酶(NSE)、神经营养因子(NGF)水平、中医症候积分及临床疗效。结果:与中药组比较,针药组NIHSS评分、中医症候积分,NSE水平均较低(P<0.05)。与中药组比较,针药组Fugl-Meyer评分,BDNF、NGF水平,治疗总有效率均较高(P<0.05)。结论:在小续命汤基础上加用脑平衡法针刺干预脑卒中恢复期可改善患者神经功能、运动功能及中医症候情况。
Abstract:
Objective:To observe the clinical effect of Xiaoxuming decoction combined with Xingnao balance acupuncture on stroke patients in convalescence.Methods:186 stroke patients were randomly divided into traditional Chinese medicine group and acupuncture group,93 cases in each group.The traditional Chinese medicine group was treated with Xiaoxuming decoction,while the acupuncture medicine group was treated with Xingnao balance acupuncture on the basis of the traditional Chinese medicine group.Both groups were treated for 3 weeks.The NIHSS score,Fugl Meyer score,brain-derived neurotrophic factor(BDNF),neuron specific enolase(NSE),neurotrophic factor(NGF),TCM syndrome score and clinical efficacy were observed and compared between the two groups before and after treatment.Results:Compared with the traditional Chinese medicine group,the NIHSS score,TCM syndrome score and NSE level of the acupuncture and medicine group were lower(P<0.05).Compared with the traditional Chinese medicine group,the Fugl meyer score,BDNF,NGF levels and the total effective rate of the acupuncture and medicine group were higher(P<0.05).Conclusion:On the basis of Xiaoxuming decoction,acupuncture with brain balance method can improve the neurological function,motor function and TCM syndrome of stroke patients.

参考文献/References:

[1] Das AS,Regenhardt RW,Feske SK,et al.Treatment approaches to lacunar stroke[J].J Stroke Cerebrovasc Dis,2019,28(8):2055-2078.
[2] 张锡萍,张斐雪,郑书林,等.血栓通联合吡拉西坦对缺血性脑卒中患者中医症候评分、神经功能及血清NPY、Hcy水平的影响[J].陕西中医,2021,42(3):326-329.
[3] 龚 柳,王 宇,姚迎叶,等.基于社区的非急性期缺血性脑卒中患者健康状态和中医特征调查[J].中国中西医结合杂志,2019,39(12):1434-1439.
[4] 许玲玲,张燕儿,曹建平.小醒脑针法联合康复措施治疗缺血性脑卒中恢复期偏瘫临床研究[J].新中医,2019,51(8):241-243.
[5] 武晓磊,冯学功.醒脑平衡针刺法治疗急性缺血性脑卒中患者的临床观察[J].世界中医药,2019,14(6):1577-1580,1585.
[6] 中华医学会神经病学分会,中华医学会神经病学分会脑血管病学组.中国急性缺血性脑卒中诊治指南2018[J].中华神经科杂志,2018,51(9):666-682.
[7] 程 雪,都文渊,王媛媛,等.《中风病辨证诊断标准》在中风病急性期的应用[J].中国中医急症,2013,22(9):1527-1529.
[8] 李丽容,卢治兰,邓向海,等.2型糖尿病患者并发缺血性脑卒中危险因素及与载脂蛋白E基因型相关性分析[J].陕西医学杂志,2021,50(6):723-725,730.
[9] 吕晓丽.益气化风祛痰通络方治疗对缺血性脑卒中恢复期患者肌力、神经功能生活能力的影响[J].中国中医药科技,2020,27(5):812-814.
[10] 李 莉,孙海洋,郭雁玲.小续命汤加减治疗急性缺血性脑卒中(风火上扰证)的疗效分析[J].中国中医急症,2020,29(4):683-686.
[11] 郭捷婷,朱根福.小续命汤加减治疗急性缺血性中风疗效观察[J].西部中医药,2019,32(7):99-102.
[12] 陈 静,陈 炜,伍 媛,等.小续命汤及其组分治疗急性脑梗死研究进展[J].陕西中医,2019,40(12):1818-1821.
[13] 朱静嫣,周 叶.小续命汤治疗急性缺血性脑卒中的卫生经济学评价[J].中西医结合心脑血管病杂志,2020,18(22):3862-3864.
[14] 杨 辉,唐世球,邵方玲.肾脑复元汤联合醒脑开窍针刺法用于缺血性中风的临床观察[J].世界中西医结合杂志,2020,15(1):160-164,169.
[15] 苗志凯,王 艳,夏清岫.醒脑开窍针刺法对急性脑出血患者微创血肿清除术后神经功能、MMPS及Cysc的影响[J].中国中医急症,2020,29(7):1172-1175.
[16] 罗 莹,王彦红.醒脑开窍针刺法治疗前庭性偏头痛[J].长春中医药大学学报,2020,36(1):113-115.
[17] 张 琦,田朝霞.醒脑开窍针刺法联合阿替普酶对急性脑梗死患者神经功能缺损、脂质过氧化及脑血管储备功能的影响[J].上海针灸杂志,2020,39(1):25-30.
[18] 王爱丽,王 倩.补阳还五汤联合丹红注射液对缺血性脑卒中气虚血瘀证神经功能及血清神经生长因子、脑源性神经细胞营养因子的影响[J].陕西中医,2019,40(6):692-695.
[19] 孙淑婷.益气活血方对脑卒中恢复期病人神经功能和血清NSE水平的影响[J].中西医结合心脑血管病杂志,2020,18(16):2695-2697.
[20] 赵 璇,李媛洁.雌性老年大鼠部分脑区NGF、BDNF、Trk A和Trk B表达的变化[J].陕西医学杂志,2012,41(3):285-288.
[21] 赵俊朝.温阳化瘀汤联合醒脑开窍针刺法对脑梗死恢复期患者神经功能及运动功能的影响[J].河南中医,2020,40(10):1610-1613.

相似文献/References:

[1]金硕果,尹海燕,孙鸿辉△,等.三七对轻型缺血性脑卒中患者“双抗”治疗后出血事件影响的研究*[J].陕西中医,2019,(3):287.
 JIN Shuoguo,YIN Haiyan,SUN Honghui,et al.Impact study of Panax notoginseng on hemorrhagic event after treatment of dual antiplatelet therapy in patients with acute minor stroke[J].,2019,(8):287.
[2]张子英,吴伯涛,翟清华.益气活血法与化痰通络疗法对脑卒中症状治疗的应用价值探讨[J].陕西中医,2019,(2):250.
[3]樊锐敏.肝胃百合汤对脑卒中肠内营养患者胃肠道反应的影响[J].陕西中医,2019,(1):52.
 FAN Ruimin..Effect of Ganwei Baihe decoction on gastrointestinal reaction in patients with cerebral apoplexy enteral nutrition[J].,2019,(8):52.
[4]常雪利.针灸治疗对脑卒中后偏瘫颈肩痛患者疼痛改善及预后的影响*[J].陕西中医,2019,(4):525.
 CHANG Xueli..Analysis of the effect of acupuncture on pain improvement and prognosis in patients with hemiplegia neck shoulder and pain[J].,2019,(8):525.
[5]许文杰,蒋瑞冲,周一心,等.王翘楚教授经验方治疗肝郁瘀阻型脑卒中后失眠临床研究*[J].陕西中医,2019,(7):867.
 XU Wenjie,Jiang Ruichong,Zhou Yixin,et al.Therapeutic observation of experience prescription in party of professor Wang Qiaochu for post-stroke insomnia due to liver depression and blood stasis bolck[J].,2019,(8):867.
[6]罗 玮,李 耘,刘 玲.加味涤痰汤治疗卒中后抑郁疗效及对患者外周血NF-κB、miR-146a表达的影响[J].陕西中医,2019,(8):1029.
 LUO Wei,LI Yun,LIU Ling..Clinical effect of Jiawei Ditan decoction on post-stroke depressionand the expression of NF-κB and miR-146a in peripheral blood[J].,2019,(8):1029.
[7]蒋 岚,田慧军△,黄 伟.针灸联合黛力新治疗脑卒中后抑郁疗效及对患者血清神经递质水平的影响[J].陕西中医,2019,(8):1134.
 JIANG Lan,TIAN Huijun,HUANG Wei..Effects of Acupuncture combined with Deanxit on Post-stroke depression and its influence on serum neurotransmitters level[J].,2019,(8):1134.
[8]萨仁,李长君,蔡海鑫.头穴丛刺对脑卒中后血管性痴呆患者认知功能及血清HIF1α的影响*[J].陕西中医,2019,(11):1622.
 SA Ren,LI Changjun,CAI Haixin..Effect of scalp acupuncture on cognitive function and serum HIF1α in patients with vascular dementia after stroke[J].,2019,(8):1622.
[9]王 佳 ,沈卫东△.头针、舌针联合康复训练治疗脑卒中后吞咽障碍疗效研究*[J].陕西中医,2019,(12):1774.
 WANG Jia,SHEN Weidong..Efficacy of scalp acupuncture and tongue acupuncture combined with rehabilitation training on dysphagia after cerebral stroke[J].,2019,(8):1774.
[10]刘兰兰,耿翊宁.经穴针刺对老年脑卒中患者脑灌注及血小板反应蛋白1水平影响研究[J].陕西中医,2019,(12):1778.
 LIU Lanlan,GENG Yining..Effect of acupoint acupuncture on cerebral perfusion and thrombospondin 1 in senile patients with stroke[J].,2019,(8):1778.

备注/Memo

备注/Memo:
基金项目:科技部十三五重点研发计划项目(2017YFC1307701); 河北省中医药管理局科研计划项目(2020239)
更新日期/Last Update: 2021-08-09