[1]郑俊佳,黄 彬,郭绍举,等.疏肝和胃法治疗胆汁反流性胃炎临床疗效和安全性Meta分析[J].陕西中医,2022,(11):1638-1642.[doi:DOI:10.3969/j.issn.1000-7369.2022.11.035]
　ZHENG Junjia,HUANG Bin,GUO Shaoju,et al.Meta-analysis of clinical efficacy and safety of Shugan Hewei therapy for bile reflux gastritis[J].,2022,(11):1638-1642.[doi:DOI:10.3969/j.issn.1000-7369.2022.11.035]
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疏肝和胃法治疗胆汁反流性胃炎临床疗效和安全性Meta分析
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2022年11期
页码:
1638-1642
栏目:
Meta分析
出版日期:
2022-11-05

文章信息/Info

Title:
Meta-analysis of clinical efficacy and safety of Shugan Hewei therapy for bile reflux gastritis
作者:
郑俊佳1; 黄 彬2; 郭绍举2; 李海文2; 李娟娟2; 陈玉意1; 陈 楠1; 王洪亮1
(1.广州中医药大学第四临床医学院,广东 深圳 518033; 2.深圳市中医院脾胃科,广东 深圳 518033)
Author(s):
ZHENG Junjia; HUANG Bin; GUO Shaoju; LI Haiwen; LI Juanjuan; CHEN Yuyi; CHEN Nan; WANG Hongliang
(The Fourth Affiliated Hospital of Guangzhou University of Chinese Medicine,Shenzhen 518033,China)
关键词:
胆汁反流性胃炎;  疏肝和胃法;  柴胡疏肝散;  总有效率;  安全性;  Meta分析
Keywords:
Bile reflux gastritis;  Shugan Hewei therapy;  Chaihu Shugan powder;  Total effective rate;  Safety;  Meta-analysis
分类号:
R 573.3
DOI:
DOI:10.3969/j.issn.1000-7369.2022.11.035
文献标志码:
A
摘要:
目的:通过Meta分析系统评价疏肝和胃法治疗胆汁反流性胃炎临床疗效与安全性。方法:检索中国知网、万方、中国生物医学文献数据库、维普、Pub Med电子数据库所有关于疏肝和胃法治疗胆汁反流性胃炎的临床随机对照实验; 文献筛选、数据提取后,应用Rev Man 5.3软件对符合标准的文献进行Meta分析。结果:共纳入15项研究,1249例患者,试验组总有效率[RR=1.24,95%CI(1.18,1.31),P<0.01]、胃镜下有效率[RR=1.14,95%CI(1.05,1.23),P<0.01]均高于对照组。试验组复发率低于对照组[RR=0.38,95%CI(0.25,0.56),P<0.01]。两组均无严重不良反应发生。结论:疏肝和胃法治疗胆汁反流性胃炎总有效率、胃镜下有效率、复发率均优于常规西药治疗,且具有较好的安全性。
Abstract:
Objective:To evaluate the clinical efficacy and safety of Shugan Hewei therapy in the treatment of bile reflux gastritis by Meta-analysis.Methods:All clinical randomized controlled trials on Shugan Hewei therapy in the treatment of bile reflux gastritis were searched from CNKI,Wanfang,China Biology Medicine disc,VIP,Pub Med and other electronic databases.After literature screening and data extraction,Rev Man 5.3 software was used to perform Meta-analysis on the literatures meeting the criteria.Results:A total of 15 studies involving 1249 patients were included.The total effective rate [RR=1.24,95%CI(1.18,1.31),P<0.01] and the effective rate under gastroscope [RR=1.14,95%CI(1.05,1.23),P<0.01] of experimental group were higher than those of control group.The recurrence rate of experimental group was lower than that of control group [RR=0.38,95%CI(0.25,0.56),P<0.01].No serious adverse reactions occurred in the two groups.Conclusion:The total effective rate,the effective rate under gastroscope and the recurrence rate of the treatment of bile reflux gastritis by Shugan Hewei therapy are better than those by conventional western medicine,and have good safety.

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金资助项目(82104747); 广东省基础与应用基础研究基金资助项目(2020A1515110947)
更新日期/Last Update: 2022-11-09