[1]郭泽春,姜 燕,郑 峰,等.急性后循环脑梗死患者椎动脉颅内段钙化特征与中医体质分型相关性研究[J].陕西中医,2023,(9):1212-1215.[doi:DOI:10.3969/j.issn.1000-7369.2023.09.012]
　GUO Zechun,JIANG Yan,ZHENG Feng,et al.Study on the correlation between the characteristics of intracranial vertebral artery calcification and TCM constitution classification in patients with acute posterior circulation cerebral infarction[J].,2023,(9):1212-1215.[doi:DOI:10.3969/j.issn.1000-7369.2023.09.012]
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急性后循环脑梗死患者椎动脉颅内段钙化特征与中医体质分型相关性研究

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2023年9期
页码:
1212-1215
栏目:
临床研究
出版日期:
2023-09-05

文章信息/Info

Title:
Study on the correlation between the characteristics of intracranial vertebral artery calcification and TCM constitution classification in patients with acute posterior circulation cerebral infarction
作者:
郭泽春1; 姜 燕2; 郑 峰2; 闫 瑾3; 柳淑青1; 袁 杰1; 李佳勇1; 许长敏1
(1.北京中医医院顺义医院神经内科,北京 101300; 2.上海中医药大学继续教育学院,上海 201203; 3.北京中医医院顺义医院康复科,北京101300)
Author(s):
GUO Zechun; JIANG Yan; ZHENG Feng; YAN Jin; LIU Shuqing; YUAN Jie; LI Jiayong; XU Changmin
(Department of Neurology,Shunyi Hospital,Beijing Hospital of Traditional Chinese Medicine,Beijing 101300,China)
关键词:
急性后循环脑梗死;  椎动脉颅内段;  钙化特征;  中医体质分型;  相关性分析;  危险因素分析
Keywords:
Acute posterior circulation cerebral infarction;  Intracranial segment of vertebral artery;  Calcification characteristics;  TCM constitution classification;  Correlation analysis;  Risk factor analysis
分类号:
R 743.34
DOI:
DOI:10.3969/j.issn.1000-7369.2023.09.012
文献标志码:
A
摘要:
目的:分析急性后循环脑梗死(APCCI)患者椎动脉颅内段(IVA)钙化特征与中医体质分型相关性研究。方法:选择100例急性脑血管疾病患者,所有患者均进行椎动脉及颅脑CT检查,并分成APCCI组(n=50)、非APCCI组(n=50),对比两组IVA钙化情况,并分析APCCI患者中医体质分布规律; 对比不同中医体质分型APCCI患者IVA钙化情况,采用Spearman分析APCCI患者IVA钙化特征与中医体质分型的相关性; 进一步比较两组临床指标,并采用多因素回归分析法分析影响APCCI患者IVA钙化的危险因素。结果:APCCI患者IVA钙化率明显高于非APCCI患者; APCCI患者常见的中医体质为痰湿质、气虚质,分别占比32.00%、28.00%; 不同中医体质分型的APCCI患者IVA钙化情况不同或不完全相同; 而Spearman分析发现APCCI患者中医体质分型与IVA钙化存在一定相关性(r=0.413,P<0.05); 钙化组UA、HDL-C、ALP高于无钙化组(P<0.05),两组在年龄、性别、吸烟情况、基础病史等方面比较差异无统计学意义(P>0.05); 经Logistic回归分析发现,UA、ALP、HDL-C是影响APCCI患者IVA钙化的确切性风险因素。结论:APCCI患者IVA钙化与中医体质分型有一定相关性,且影响APCCI患者IVA钙化的因素较多,需进一步加强APCCI防治工作。
Abstract:
Objective:To analyze the correlation between vertebral artery intracranial segment(IVA)calcification and TCM constitution classification in patients with acute posterior circulation cerebral infarction(APCCI).Methods:A total of 100 patients with acute cerebrovascular diseases were selected.All patients underwent vertebral artery and craniocerebral CT examination,and were divided into APCCI group(n=50)and non-APCCI group(n=50).IVA calcification in the two groups was compared and analyzed.The distribution law of TCM constitution of APCCI patients was analyzed.According to the IVA calcification of APCCI patients,they were divided into calcification group and non-calcification group.The IVA calcification of APCCI patients with different TCM constitution types was compared,and the correlation between the IVA calcification characteristics of APCCI patients and TCM constitution types was analyzed by Spearman.The clinical indicators of the two groups were further compared and the risk factors of IVA calcification in APCCI patients were analyzed by multivariate regression analysis.Results:The rate of IVA calcification in APCCI patients was significantly higher than that in non-APCCI patients.The common constitutions of TCM in APCCI patients were phlegm-dampness and qi-deficiency,accounting for 32.00% and 28.00% respectively.IVA calcification of APCCI patients with different TCM constitution types was different or not identical; Spearman analysis found that there was a correlation between TCM constitution classification and IVA calcification in APCCI patients(r=0.413,P<0.05).The UA,HDL-C and ALP of the calcification group were higher than those of the non-calcification group(P<0.05),and there were no statistically significant differences in age,sex,smoking status and basic medical history between the two groups(P>0.05).Logistic regression analysis showed that UA,ALP and HDL-C were the exact risk factors affecting IVA calcification in APCCI patients.Conclusion:IVA calcification in APCCI patients has a certain correlation with traditional Chinese medicine constitution classification,and there are many factors affecting IVA calcification in APCCI patients,so the prevention and treatment of APCCI should be further strengthened.

参考文献/References:

[1] 段国华,叶秋菊,张海燕,等.川芎龙蛭汤联合耳穴电探测贴压治疗脑梗死气虚血瘀证临床研究[J].陕西中医,2022,43(9):1200-1203.
[2] 王 东,范玲玲,徐东为,等.两种不同分型胚胎型大脑后动脉对急性后循环脑梗死的影响研究[J].陕西医学杂志,2021,50(1):51-54.
[3] 吴福佳,杨小英,李建橡,等.高血压前期人群中医体质分布特点及与血尿酸水平的相关性研究[J].现代中西医结合杂志,2021,30(19):2068-2071.
[4] 高冰心,张 艳,李小盼,等.椎动脉优势患者双侧血流差异分析对后循环梗死的预测价值研究[J].中国超声医学杂志,2022,38(2):209-213.
[5] 刘星辰,吴健恒,彭慧渊,等.重型急性缺血性卒中合并癫痫发作患者的中医证型与视频脑电图表现的相关性研究[J].中国中医急症,2022,31(8):1175-1178.
[6] 周映彤,邹达良,赵 敏,等.老年人良性阵发性位置性眩晕复位后复发危险因素及中医体质相关性研究[J].医学临床研究,2021,38(4):589-591.
[7] 杜茜茜,杨 铭.醒脑开窍针刺法联合西医常规治疗对糖尿病合并亚急性期脑梗死患者神经功能、血脂、炎症因子及血糖的影响[J].陕西中医,2021,42(4):523-526.
[8] 中国后循环缺血专家共识组.中国后循环缺血的专家共识[J].中华内科杂志,2006,45(9):786-787.
[9] 刘四军,周成成.《中医体质分类与判定表》的简化研究[J].广州中医药大学学报,2021,38(8):1734-1739.
[10] Zhao Y,Han Y.Clinical symptoms,etiology and prognosis of acute bilateral posterior circulation cerebral infarction[J].Int J Gen Med,2022,15:2787-2793.
[11] 罗星星,雷 励,蒲云学.活血醒脑复原汤对急性后循环脑梗死患者的临床综合评价[J].中国中医急症,2022,31(4):634-637.
[12] 张雄智.阿加曲班联合依达拉奉对后循环急性脑梗死患者神经功能恢复及血清Hcy、CXCL16和TGF-β1的影响[J].中国动脉硬化杂志,2021,29(8):695-701.
[13] 陈 鹏,韦 寅,邱维加,等.颅内动脉钙化定量评价与脑小血管病总体负担评分的相关性研究[J].医学影像学杂志,2022,32(6):911-915.
[14] 郑锐标,吕永革,李超军,等.颈内动脉颅内段钙化与缺血性脑小血管病影像学相关性研究[J].实用放射学杂志,2022,38(7):1053-1056.
[15] 边祥兵,林家骥,张森皓,等.颅内椎-基底动脉夹层形态学与后循环缺血程度的相关性研究[J].中国卒中杂志,2021,16(5):440-445.
[16] 彭大伟,罗 艺,朱 丽,等.后循环缺血性脑卒中患者颅内椎基底动脉钙化的影像征象[J].四川医学,2022,43(12):1174-1178.
[17] 高亚军,张 欢,师 强,等.急性脑梗死患者颈动脉狭窄程度与颈动脉易损斑块MRI特征关系研究[J].陕西医学杂志,2022,51(9):1094-1097.
[18] 阳飞燕,张小红,黄 珊,等.418例绝经后脑梗死患者中医体质与危险因素相关性研究[J].中国中医急症,2022,31(8):1143-1146.
[19] 张 洋,王丽娜,朱良付,等.椎动脉颅内段急性闭塞临床影像特征及血管内治疗效果观察[J].中国脑血管病杂志,2023,20(1):1-9.
[20] 金泉伟,邹兴菊.氯吡格雷联合奥扎格雷钠治疗后循环脑梗死对患者血液流变学、NIHSS评分、Barthel指数及血清炎症因子的影响[J].陕西医学杂志,2021,50(2):225-228,232.

备注/Memo

备注/Memo:
基金项目:国家自然科学基金资助项目(81804090); 北京市属医院科研培育计划项目(PZ2023023)
更新日期/Last Update: 2023-09-08