[1]孙 伟,孙秋月,徐 淼.养心平脉汤配合针灸治疗气阴两虚兼血瘀型胸痹心痛疗效及对患者中医症状、心电图指标的影响[J].陕西中医,2023,(9):1308-1311.[doi:DOI:10.3969/j.issn.1000-7369.2023.09.036]
　SUN Wei,SUN Qiuyue,XU Miao.Effects of Yangxin Pingmai decoction combined with acupuncture and moxibustion on TCM symptoms and electrocardiogram indicators in treating chest stuffiness and pains(qi-yin deficiency and blood stasis type)[J].,2023,(9):1308-1311.[doi:DOI:10.3969/j.issn.1000-7369.2023.09.036]
点击复制

养心平脉汤配合针灸治疗气阴两虚兼血瘀型胸痹心痛疗效及对患者中医症状、心电图指标的影响
分享到：

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2023年9期
页码:
1308-1311
栏目:
针灸经络
出版日期:
2023-09-05

文章信息/Info

Title:
Effects of Yangxin Pingmai decoction combined with acupuncture and moxibustion on TCM symptoms and electrocardiogram indicators in treating chest stuffiness and pains(qi-yin deficiency and blood stasis type)
作者:
孙 伟; 孙秋月; 徐 淼
(衡水市中医医院内分泌肾病一科,河北 衡水 053000)
Author(s):
SUN Wei; SUN Qiuyue; XU Miao
(Department of Endocrinology and Nephropathy,Hengshui Hospital of Traditional Chinese Medicine,Hengshui 053000,China)
关键词:
胸痹心痛;  气阴两虚兼血瘀型;  养心平脉汤;  针灸;  心电图ST-T指标;  血管内皮功能;  心功能
Keywords:
Chest stuffiness and pains;  Qi-yin deficiency and blood stasis type;  Yangxin Pingmai decoction;  Acupuncture and moxibustion;  Electrocardiogram ST-T indicators;  Vascular endothelial function;  Cardiac function
分类号:
R 541.4
DOI:
DOI:10.3969/j.issn.1000-7369.2023.09.036
文献标志码:
A
摘要:
目的:探究养心平脉汤配合针灸治疗气阴两虚兼血瘀型胸痹心痛的临床疗效及对患者中医症状积分和心电图指标的影响。方法:79例慢性稳定型心绞痛患者随机分为治疗组40例,对照组39例。两组均予西药基础治疗,对照组加针灸治疗,治疗组在针灸治疗基础上,加予养心平脉汤,两组均治疗8周。比较两组临床疗效。比较两组中医症状积分、心电图ST-T指标、心功能、血管内皮功能指标变化及不良反应。结果:治疗后,治疗组临床总有效率显著高于对照组(P<0.05); 观察组中医症状积分,心电图ST-T段压低最大值、压低导联数及LVESD、LVEDD均较治疗前下降且低于对照组(P<0.05),LVEF、CI均较治疗前升高且高于对照组(P<0.05); 两组均未见明显不良反应。结论:养心平脉汤配合针灸可提高气阴两虚兼血瘀型胸痹心痛患者临床疗效,改善患者症状及血管内皮功能,促进心功能恢复。
Abstract:
Objective:To explore the clinical efficacy of Yangxin Pingmai decoction combined with acupuncture and moxibustion in the treatment of qi-yin deficiency and blood stasis type of chest stuffiness and pains(angina pectoris)and its influence on TCM symptoms scores and electrocardiogram indicators.Methods:79 patients chronic stable angina pectoris were divided into treatment group(40 cases)and control group(39 cases).Both groups were given basic western medicine therapy,and the control group was added with acupuncture and moxibustion while the treatment group was given Yangxin Pingmai decoction on the basis of acupuncture and moxibustion.Both groups were treated for 8 weeks.The clinical efficacy and changes of TCM symptoms scores,electrocardiogram ST-T indicators,cardiac function indicator and vascular endothelial function indicators were compared between the two groups,and the adverse reactions of the two groups during treatment were recorded.Results:After treatment,the clinical effective rate in treatment group was significantly higher than that in control group(P<0.05).In the observation group,the traditional Chinese medicine symptom scores,the maximum depression of the electrocardiogram ST-T segment,the number of depressed leads,LVESD and LVEDD were all decreased compared to before treatment and were lower than the control group(P<0.05).The LVEF and CI were both increased compared to before treatment and were higher than the control group(P<0.05).No obvious adverse reactions were observed in both groups.Conclusion:Yangxin Pingmai decoction combined with acupuncture and moxibustion can enhance the clinical efficacy of chest stuffiness and pains of qi-yin deficiency and blood stasis type,improve the symptoms and vascular endothelial function,and promote the recovery of cardiac function.

参考文献/References:

[1] 陈 瑶,王 艳,薛 强,等.心痛舒治疗冠心病心绞痛的疗效及对肝肾功能的影响[J].中国老年学杂志,2022,42(9):2049-2052.
[2] 董 昕,杨朋康.单硝酸异山梨酯联合维拉帕米对冠心病稳定型心绞痛患者血脂水平及血清同型半胱氨酸、高敏C反应蛋白的影响[J].陕西医学杂志,2020,49(4):485-488.
[3] 李慧敏,熊兴江,赵 晖,等.近3年中医药治疗稳定型心绞痛随机对照试验结局指标的现状分析[J].北京中医药大学学报,2020,43(7):606-616.
[4] 李海啸,闫 磊.《玉机微义》胸痹虚证探析[J].陕西中医,2021,42(10):1439-1441.
[5] 巩昌镇,梁繁荣,李灿辉,等.对JAMA“针刺辅助治疗慢性稳定型心绞痛随机临床试验”一文的讨论[J].中国针灸,2021,41(4):359-364,370.
[6] 邱 敏,孙 科,陶 劲,等.《金匮要略》胸痹“阳微阴弦”病机探微[J].中国中医基础医学杂志,2017,23(2):151-152.
[7] 李 京,张明雪,金跟海.胸痹心痛中医学证机概要[J].中华中医药杂志,2014,29(8):2430-2432.
[8] 中华人民共和国卫生部.中药新药临床研究指导原则试行[M].北京:中国医药科技出版社,2002:361-390.
[9] 韩景波,陈卿倩,吕艳杭,等.化痰开痹汤对痰浊型难治性冠心病心绞痛患者疗效及Lp-PLA2、MCP-1、sICAM-1的影响[J].中国老年学杂志,2022,42(10):2327-2331.
[10] 俸道荣,韦 斌,曲 楠,等.瓜蒌薤白半夏汤合小建中汤加减治疗阳虚痰阻型稳定型心绞痛的临床研究[J].中华中医药杂志,2022,37(2):1184-1187.
[11] 夏哲林,章 欣,金礼通,等.麝香保心丸联合常规治疗对冠心病稳定型心绞痛患者的临床疗效[J].中成药,2021,43(7):1772-1774.
[12] 孙秋月,夏梅华,闫茹玉.欣康胶囊治疗气阴两虚兼血瘀型胸痹心痛病疗效观察[J].现代中西医结合杂志,2022,31(7):960-963.
[13] 董良杰,王勤俭,王单一,等.少林八段锦锻炼联合益气凉血生肌方对老年冠心病患者PCI术后步行功能及LVESD、LVEDD等心功能的影响[J].中国老年学杂志,2022,42(2):322-325.
[14] 王 芳,陈 洁,刘宇涵,等.通心络胶囊联合倍他乐克对冠心病稳定型心绞痛患者心功能的影响[J].世界中医药,2021,16(17):2605-2610.
[15] 李 翔,赵琴琴,郑鸣之,等.黄芪甲苷和丹参素对大鼠心肌缺血后心功能的保护作用研究[J].中国现代应用药学,2021,38(18):2208-2214.
[16] 赵玉涵,肖光旭,范斯文,等.丹参-川芎药对治疗心脑血管疾病的作用机制及临床研究[J].中国动脉硬化杂志,2022,30(6):461-469.
[17] 刘 俊,周有利,潘云红,等.红花黄色素注射液对不稳定型心绞痛患者部分氧化应激和炎性因子水平的影响[J].贵州医科大学学报,2020,45(7):792-796.
[18] 钱承嗣,蒋 峻.注射用丹参多酚酸联合曲美他嗪治疗老年冠心病心绞痛患者疗效及对炎性因子、血管内皮损伤和血脂的影响[J].中国老年学杂志,2021,41(21):4614-4617.
[19] 柴娟娟,韩卫星,张松文.氯吡格雷联合依折麦布对冠心病心绞痛患者内皮功能及脂代谢的影响[J].中国临床药理学杂志,2021,37(1):12-15.
[20] 王 科,王琼芬,钟永强,等.炙甘草汤加五参颗粒联合西药治疗冠心病的临床疗效及其对患者血清hs-CRP、NT-proBNP水平和内皮功能的影响[J].现代生物医学进展,2019,19(3):494-497.
[21] 陈 军,谭德敏,蒙振发.丹参川芎嗪注射液联合双联抗血小板对不稳定型心绞痛患者细胞凋亡、斑块稳定性及血管内皮功能的影响[J].中国老年学杂志,2020,40(12):2477-2480.

相似文献/References:

[1]彭艳斌,蔡虎志,陈青扬,等.从“阳化气阴成形”理论探讨枳实薤白桂枝汤治疗胸痹*[J].陕西中医,2020,(12):1787.[doi:DOI:10.3969/j.issn.1000-7369.2020.12.028]
[2]肖 进,张新莉.醒脾祛湿汤治疗湿浊痹阻型胸痹心痛临床研究[J].陕西中医,2021,(4):463.[doi:DOI:10.3969/j.issn.1000-7369.2020.04.015]
　XIAO Jin,ZHANG Xinli.Clinical study on chest pain patients with Shizhuo Bizu type treated by Xingpi Qushi decoction[J].,2021,(9):463.[doi:DOI:10.3969/j.issn.1000-7369.2020.04.015]

备注/Memo

备注/Memo:
基金项目:河北省中医药管理局科研计划项目(2019339)
更新日期/Last Update: 2023-09-08