[1]王海锋,孟 怡,刘 青,等.厚朴排气合剂联合经皮穴位电刺激对产后抑郁合并胃肠功能障碍患者胃肠功能及抑郁情绪的影响[J].陕西中医,2024,(1):46-49,54.[doi:DOI:10.3969/j.issn.1000-7369.2024.01.010]
　WANG Haifeng,MENG Yi,LIU Qing,et al.Clinical observation on the effect of magnolia exhaust mixture combined with percutaneous acupoint electrical stimulation on postpartum depression complicated with gastrointestinal dysfunction[J].,2024,(1):46-49,54.[doi:DOI:10.3969/j.issn.1000-7369.2024.01.010]
点击复制

厚朴排气合剂联合经皮穴位电刺激对产后抑郁合并胃肠功能障碍患者胃肠功能及抑郁情绪的影响
分享到：

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2024年1期
页码:
46-49,54
栏目:
临床研究
出版日期:
2024-01-05

文章信息/Info

Title:
Clinical observation on the effect of magnolia exhaust mixture combined with percutaneous acupoint electrical stimulation on postpartum depression complicated with gastrointestinal dysfunction
作者:
王海锋1; 孟 怡1; 刘 青2; 景邵春3
(1.秦皇岛市第二医院产科,河北 秦皇岛066600; 2.秦皇岛市第二医院肾内科,河北 秦皇岛066600; 3.秦皇岛市第二医院创伤关节科,河北 秦皇岛066600)
Author(s):
WANG Haifeng; MENG Yi; LIU Qing; JING Shaochun
(Department of Obstetrics,Qinhuangdao Second Hospital,Qinhuangdao 066600,China)
关键词:
产后抑郁;  胃肠功能障碍;  腹胀;  厚朴排气合剂;  经皮穴位电刺激;  不良反应
Keywords:
Postpartum depression;  Gastrointestinal dysfunction;  Abdominal distension;  Magnolia exhaust mixture;  Transcutaneous acupoint electrical stimulation;  Adverse reactions
分类号:
R 714.6
DOI:
DOI:10.3969/j.issn.1000-7369.2024.01.010
文献标志码:
A
摘要:
目的:探讨厚朴排气合剂联合经皮穴位电刺激对产后抑郁合并胃肠功能障碍的临床效果。方法:将120例产后抑郁合并胃肠功能障碍患者随机分为观察组(n=60)和对照组(n=60)。对照组给予经皮穴位电刺激治疗,观察组给予厚朴排气合剂联合经皮穴位电刺激治疗,疗程均为7 d。比较两组患者胃肠功能恢复情况、胃肠道障碍症状评分、胃泌素(GAS)、胃动素(MTI)、腹胀发生率、腹胀程度、汉密尔顿抑郁量表评分以及不良反应发生情况。 结果:与对照组相比,观察组患者的肠鸣音恢复、首次肛门排气、首次排便、总住院时间明显更短(P<0.05)。治疗后,两组患者胃肠道障碍症状评分均明显下降,观察组低于对照组(P<0.05)。治疗后,两组患者GAS、MTI水平和治疗前相比均明显升高,且观察组高于对照组(P<0.05)。治疗后,观察组患者腹胀发生率为11.7%,低于对照组的30.0%(P<0.05)。治疗后,观察组患者腹胀程度明显低于对照组(P<0.05)。治疗后,两组患者抑郁状态评分均明显下降,观察组低于对照组(P<0.05)。两组不良反应发生率(6.7% 与5.0%)比较差异无统计学意义(P>0.05)。 结论:厚朴排气合剂联合经皮穴位电刺激可有效促进产后抑郁合并胃肠功能障碍患者胃肠功能恢复,缓解腹胀和抑郁情绪,而且不会明显增加不良反应发生率。
Abstract:
Objective:To explore the clinical effect of Magnolia exhaust mixture combined with percutaneous acupoint electrical stimulation on postpartum depression with gastrointestinal dysfunction.Methods:120 postpartum depression patients with gastrointestinal dysfunction were randomly divided into an observation group(n=60)and a control group(n=60).The control group was treated with percutaneous acupoint electrical stimulation,while the observation group was treated with Magnolia exhaust mixture combined with percutaneous acupoint electrical stimulation for 7 days.The recovery of gastrointestinal function,gastrointestinal disorder symptom score,gastrin(GAS),motilin(MTI),incidence and degree of abdominal distension,Hamilton Depression Scale score,and incidence of adverse reactions were compared between two groups of patients.Results:Compared with the control group,the observation group had shorter time of recovery of bowel sounds,first anal discharge,first bowel movement,and total hospital stay(P<0.05).After treatment,the scores of gastrointestinal disorders in both groups of patients significantly decreased,and the observation group was lower than the control group(P<0.05).After treatment,the levels of GAS and MTI in both groups of patients significantly increased compared to before treatment,and the observation group was higher than the control group(P<0.05).The incidence of abdominal distension in the observation group was 11.7%,lower than the 30.0% in the control group(P<0.05).The degree of abdominal distension in the observation group was significantly lower than that in the control group(P<0.05).The depression scores of both groups of patients significantly decreased,and the depression scores of the observation group were lower than those of the control group(P<0.05).The incidence of adverse reactions in the observation group was 6.7%,and there was no statistically significant difference compared to the control group's 5.0%(P>0.05).Conclusion:The combination of Magnolia exhaust mixture and percutaneous acupoint electrical stimulation has a significant therapeutic effect on postpartum depression combined with gastrointestinal dysfunction.It can effectively promote the recovery of gastrointestinal function,alleviate abdominal distension and depression in patients,and will not significantly increase the incidence of adverse reactions.

参考文献/References:

[1] ZHOU C,HU H,WANG C,et al.The effectiveness of mHealth interventions on postpartum depression:A systematic review and meta-analysis [J].Journal of Telemedicine and Telecare,2022,28(2):83-95.
[2] YANG S,YANG S,DUAN K,et al.The development and application of a prediction model for postpartum depression:Optimizing risk assessment and prevention in the clinic[J].Journal of Affectived Disorders,2022,296:434-442.
[3] 杨再,张玉丹,穆鑫,等.产后抑郁患者肠道微生物的特征[J].西安交通大学学报(医学版),2022,43(6):879-884.
[4] 胡燮军,王乐乐,甘建光.雌激素心理防御评分及胃肠功能与剖宫产产妇产后抑郁的相关性和危险因素分析[J].中国妇幼保健,2022,37(22):4250-4254.
[5] 王辉,杨保仲,郭祺,等.经皮穴位电刺激联合硬膜外分娩镇痛对产后抑郁症的影响[J].针刺研究,2021,46(3):231-234,253.
[6] 丁声双,黄伟华,段蓉蓉,等.经皮穴位电刺激对剖宫产产妇术后胃肠功能恢复影响的Meta分析[J].国际医药卫生导报,2022,28(21):3014-3019.
[7] 穆丽,高辉,赵麦良,等.经皮穴位电刺激对剖宫产术后胃肠道功能恢复的影响[J].中国针灸,2019,39(3):259-262.
[8] 中华医学会精神病学分会.中国精神障碍分类与诊断标准第三版(精神障碍分类)[J].中华精神科杂志,2001,34(3):184-188.
[9] 吴德辉.莫沙必利与马来酸曲美布汀联合用药方案治疗功能性消化不良的临床疗效评价[J].中国现代药物应用,2018,12(18):121-122.
[10] 穆丽,高辉,赵麦良,等.经皮穴位电刺激对剖宫产术后胃肠道功能恢复的影响[J].中国针灸,2019,39(3):259-262.
[11] SHI Y,LENG Y,LIU D,et al.Research advances in protective effects of ursolic acid and oleanolic acid against gastrointestinal diseases[J].The American Journal of Chinese Medicine,2021,49(2):413-435.
[12] 高怀军,余伟.腹腔镜结直肠癌根治术治疗结直肠癌临床疗效及对患者胃肠功能的影响[J].陕西医学杂志,2019,48(8):990-993.
[13] 刘建材,郑涵尹,潘卉,等.李传芬教授辨治功能性胃肠病伴焦虑抑郁经验[J].河北中医,2022,44(12):1954-1957.
[14] 马明霞.中药穴位贴敷配合耳穴埋豆对妇科患者手术后胃肠功能恢复效果研究[J].陕西中医,2018,39(8):1074-1076,1083.
[15] CAMACHO M,GREENLAND J C,CAROLINE H.The gastrointestinal dysfunction scale for parkinson's disease[J].Movement Disorders,2021,36(10):2358-2366.
[16] 王海芳,吕清巧,刘芳娥,等.新型针灸贴联合大黄贴治疗老年人功能性便秘的效果[J].中国医药导报,2020,17(31):142-145.
[17] 杨梦娟,柯攀,杨晓琴,等.大黄敷脐防治肿瘤患者化疗所致便秘的研究进展[J].西部中医药,2019,32(8):154-157.
[18] 张鹏,李娜,郑继会,等.厚朴排气合剂联合针刺穴位对胸腰椎术后胃肠功能恢复的影响[J].吉林中医药,2022,42(6):729-732.
[19] 张淑洁,钟凌云.厚朴化学成分及其现代药理研究进展[J].中药材,2013,36(5):838-843.
[20] 张正选,李鲜.枳实改善功能性消化不良大鼠胃动力障碍的机制研究[J].陕西中医,2018,39(8):998-1000.
[21] 李宁,何华东,谢玺,等.厚朴排气合剂对腹腔镜下腹膜外前列腺癌根治术后胃肠功能快速康复的影响[J].实用临床医药杂志,2018,22(17):43-45,49.
[22] 赵嵩博,王满才,韩永东,等.厚朴排气合剂治疗术后胃肠动力障碍的研究进展[J].现代中西医结合杂志,2023,32(12):1749-1752.
[23] 张蕾,吕健,谢雁鸣.厚朴排气合剂治疗术后早期肠麻痹有效性和安全性的Meta分析[J].中国药物警戒,2023,20(7):799-806.
[24] 郑淑敏,张红,孙春亭,等.超声低中频电导治疗仪治疗与厚朴排气合剂对剖宫产术后胃肠道功能的影响[J].世界中医药,2021,16(16):2463-2467.
[25] 张晓旭,王晓超,陈云.厚朴排气合剂对瘢痕子宫再次剖宫产术后使用镇痛泵者胃肠功能恢复的影响[J].河北中医,2018,40(1):58-51.
[26] 张成盈,姜璐,王永森,等.基于网络药理学和分子对接探讨厚朴排气合剂治疗慢性便秘潜在作用机制[J].现代药物与临床,2023,38(9):2146-2154.
[27] 辛阿媛,辛小玲,高兰.厚朴排气合剂对妇科手术患者术后胃肠功能恢复的影响[J].临床医学工程,2023,30(7):939-940.
[28] 赵嵩博,王满才,韩永东,等.厚朴排气合剂治疗术后胃肠动力障碍的研究进展[J].现代中西医结合杂志,2023,32(12):1749-1752.

相似文献/References:

[1]郑 舒,何 津,单延红.逍遥散联合维生素D对产后抑郁大鼠行为学及脑组织形态学的影响[J].陕西中医,2021,(10):1333.[doi:DOI:10.3969/j.issn.1000-7369.2020.10.003]
　ZHENG Shu,HE Jin,SHAN Yanhong.Effect of Xiaoyao powder combined with vitamin D on behavior and brain histomorphology in rats with postpartum depression[J].,2021,(1):1333.[doi:DOI:10.3969/j.issn.1000-7369.2020.10.003]
[2]徐 敏,王建伟.大黄脐贴治疗脓毒症胃肠功能障碍临床研究[J].陕西中医,2022,(11):1531.[doi:DOI:10.3969/j.issn.1000-7369.2022.11.009]
　XU Min,WANG Jianwei.Clinical observation of rhubarb umbilical patch in the treatment of gastrointestinal dysfunction in sepsis[J].,2022,(1):1531.[doi:DOI:10.3969/j.issn.1000-7369.2022.11.009]

备注/Memo

备注/Memo:
基金项目:河北省医学科学研究课题(20210582); 河北省秦皇岛市科学技术研究与发展计划项目(201902A107)
更新日期/Last Update: 2024-01-09