[1]吴智龙,殷继超,胡兴律,等.强直性脊柱炎发病与二十四节气相关性研究[J].陕西中医,2024,(1):75-79.[doi:DOI:10.3969/j.issn.1000-7369.2024.01.017]
 WU Zhilong,YIN Jichao,HU Xinglv,et al.A study on the correlation between the onset of ankylosing spondylitis and the twenty-fourth festival season[J].,2024,(1):75-79.[doi:DOI:10.3969/j.issn.1000-7369.2024.01.017]
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强直性脊柱炎发病与二十四节气相关性研究
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2024年1期
页码:
75-79
栏目:
临床研究
出版日期:
2024-01-05

文章信息/Info

Title:
A study on the correlation between the onset of ankylosing spondylitis and the twenty-fourth festival season
作者:
吴智龙1殷继超2胡兴律3刘英纯4刘诗若3李 霖1赵 宇1
(1.陕西中医药大学,陕西 咸阳 712046; 2.西安市卫生学校,陕西 西安 710054; 3.西安市中医医院,陕西 西安 710021; 4.西安市第五医院,陕西 西安 710082)
Author(s):
WU ZhilongYIN JichaoHU XinglvLIU YingchunLIU ShiruoLI LinZHAO Yu
(Shaanxi University of Chinese Medicine,Xianyang 712046,China)
关键词:
强直性脊柱炎 圆形统计分析 二十四节气 气候 因时制宜 发病季节
Keywords:
Ankylosing spondylitis Circular statistical analysis Twenty-four solar terms Climate Right crop for right time Season of onset
分类号:
R 593.23
DOI:
DOI:10.3969/j.issn.1000-7369.2024.01.017
文献标志码:
A
摘要:
目的:分析陕西地区近19年强直性脊柱炎发病与二十四节气间的相关性,从时间医学角度为因时制宜理论提供临床依据。方法:采用回顾性研究方法对西安市第五医院2002年2月4日至2020年2月3日收治的12645例强直性脊柱炎住院患者的病历资料进行分析,应用圆形统计分析确定其发病高峰节气及相对高峰期。结果:2002—2020年陕西地区强直性脊柱炎患者的在发病节气上具有集中趋势(Z=47.73,P<0.05),大暑(8月5日)是发病的高峰节气,相对高峰期为春分到大雪(3月21日至12月20日)。结论:强直性脊柱炎虽不是季节性流行病,但是其发病与气候、环境及二十四节气的变化有一定的影响,陕西地区强直性脊柱炎的发病节气具有一定的集中趋势,大暑前后是发病高峰期,提示应注意该节气期间疾病的预防和早期治疗。
Abstract:
Objective:To analyze the correlation between the incidence of ankylosing spondylitis and the twenty-four seasons in Shaanxi region in the past 19 years,and to provide a clinical basis for the theory of seasonal adaptation from the perspective of chronomedicine.Methods:The medical records of 12645 ankylosing spondylitis inpatients admitted to the Fifth Hospital of Xi'an City from February 4,2002 to February 3,2020 were analyzed using retrospective research methods,and circular statistical analysis was applied to determine the peak seasons of incidence and the relative peak periods.Results:From 2002 to 2020,patients with ankylosing spondylitis in Shaanxi had a tendency to concentrate on the onset of the disease(Z=47.73,P<0.05),with the peak season of onset being the Great Summer(August 5)and the relative peak period being from the vernal equinox to the Great Snow(March 21-December 20),which was the most common time for the onset of the disease.Conclusion:Although ankylosing spondylitis is not a seasonal epidemic,its onset has a certain influence on the climate,environment and the changes of the 24 solar terms.The onset of ankylosing spondylitis in Shaanxi has a certain tendency to be centralized in terms of solar terms,and the peak period of the onset of the disease is before and after the Great Summer,suggesting that attention should be paid to the prevention of the disease and the early treatment of the disease during the period of the solar term.

参考文献/References:

[1] 北京中西医结合学会风湿病专业委员会.强直性脊柱炎长期管理专家共识(2021年)[J].中国中西医结合杂志,2021,41(12):1426-1434.
[2] KLAVDIANOU K,TSIAMI S,BARALIAKOS X.New developments in ankylosing spondylitis-status in 2021[J].Rheumatology(Oxford),2021,60(S6):29-37.
[3] 杜琳,高延征.强直性脊柱炎诊断及治疗新进展[J].中华实用诊断与治疗杂志,2019,33(7):629-631.
[4] 郭乃亮.补肾强督治尪汤加减治疗肾虚督寒型强直性脊柱炎疗效及对患者炎症因子的影响[J].陕西中医,2019,40(10):1394-1396.
[5] 杨超,李鹏飞,张路霞.大气污染及气候因素对肾脏疾病的影响及其生物学机制研究进展[J].解放军医学杂志,2022,47(1):72-77.
[6] ZHANG T,QIN W,NIE T,et al.Effects of meteorological factors on the incidence of varicella in Lu'an,Eastern China,2015-2020[J].Environ Sci Pollut Res Int,2023,30(4):10052-10062.
[7] 刘家豪,黄凤.中医时间医学研究综述[J].中华中医药杂志,2022,37(10):5880-5882.
[8] 刘天,黄继贵,姚梦雷,等.发病季节性分析的7种常用方法比较[J].预防医学,2019,31(2):187-190.
[9] 朱岁松.圆形分布时间与日期资料的角度转换[J].数理医药学杂志,2009,22(2):193-194.
[10] 牛敏,杨西超,闫美茜,等.强直性脊柱炎患者肥胖与炎性指标、疾病严重程度指标和心血管疾患危险因素指标相关性分析[J].陕西医学杂志,2021,50(11):1383-1386.
[11] 王典,于静.强直性脊柱炎的中医研究进展[J].国医论坛,2022,37(1):76-78.
[12] 周淑蓓,郑福增,展俊平.国医大师朱良春运用培补肾阳汤治疗强直性脊柱炎临床经验[J].时珍国医国药,2020,31(4):966-967.
[13] 李雪枫,袁普卫,康武林,等.李堪印教授从筋论治强直性脊柱炎的经验[J].中医正骨,2021,33(11):53-55.
[14] 杜燕,茆春阳,周波,等.浅论强直性脊柱炎归于肝[J].陕西中医,2020,41(4):515-517.
[15] 张轩,刘忠第,贺娟.《黄帝内经》运气思想在疾病发生与药物治疗的应用研究[J].中华中医药杂志,2021,36(6):3121-3124.
[16] CHALLIER B,URLACHER F,VANCON G,et al.Is quality of life affected by season and weather conditions in ankylosing spondylitis?[J].Clin Exp Rheumatol,2001,19(3):277-281.
[17] YAZMALAR L,EDIZ L,ALPAYCI M,et al.Seasonal disease activity and serum vitamin D levels in rheumatoid arthritis,ankylosing spondylitis and osteoarthritis[J].Afr Health Sci,2013,13(1):47-55.
[18] ENGINAR A U,KACAR C.Neutrophil-lymphocyte and platelet-lymphocyte rate and their seasonal differences in ankylosing spondylitis and rheumatoid arthritis patients using anti-TNF medication[J].Bratisl Lek Listy,2019,120(8):586-592.
[19] XIN L,LIU J,ZHU Y,et al.Exposure-lag-response associations between weather conditions and ankylosing spondylitis:A time series study[J].BMC Musculoskelet Disord,2021,22(1):641.
[20] LANDLER L,RUXTON G D,MALKEMPER E P.The Hermans-Rasson test as a powerful alternative to the Rayleigh test for circular statistics in biology[J].BMC Ecol,2019,19(1):30.
[21] LANDLER L,RUXTON G D,MALKEMPER E P.The multivariate analysis of variance as a powerful approach for circular data[J].Mov Ecol,2022,10(1):21.
[22] 黄玉燕.2020—2021年度《黄帝内经》研究进展[J].中国中医基础医学杂志,2022,28(12):1909-1914.
[23] 马桂琴.经方关于风湿病“位”、“势”、“态”探讨[J].中国中医基础医学杂志,2011,17(8):841-843.
[24] 马桂琴.兼论五运六气、风湿病与经方辨治[J].中国中医基础医学杂志,2012,18(6):585-587.
[25] 马桂琴,沙正华.五运六气与类风湿关节炎发病相关性研究[J].中国中医基础医学杂志,2018,24(6):778-781.
[26] 李正富,吴德鸿,王新昌,等.五运六气禀赋与类风湿关节炎发病的相关性研究[J].浙江中医药大学学报,2015,39(7):505-507.
[27] 汪元,刘健.从中医整体观谈中医痹证的临床与科研[J].中国中医基础医学杂志,2013,19(9):1007-1008.
[28] 韩善夯.强直性脊柱炎中医证候分型与炎症相关性分析[J].中华中医药杂志,2019,34(12):5957-5959.
[29] 张金山,张方园,万磊,等.强直性脊柱炎的磁共振成像炎症分期与中医证型和临床特征关系[J].安徽中医药大学学报,2017,36(6):11-13.
[30] 隋斌,张建军.二十四节气的内涵、价值及传承发展[J].中国农史,2020,39(6):111-117.
[31] 姜青松,韩彦君,罗建,等.二十四节气与中医学[J].中华中医药杂志,2019,34(4):1653-1656.
[32] ZHANG G J,GAO R,FU J K,et al.Climatic conditions and the onset of primary spontaneous pneumothorax:An investigation of the influence of solar terms[J].Med Princ Pract,2012,21(4):345-349.
[33] 郝宇,贺娟.北京地区10种常见疾病的发病节气规律分析[J].中华中医药杂志,2017,32(3):1001-1004.
[34] 成芸,冯志海.浅析因时制宜在强直性脊柱炎治疗的应用[J].风湿病与关节炎,2019,8(9):60-61.
[35] 孟旭,赵吉平,程璐,等.中医时间节律在针灸临床中的应用[J].中医杂志,2020,61(4):311-314.
[36] 胡剑威,马丽,董利平.子午流注针法联合针刀疗法治疗强直性脊柱炎40例[J].风湿病与关节炎,2014,3(6):8-11.
[37] 李苏茜,张宏,刘宇,等.子午流注理论应用于膝骨关节炎中医治疗的研究进展[J].风湿病与关节炎,2019,8(8):73-75.

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备注/Memo

备注/Memo:
基金项目:陕西省重点研发计划项目(2023-YBSF-158,2022SF-173,2021SF-372); 西安市科技计划项目[20YXYJ0003(6)]
更新日期/Last Update: 2024-01-09