[1]张子洁,刘海健,彭 生.血必净对心肌细胞缺血再灌注损伤保护作用研究进展[J].陕西中医,2024,(1):139-142.[doi:DOI:10.3969/j.issn.1000-7369.2024.01.033]
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血必净对心肌细胞缺血再灌注损伤保护作用研究进展
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2024年1期
页码:
139-142
栏目:
综 述
出版日期:
2024-01-05

文章信息/Info

作者:
张子洁1; 2; 刘海健2; 彭 生1; 3
(1.上海中医药大学附属龙华临床医学院,上海 200030; 2.上海健康医学院附属周浦医院麻醉科,上海 201318; 3.上海中医药大学附属龙华医院麻醉科,上海 200030)
关键词:
心肌缺血再灌注损伤;  血必净;  抗氧化;  炎症反应;  微循环
分类号:
R 542.2
DOI:
DOI:10.3969/j.issn.1000-7369.2024.01.033
文献标志码:
A
摘要:
尽管临床实践中严重心血管不良事件的发生率较以往明显减少,但是心肌细胞缺血再灌注损伤后遗症仍然是临床难题和研究热点。引起心肌细胞缺血再灌注损伤的机制较多,目前已知的机制包括炎性细胞浸润、氧化应激损伤、血管内皮细胞缺氧坏死以及细胞凋亡等。作为在临床上已经广泛使用,且具有代表性中成药物,血必净注射液已经被证实可通过多靶点作用治疗心肌细胞缺血再灌注损伤,也一直是临床药物治疗学的研究热点。现拟结合近年来国内外研究报道,对血必净在心肌细胞缺血再灌注损伤中的研究进展情况进行综述。

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备注/Memo

备注/Memo:
基金项目:上海市浦东新区卫生健康委员会科研项目(PW2020A-12)
更新日期/Last Update: 2024-01-09