[1]苏玉凤,吕凤娟,宣翔虎,等.天竹定眩汤联合“治神调髓”针刺法治疗卒中后眩晕疗效研究[J].陕西中医,2024,(3):403-406.[doi:DOI:10.3969/j.issn.1000-7369.2024.03.027]
　SU Yufeng,LYU Fengjuan,XUAN Xianghu,et al.Study on curative effect of Tianzhu Dingxuan decoction combined with Zhishen Tiaosui acupuncture on vertigo after stroke[J].,2024,(3):403-406.[doi:DOI:10.3969/j.issn.1000-7369.2024.03.027]
点击复制

天竹定眩汤联合“治神调髓”针刺法治疗卒中后眩晕疗效研究
分享到：

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2024年3期
页码:
403-406
栏目:
针灸经络
出版日期:
2024-03-05

文章信息/Info

Title:
Study on curative effect of Tianzhu Dingxuan decoction combined with Zhishen Tiaosui acupuncture on vertigo after stroke
作者:
苏玉凤1; 吕凤娟1; 宣翔虎1; 智 勇2
(1.安徽医科大学附属滁州医院,安徽 滁州 239000; 2.新疆医科大学中医学院,新疆 乌鲁木齐 830017)
Author(s):
SU Yufeng; LYU Fengjuan; XUAN Xianghu; ZHI Yong
(Chuzhou Hospital of Anhui Medical University,Chuzhou 239000,China)
关键词:
卒中后眩晕;  天竹定眩汤;  “治神调髓”针刺;  神经功能;  血液流变;  脑动脉血流速度
Keywords:
Post stroke vertigo;  Tianzhu Dingxuan decoction;  Zhishen Tiaosui acupuncture;  Neural function;  Hemorheology;  Cerebral artery flow velocity
分类号:
R 255.2
DOI:
DOI:10.3969/j.issn.1000-7369.2024.03.027
文献标志码:
A
摘要:
目的:探讨天竹定眩汤联合“治神调髓”针刺法治疗卒中后眩晕的临床疗效。方法:将收治的84例卒中后眩晕患者进行前瞻性研究,按随机数字表法分为观察组、对照组,各42例。对照组给予“治神调髓”针刺法治疗,观察组在对照组基础上给予天竹定眩汤加减治疗。观察两组治疗前后临床疗效、中医证候评分,通过彩超检测脑动脉平均血流速度、相关量表评分、血清神经功能指标、血液流变学指标及安全性评价。结果:治疗后,观察组总有效率为90.48%,高于对照组71.43%,差异有统计学意义(P<0.05)。治疗后,两组中医证候评分、血清胶质纤维酸性蛋白、血液流变学指标、眩晕障碍量表评分均较治疗前降低,且观察组低于对照组,差异有统计学意义(均P<0.05)。治疗后,两组大脑动脉平均血流速度、血清脑源性神经营养因子、血清神经生长因子水平、Berg平衡表评分均较治疗前升高,且观察组高于对照组,差异有统计学意义(均P<0.05)。结论:天竹定眩汤联合“治神调髓”针刺法治疗卒中后眩晕临床疗效较好。
Abstract:
Objective:To investigate clinical effect of Tianzhu Dingxuan decoction combined with Zhishen Tiaosui acupuncture on patients with vertigo after stroke.Methods:84 patients with vertigo after stroke were prospectively studied,divided into observation group and control group by random number table method,42 cases in each group.The control group were treated with Zhishen Tiaosui acupuncture,and the observation group were treated with Tianzhu Dingxuan decoction on the basis of the control group.To observe clinical efficacy,TCM syndrome score,average cerebral artery blood flow velocity,scores of related scales,serum neurological function indexes,hemorheology indexes and safety evaluation.Results:After treatment,the observation group total effective rate was 90.48% higher than that in the control group 71.43%,difference statistically significant(P<0.05).After treatment,TCM syndrome score,serum glial fibrillary acidic protein,whole blood low tangential viscosity,whole blood high tangential viscosity,plasma viscosity level and vertigo disorder scale score in the two groups were lower than before treatment and the above indicators in the observertion group were lower than those in the control group,difference statistically significant(all P<0.05).After treatment,average cerebral artery blood flow velocity,serum brain-derived neurotrophic factor,serum nerve growth factor and Berg balance score in the two groups were higher than before and the above indicators in the observertion group were lower than those in the control group,difference statistically significant(all P<0.05).Conclusion:Tianzhu Dingxuan decoction combined with Zhishen Tiaosui acupuncture has significant clinical effect on patients with vertigo after stroke.

参考文献/References:

[1] 高福芬.老年人眩晕综合征的病因分析[J].陕西医学杂志,2010,39(4):473-474,477.
[2] 徐霞,卜行宽.眩晕的流行病学研究[J].临床耳鼻咽喉科杂志,2006,20(7):334-336.
[3] 周丽萍.眩晕的流行病学调查研究[J].中国实用神经疾病杂志,2010,13(18):31-32.
[4] 陈佳鑫,席强,李岩琪.针灸干预后循环缺血性眩晕研究进展[J].光明中医,2023,38(2):387-391.
[5] 陶丽,骞健.全脑血管造影术患者围手术期的护理[J].陕西医学杂志,2012,41(8):1099-1101.
[6] 李鑫,张智龙,许可.早期针刺治疗对后循环缺血性眩晕痰浊上蒙证患者的疗效观察[J].辽宁中医杂志,2023,50(2):166-169.
[7] 李智俐,屈绮文,林漫婷.清眩方结合“小醒脑开窍”针刺法治疗后循环缺血性眩晕(痰瘀互结证)的临床观察[J].中国中医急症,2023,32(1):130-132.
[8] 蒋霞.针灸结合穴位贴敷在脑动脉供血不足型眩晕患者中的应用[J].陕西中医,2022,43(7):950-953.
[9] 朱毅,陈建秋,李勇,等.行气通脉方治疗痰瘀阻络型后循环缺血性眩晕的临床疗效[J].世界中西医结合杂志,2021,16(5):912-916,922.
[10] 惠荣,唐远山,许磊,等.定眩饮治疗后循环缺血性眩晕临床研究[J].陕西中医,2022,43(2):204-206.
[11] 王武庆,付蓉,毕国荣,等.血管源性头晕/眩晕诊疗中国专家共识[J].中国神经免疫学和神经病学杂志,2020,27(4):253-260.
[12] 吴勉华,王新月.中医内科学[M].北京:中国中医药出版社,2012:276.
[13] 国家中医药管理局.中药新药临床研究指导原则[M].北京:中国医药科技出版社,2002:99.
[14] 国家中医药管理局.中医病证诊断疗效标准[M].南京:南京大学出版社,1994:139-142.
[15] 刘化飞,唐松林.奥拉西坦联合倍他司汀对卒中后眩晕患者炎症因子及神经功能的影响[J].脑与神经疾病杂志,2023,31(1):48-52.
[16] IMAI T,INOHARA H.Benign paroxysmal positional vertigo[J].Auris Nasus Larynx,2022,49(5):737-747.
[17] 陈光,付淼.急性缺血性脑卒中患者脑血管储备功能与其急诊治疗结局相关性分析[J].陕西医学杂志,2023,52(1):53-56.
[18] 全毅恒,上官晨虹,陈琛.天麻中酚类成分对心脑血管疾病的药理作用研究进展[J].中草药,2022,53(14):4582-4592.
[19] 吴国真,贾传青,王晓,等.天麻多糖的提取、纯化及药理活性研究进展[J].中华中医药学刊,2022,40(7):135-139.
[20] 吴嘉朔,常晓燕,李壮壮,等.泽泻汤降脂及抗炎作用分子机制研究进展[J].中国实验方剂学杂志,2021,27(2):224-232.
[21] 王依明,王秋红.半夏的化学成分、药理作用及毒性研究进展[J].中国药房,2020,31(21):2676-2682.
[22] 俞静静,苏洁,吕圭源.陈皮抗心脑血管疾病相关药理研究进展[J].中草药,2016,47(17):3127-3132.
[23] 何邵波,黄泽智,李丽钱.川陈皮素对哮喘大鼠内质网应激信号通路及核苷酸结合寡聚化结构域样受体蛋白3炎症小体活化的影响[J].中国临床药理学杂志,2023,39(4):528-532.
[24] 李茎,郑鹏,黎攀,等.广陈皮药理作用与临床应用研究进展[J].吉林中医药,2022,42(9):1092-1095.
[25] 叶青,刘东升,王兰霞,等.茯苓化学成分、药理作用及质量控制研究进展[J].中医药信息,2023,40(2):75-79.

备注/Memo

备注/Memo:
基金项目:国家自然科学基金资助项目(82060894)
更新日期/Last Update: 2024-03-08