[1]齐 涛,张闻东,李佩芳,等.通督调神针法治疗阴虚动风型脑梗死偏瘫疗效及对患者血清Hcy、CRP水平的影响[J].陕西中医,2024,(5):696-699.[doi:DOI:10.3969/j.issn.1000-7369.2024.05.028]
　QI Tao,ZHANG Wendong,LI Peifang,et al.Curative effect of Tongdu Tiaoshen acupuncture and its influences on serum Hcy and CRP in patients with cerebral infarction hemiplegia of yin-deficiency wind blowing type[J].,2024,(5):696-699.[doi:DOI:10.3969/j.issn.1000-7369.2024.05.028]
点击复制

通督调神针法治疗阴虚动风型脑梗死偏瘫疗效及对患者血清Hcy、CRP水平的影响
分享到：

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2024年5期
页码:
696-699
栏目:
针灸经络
出版日期:
2024-05-05

文章信息/Info

Title:
Curative effect of Tongdu Tiaoshen acupuncture and its influences on serum Hcy and CRP in patients with cerebral infarction hemiplegia of yin-deficiency wind blowing type
作者:
齐 涛; 张闻东; 李佩芳; 刘 辉
(安徽中医药大学第二附属医院,安徽 合肥 230001)
Author(s):
QI Tao; ZHANG Wendong; LI Peifang; LIU Hui
(The Second Affiliated Hospital of Anhui University of Chinese Medicine,Hefei 230001,China)
关键词:
脑梗死偏瘫;  通督调神针法;  阴虚动风型;  血清同型半胱氨酸;  C反应蛋白;  运动功能
Keywords:
Cerebral infarction hemiplegia;  Tongdu Tiaoshen acupuncture;  Yin-deficiency wind blowing type;  Serum homocysteine;  C-reactive protein;  Motor function
分类号:
R 743.3
DOI:
DOI:10.3969/j.issn.1000-7369.2024.05.028
文献标志码:
A
摘要:
目的:探讨通督调神针法治疗阴虚动风型脑梗死偏瘫患者疗效及对患者血清同型半胱氨酸(Hcy)、C反应蛋白(CRP)水平的影响。方法:选取脑梗死偏瘫患者76例,1:1随机分为观察组(西医治疗+通督调神针法)与对照组(常规西医治疗)各38例。持续治疗1个月后,评估两组临床疗效,比较两组治疗前后中医证候积分、血清炎症因子(Hcy、CRP)水平、运动功能[Fugl-Meyer评定量表(FMA)]、平衡功能[Berg平衡量表(BBS)]和移动功能[功能性步态评价表(FGA)]变化情况,并记录两组不良事件发生率。结果:观察组总有效率更高(P<0.05); 观察组治疗后中医证候积分降低程度比对照组更明显(P<0.05)。观察组治疗后FMA、FGA和BBS评分升高水平均比对照组更明显(P<0.05),观察组治疗后Hcy、CRP水平下降程度均比对照组更明显(P<0.05)。治疗期间两组均无不良事件发生。结论:阴虚动风型脑梗死偏瘫患者应用通督调神针法联合常规西医治疗具有较好的增益效果,可有效提高临床疗效,缓解患者临床症状,提高运动、平衡和移动能力,降低炎症反应。
Abstract:
Objective:To explore the curative effect of Tongdu Tiaoshen acupuncture and its influences on serum homocysteine(Hcy)and C-reactive protein(CRP)in patients with cerebral infarction hemiplegia of yin-deficiency wind blowing type.Methods:A total of 76 patients were randomly divided into the observation group(western medicine treatment + Tongdu Tiaoshen acupuncture)and the control group(conventional western medicine treatment),38 cases in each group.All patients were treated for 1 month.The changes in scores of TCM syndromes,levels of serum inflammatory factors(Hcy,CRP),motor function [Fugl-Meyer Assessment Scale(FMA)],balance function [Berg Balance Scale(BBS)] and mobility function [Functional Gait Assessment(FGA)] before and after treatment were compared between the two groups.The incidence of adverse events in both groups was recorded.Results:The total response rate of observation group was significantly higher than that of control group(94.74% vs 78.95%,P<0.05).After treatment,scores of TCM syndromes in both groups were decreased,which were lower in observation group than control group(P<0.05).After treatment,FMA,FGA and BBS scores in both groups were increased,which were higher in observation group than control group(P<0.05).After treatment,levels of Hcy,CRP in both groups were decreased,which were lower in observation group than control group(P<0.05).There were no adverse events in either group during treatment.Conclusion:Tongdu Tiaoshen acupuncture combined with conventional western medicine has a good enhancement effect in the treatment of patients with cerebral infarction hemiplegia of Yin deficiency and wind movement,which can effectively improve the clinical efficacy,relieve the clinical symptoms of patients,improve the ability of movement,balance and mobility,and reduce inflammatory response.

参考文献/References:

[1] 包蕾.阿加曲班联合阿司匹林治疗急性脑梗死疗效及对患者血管内皮功能的影响[J].陕西医学杂志,2021,50(5):603-605,625.
[2] WEI J,ZHU X,XIA L,et al.ntermittent pneumatic compression combined with rehabilitation training improves motor function deficits in patients with acute cerebral infarction[J].Acta Neurol Belg,2021,121(6):1561-1566.
[3] 林少英,郑一帆,叶莉,等.神经肌肉关节促进法对脑梗死偏瘫患者下肢肌张力的影响[J].新医学,2022,53(9):660-664.
[4] 唐艺丹,姚智.针灸联合中医康复治疗脑卒中后躯干控制障碍研究进展[J].陕西中医,2023,44(7):987-989.
[5] 鲍勇,项尚,朱莎,等.天麻钩藤饮联合抗血小板治疗对阴虚风动型缺血性中风患者疗效、血清Hcy与CRP影响[J].辽宁中医药大学学报,2021,23(8):175-178.
[6] 江丽,孙蔚,祝青青,等.镇肝熄风汤联合针刺治疗老年急性脑梗死(阴虚风动证)的临床观察[J].中国中医急症,2021,30(9):1616-1619.
[7] 赵亚楠,吴文忠,刘成勇,等.“通督调神”针法治疗失眠的理论探微[J].针灸临床杂志,2019,35(6):1-4.
[8] 中华医学会神经病学分会,中华医学会神经病学分会脑血管病学组.中国急性缺血性脑卒中诊治指南2018[J].中华神经科杂志,2018,51(9):666-682.
[9] 中华人民共和国卫生部.中国新药临床研究指导原则[M].北京:中国医药科技出报社,2002:101.
[10] 张磊,刘建民.美国国立卫生研究院卒中量表[J].中华神经外科杂志,2014,30(1):79.
[11] 茂斌.偏瘫的现代评价与治疗[M].北京:华夏出版社,1990:226-231.
[12] 国家中医药管理局.中医病证诊断疗效标准[M].南京:南京大学出版社,1994:39.
[13] 黄蓓.《证候类中药新药临床研究技术指导原则》发布[J].中医药管理杂志,2018,26(21):1-2.
[14] 陈瑞全,吴建贤,沈显山.中文版Fugl-Meyer运动功能评定量表的最小临床意义变化值的研究[J].安徽医科大学学报,2015,50(4):519-522.
[15] 杨雅琴,周亚楠,王拥军,等.功能性步态评价在帕金森病患者中的效度[J].中国康复理论与实践,2018,24(11):95-98.
[16] JEON Y J,KIM G M.Comparison of the berg balance scale and fullerton advanced balance scale to predict falls in community-dwelling adults[J].J Phys Ther Sci,2017,29(2):232-234.
[17] 黄英媛,宋振华,徐焕杰,等.补阳还五汤联合梅花针叩刺治疗脑梗死偏瘫疗效研究[J].陕西中医,2020,41(6):815-818.
[18] 马志辉,杨艳君,刘兢,等.不同针刺方法治疗阴虚风动型脑梗死后运动性失语症的平行对照研究[J].四川中医,2019,37(5):176-178.
[19] 赵晓君,赵桂娥,刘红梅,等.通督调神针法联合康复训练治疗缺血性脑卒中患者吞咽障碍临床疗效观察[J].四川中医,2022,40(1):190-194.
[20] 牛玉莲,支颍川,李娟,等.通督调神针刺结合重复经颅磁刺激对脑梗死患者康复治疗的效果观察[J].世界中医药,2022,17(9):1322-1325,1330.
[21] 幸冰峰,周歆,邓先琴.通督调神针法联合吞咽训练对缺血性脑卒中吞咽障碍患者的疗效及对脑血流和血清神经营养因子的影响[J].针刺研究,2019,44(7):506-511.
[22] 郭新年,口锁堂.针刺法治疗急性脑梗死对患者脑血管储备和神经元炎症水平的影响[J].解放军预防医学杂志,2019,37(8):63-64.
[23] 刘启,梁丹丹,许伶,等.针刺百会穴、风府穴对脑缺血损伤大鼠神经功能及NGF、BDNF表达的影响[J].河南中医,2018,38(8):1168-1171.
[24] 吴国访,张丽,张淑沛,等.LPA、Hcy、MCP-1与缺血性脑卒中患者神经损伤和侧支循环的关系[J].分子诊断与治疗杂志,2021,13(2):199-202.
[25] 夏瑜,康艳飞,曹敬然,等.RDW联合血清CRP、PCT、sTLT-1与急性脑梗死患者脑梗死体积、神经功能受损程度和预后的关系研究[J].现代生物医学进展,2022,22(12):2356-2360.

备注/Memo

备注/Memo:
基金项目:安徽省卫生和计划生育委员会-中医药发展课题[(2018)23号]
更新日期/Last Update: 2024-05-09