[1]刘国强,郭琳娟,贺阿利,等.放血联合电针治疗突发性耳聋临床研究[J].陕西中医,2024,(7):980-984.[doi:DOI:10.3969/j.issn.1000-7369.2024.07.027]
　LIU Guoqiang,GUO Linjuan,HE Ali,et al.Clinical study on treatment of sudden hearing loss with combination of bloodletting and electroacupuncture[J].,2024,(7):980-984.[doi:DOI:10.3969/j.issn.1000-7369.2024.07.027]
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放血联合电针治疗突发性耳聋临床研究
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2024年7期
页码:
980-984
栏目:
针灸经络
出版日期:
2024-07-05

文章信息/Info

Title:
Clinical study on treatment of sudden hearing loss with combination of bloodletting and electroacupuncture
作者:
刘国强1; 郭琳娟1; 贺阿利1; 陆 鹤2; 赵卫锋3; 高 丽1; 王乾娜1; 王珍珍1; 潘龙康1; 张润子1; 王晓霞1
(1.陕西省中医医院,陕西 西安 710003; 2.西安市中心医院,陕西 西安 710004; 3.西安市中医医院,陕西 西安 710021)
Author(s):
LIU Guoqiang; GUO Linjuan; HE Ali; LU He; ZHAO Weifeng; GAO Li; WANG Qianna; WANG Zhenzhen; PAN Longkang; ZHANG Runzi; WANG Xiaoxia
(Shaanxi Provincial Hospital of Traditional Chinese Medicine,Xi'an 710003,China)
关键词:
突发性耳聋;  放血;  电针;  纯音听阈值;  中医证候积分;  内皮素-1;  一氧化氮
Keywords:
Suddenhearing loss;  Bloodletting;  Electroacupuncture;  Pure tone hearing threshold;  TCM syndrome scores;  Endothelin-1;  Nitric oxide
分类号:
R 764.43
DOI:
DOI:10.3969/j.issn.1000-7369.2024.07.027
文献标志码:
A
摘要:
目的:明确放血联合电针治疗急性期实证突发性耳聋(SHL)临床疗效,从血管内皮功能方面[血清内皮素-1(ET-1)、血清一氧化氮(NO)]探讨其作用机制。方法:将80例急性期实证SHL患者按随机数字表格法分成电针组40例、电针加放血组40例。电针组给予口服常规药物及针刺、电针治疗,电针加放血组在电针组治疗基础上给予翳风、背俞穴放血治疗。4个疗程后比较分析两组患者疗效、中医证候积分、纯音听阈值、血清ET-1、血清NO。结果:治疗后,电针加放血组总有效率为89.7%,高于电针组总有效率64.1%(P<0.05)。两组纯音听阈值、中医证候积分均降低,电针加放血组低于电针组(P<0.05)。两组血清ET-1水平均降低,血清NO水平均升高,电针加放血组血清ET-1水平低于电针组(P<0.05),血清NO水平高于电针组(P<0.05),整个研究期间无不良反应出现。结论:翳风、背俞穴放血联合电针治疗急性期实证SHL疗效较好,可能通过改善血管内皮功能起效,不良反应少。
Abstract:
Objective:To clarify clinical efficacy of bloodletting therapy combined with electroacupuncture in treatment of acute phase of empirical sudden hearing loss,and to explore vascular endothelial function aspects endothelin-1(ET-1),serum NO in terms of its mechanism of action.Methods:Using random number table method,80 patients with acute phase of empirical sudden hearing loss were divided into 40 cases each in the electroacupuncture group and the electroacupuncture plus bloodletting group.The electroacupuncture group were given oral conventional drugs acupuncture and electroacupuncture treatment,while the electroacupuncture plus bloodletting group were given bloodletting treatment at Yifeng and Beishu points on the basis of electroacupuncture treatment.After four courses of treatment,the clinical efficacy,pure tone hearing threshold,TCM syndrome scores,serum ET-1,and serum NO of the two groups of patients were compared and analyzed.Results:After the treatment,total effective rate of the electroacupuncture plus bloodletting group was 89.7% higher than that in the electroacupuncture group of 64.1%(P<0.05).The pure tone hearing threshold and TCM symptom score of the electroacupuncture group and the electroacupuncture plus bloodletting group decreased,while the electroacupuncture plus bloodletting group were lower than the electroacupuncture group(P<0.05).The serum ET-1 levels decreased and the serum NO levels increased in both the electroacupuncture group and the electroacupuncture plus bloodletting group(P<0.05).The serum ET-1 level of the electroacupuncture plus bloodletting group were lower than that in the electroacupuncture group,and the serum NO level of the electroacupuncture plus bloodletting group were higher than that in the electroacupuncture group(P<0.05).There were no adverse reactions during the entire study period.Conclusion:Bloodletting at Yifeng and Beishu points combined with electroacupuncture treatment has better therapeutic effect on acute phase empirical sudden hearing loss,which may take effect by improving vascular endothelial function with fewer adverse reactions.

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备注/Memo

备注/Memo:
基金项目:陕西省科技厅课题(2020JM-673)
更新日期/Last Update: 2024-07-09