[1]候 咪,霍涌波,赵秀秀,等.针刺联合行气活血散结方治疗乳腺增生疗效观察[J].陕西中医,2024,(9):1245-1248.[doi:DOI:10.3969/j.issn.1000-7369.2024.09.022]
　HOU Mi,HUO Yongbo,ZHAO Xiuxiu,et al.Observation on the therapeutic effect of acupuncture combined with Xingqi Huoxue Sanjie formula in the treatment of Mammary Gland Hyperplasia[J].,2024,(9):1245-1248.[doi:DOI:10.3969/j.issn.1000-7369.2024.09.022]
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针刺联合行气活血散结方治疗乳腺增生疗效观察
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2024年9期
页码:
1245-1248
栏目:
长安医学
出版日期:
2024-09-05

文章信息/Info

Title:
Observation on the therapeutic effect of acupuncture combined with Xingqi Huoxue Sanjie formula in the treatment of Mammary Gland Hyperplasia
作者:
候 咪; 霍涌波; 赵秀秀; 闫 龙; 王 丹; 兰雪琴
(延安市中医医院,陕西 延安 716000)
Author(s):
HOU Mi; HUO Yongbo; ZHAO Xiuxiu; YAN Long; WANG Dan; LAN Xueqin
(Yan'an Hospital of Traditional Chinese Medicine,Yan'an 716000,China)
关键词:
乳腺增生症;  陕北霍氏流派;  行气活血散结方;  雌二醇;  孕激素;  钼靶
Keywords:
Breast hyperplasia;  Huoshi School in northern Shaanxi;  Xingqi Huoxue Sanjie formula;  Estradiol;  Progesterone;  Molybdenum target
分类号:
R 655.8
DOI:
DOI:10.3969/j.issn.1000-7369.2024.09.022
文献标志码:
A
摘要:
目的:观察行气活血散结方联合针刺治疗乳腺增生症(MGH)的临床疗效及对患者血清雌二醇(E2)和孕激素(P)、乳腺钼靶分级、乳痛及肿块的影响。方法:将60例MGH患者采用随机数字表法分为对照组和观察组,对照组采用针刺治疗,选取双侧合谷、太冲、足三里、期门、丰隆、三阴交穴及肿块周围围刺,隔日1次,1个月为1疗程,共治疗3个月,观察组在针刺治疗基础上配合口服行气活血散结方,每日1剂,水煎400 ml分早晚温服,每次连服7～10 d,3次为1个疗程,共治疗3个月。比较两组患者治疗有效率、E2、P水平变化及钼靶分级变化、乳痛及乳房肿块变化。结果:治疗后,观察组总有效率高于对照组(P<0.05)。治疗后,两组患者E2、乳房疼痛及肿块评分较治疗前均降低,钼靶BI-RADS分级均降级,P水平升高,且观察组改善幅度较对照组更明显(P<0.05)。结论:行气活血散结方联合针刺对MGH患者有提升疗效、促进雌孕激素趋于正常、缓解乳房疼痛、缩小肿块范围的作用,可改善MGH患者生活质量。
Abstract:
Objective:To observe the clinical efficacy of Xingqi Huoxue Sanjie Formula combined with acupuncture in the treatment of Mammary Gland Hyperplasia(MGH),and its effects on serum Estradiol(E2)and Progesterone(P),breast molybdenum target grading,breast pain,and masses in patients.Methods:60 cases of MGH patients were randomly divided into control group and observation group,30 cases respectively.The control group were treated with acupuncture,the acupoints selection were bilateral Hegu,Taichong,Zusanli,Qimen,Fenglong,Sanyinjiao,and peri-puncture treatment around the breast lump,once every other day,one month as a course of treatment,totally 3 courses.In addition,the observation group received oral administration of the Xingqi Huoxue Sanjie formula,one dose per day,and 400 ml of water decoction divided into morning and evening warm drinks.Each dose was taken continuously for 7～10 days,3 times as a course of treatment,totally 3 courses.Compare the treatment efficacy,changes in E2 and P levels,molybdenum target grading,breast pain,and breast mass changes between control group and observation group.Results:Compared with the control group,the total effective rate of the observation group was significant(P<0.05).The E2,breast pain,and mass scores of both groups of patients decreased compared to before treatment.The molybdenum target BI-RADS grading was downgraded,and the P level increased.The observation group was statistically significant(P<0.05).Conclusion:The combination of Xingqi Huoxue Sanjie Formula and acupuncture has the effect of improving the therapeutic effect,promoting the normalization of E2/P hormones,alleviating breast pain,and reducing the range of tumors in MGH patients,which can improve the quality of life of MGH patients.

参考文献/References:

[1] 马薇,金泉秀,吴云飞,等.乳腺增生症诊治专家共识[J].中国实用外科杂志,2016,36(7):759-762.
[2] 左文述.现代乳腺肿瘤学[M].2版.济南:山东科学技术出版社,2006:1382-1389.
[3] 张保宁.乳腺肿瘤学[M].北京:人民卫生出版社,2013:453-456.
[4] 宿娜,山周琦玥,辛毅.乳腺癌患者426例临床特征及危险因素分析[J].陕西医学杂志,2023,52(12):1707-1710.
[5] 中华中医药学会.中医外科常见病诊疗指南[M].中国中医药出版社,2012:30-31.
[6] 刘胜,王怡,吴春宇,等.中西医结合临床诊疗乳腺增生专家共识[J].中华中医药杂志,2023,38(3):1159-1164.
[7] 于慧会,朱博,关磊,等.城市健康体检人群乳腺增生患病情况及影响因素的研究[J].中国临床医生杂志,2019,47(4):439-442.
[8] 曾婷婷,张还珠.健康体检人群乳腺疾病筛查结果分析[J].广州医科大学学报,2020,48(3):24-28.
[9] 高秉钧.疡科心得集[M].北京:人民卫生出版社,2006:55.
[10] 罗润佳,王星宇,徐茜茜,等.从明清古代文献论乳腺增生症与乳腺癌的关系[J].中国医药导报,2021,18(11):141-144.
[11] 王雨青,孙霃平,刘胜.从“乳为肝窍”论治乳房疾病[J].陕西中医,2022,43(7):929-931,949.
[12] 刘青松,李微,张怡,等.基于数据挖掘探讨“柴胡劫肝阴”的相杀配伍内涵[J].中草药,2022,53(14):4428-4436.
[13] 李静,何牟,李玲,等.白术挥发油化学成分及药理作用研究进展[J].中成药,2024,46(3):881-889.
[14] 郭娜.夏枯草颗粒对气滞血瘀证乳腺增生模型大鼠下丘脑-垂体-性腺相关激素分泌和单胺类神经递质含量的影响[J].中医临床研究,2017,9(36):97-100.
[15] 谭文超,张艳.黄芪多糖对乳腺癌细胞抑制作用机制研究[J].辽宁中医药大学学报,2024,26(3):8-12.
[16] 杨甫臣,张世超.针药并用对肝郁痰凝型乳腺增生病患者内分泌激素与血管生成因子的影响[J].上海针灸杂志,2021,40(6):709-714.
[17] 闫智会,王玉,梁亮.针刺配合督灸治疗气郁痰阻型乳腺增生的疗效观察[J].上海针灸杂志,2021,40(2):184-188.
[18] 赵娴,候咪.针刺结合乳乐冲剂对乳腺增生大鼠乳房组织、泌乳素及其受体表达的影响[J].中国针灸,2017,37(12):1309-1314.
[19] 冯春,李丽,宫凤英,等.针刺联合自拟乳癖祛瘀汤治疗血瘀痰凝型乳腺增生临床研究[J].中西医结合研究,2021,13(1):11-13,18.
[20] 张潞,郭新荣,王卫刚,等.国医大师郭诚杰运用乳乐方治疗乳腺增生病经验[J].陕西中医,2021,42(2):232-234.
[21] 卢庚辰,于振邦.《针灸大成》中期门穴的临床应用探析[J].中国民间疗法,2023,31(15):21-23.
[22] 牟东晓,杨峰.追本溯源,穷流知变:“丰隆治痰”考证[J].中国针灸,2021,41(9):1036-1042,1054.
[23] 毕富玺,闫颖,马静,等.针刺关元-三阴交对DOR患者卵巢储备功能及卵巢血流灌注的影响[J].罕少疾病杂志,2024,31(1):95-96.
[24] 张晓彤,张卫华.国医大师郭诚杰应用围刺加辨证取穴针法治疗MGH经验撷要[J].时珍国医国药,2022,33(7):1755-1756.
[25] 卢仙球,翟栋,陈利芳,等.经络辨证针刺法治疗乳腺增生病的临床观察[J].广州中医药大学学报,2021,38(12):2669-2674.
[26] 蔡康林,张婧恺,冉亮弟,等.柴胡-白芍配伍抗抑郁药理作用机制研究进展[J].实用医学杂志,2024,40(4):447-452.

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备注/Memo

备注/Memo:
基金项目:陕西省第二批中医学术流派传承工作室建设项目——陕北霍氏中医内科学术流派传承工作室(SXZYLP-2024017); 陕西省中医药管理局科研项目(2021-GJ-LC024)
更新日期/Last Update: 2024-09-09