[1]刘安琪,唐学贵.枳实对慢传输型便秘的药理作用及配伍应用研究现状[J].陕西中医,2025,46(2):277-280.[doi:DOI:10.3969/j.issn.1000-7369.2025.02.028]
　LIU Anqi,TANG Xuegui.Current research on the pharmacological effect of Citrus aurantium on slow-transit constipation and clinical compatibility[J].,2025,46(2):277-280.[doi:DOI:10.3969/j.issn.1000-7369.2025.02.028]
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枳实对慢传输型便秘的药理作用及配伍应用研究现状
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
46
期数:
2025年2期
页码:
277-280
栏目:
综 述
出版日期:
2025-02-05

文章信息/Info

Title:
Current research on the pharmacological effect of Citrus aurantium on slow-transit constipation and clinical compatibility
作者:
刘安琪; 唐学贵
(川北医学院附属医院,四川 南充 637000)
Author(s):
LIU Anqi; TANG Xuegui
(Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,China)
关键词:
枳实;  慢传输;  便秘;  药理作用;  配伍应用;  研究现状
Keywords:
Citrus aurantium;  Slow transmission;  Constipation;  Pharmacological effects;  Compatibility applications;  Research status
分类号:
R 256.35
DOI:
DOI:10.3969/j.issn.1000-7369.2025.02.028
文献标志码:
A
摘要:
枳实是中医临床常用的理气药,具有下气导滞,消积除痞的功效,可用于大便不通、积滞痞满等。慢传输型便秘(STC)是一种顽固的慢性便秘,病因机制复杂,与社会、心理、继发疾病和自身免疫问题等多方面因素有关。枳实可通过调节肠神经系统及信号通路; 减轻肠道炎症、调节肠道菌群; 调节水通道蛋白等在STC的治疗中发挥作用。并且枳实与其他药物的配伍应用在治疗中也能起到较好的效果,枳实通常与白术、芍药、厚朴等其他药物共同配伍,发挥协同作用,以达到增强药效的作用,提高疗效。本文通过对枳实的活性成分及其药理作用进行总结,并归纳梳理了枳实相关配伍在临床应用中的作用机制,以期为临床更安全有效地应用提供参考。
Abstract:
Citrus aurantium is a qi-regulating medicine commonly used in clinical Chinese medicine.It has the effect of lowering the qi,guiding stagnation,eliminating accumulated pimples,and can be used for constipation,stagnant pimples,etc.Slow transit constipation is a kind of stubborn chronic constipation with complex etiological mechanisms and is related to many factors such as social,psychological,secondary diseases and autoimmune problems.Citrus aurantium can play a role in the treatment of STC by regulating the enteric nervous system and signaling pathways; reducing intestinal inflammation,regulating intestinal flora; regulating aquaporins,etc.In addition,the compatibility of Citrus aurantium with other drugs can also achieve better results in treatment.Citrus aurantium is usually combined with Atractylodes,peony,Magnolia officinalis and other drugs to exert a synergistic effect to enhance the efficacy of the drug and improve the efficacy of the drug.Efficacy.This article summarizes the active ingredients and pharmacological effects of Citrus aurantium,and summarizes the mechanism of action of related compatibility of Citrus aurantium in clinical applications,in order to provide a reference for safer and more effective clinical applications.

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备注/Memo

备注/Memo:
[基金项目]国家自然科学基金资助面上项目(82074429)
更新日期/Last Update: 2025-02-08