[1]周 凡,陈福洪,慎朝旭,等.十三味消肿散联合股骨近端防旋髓内针内固定术治疗老年股骨粗隆间骨折临床研究[J].陕西中医,2025,46(3):335-338.[doi:DOI:10.3969/j.issn.1000-7369.2025.03.010]
 ZHOU Fan,CHEN Fuhong,SHEN Chaoxu,et al.Clinical study on treatment of elderly femoral intertrochanteric fractures with thirteen ingredient Xiaozhong powder external application combined with PFNA[J].,2025,46(3):335-338.[doi:DOI:10.3969/j.issn.1000-7369.2025.03.010]
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十三味消肿散联合股骨近端防旋髓内针内固定术治疗老年股骨粗隆间骨折临床研究
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
46
期数:
2025年3期
页码:
335-338
栏目:
临床研究
出版日期:
2025-03-05

文章信息/Info

Title:
Clinical study on treatment of elderly femoral intertrochanteric fractures with thirteen ingredient Xiaozhong powder external application combined with PFNA
作者:
周 凡1陈福洪1慎朝旭1曾 涛1申治富2
(1.川北医学院附属遂宁中医医院,四川 遂宁 402460; 2.川北医学院,四川 南充 637000)
Author(s):
ZHOU Fan1CHEN Fuhong1SHEN Chaoxu1ZENG Tao1SHEN Zhifu2
(1.Suining Hospital of Traditional Chinese Medicine Affiliated to North Sichuan Medical College,Suining 402460,China; 2.North Sichuan Medical College,Nanchong 637000,China)
关键词:
股骨转子间骨折 十三味消肿散 股骨近端防旋髓内针内固定术 炎症因子
Keywords:
Femoral intertrochanteric fracture Thirteen ingredient Xiaozhong powder Proximal femoral nail anti-rotation Inflammatory factors
分类号:
R 274.1
DOI:
DOI:10.3969/j.issn.1000-7369.2025.03.010
文献标志码:
A
摘要:
目的:探讨十三味消肿散外敷联合股骨近端防旋髓内针内固定术(PFNA)治疗老年股骨粗隆间骨折临床疗效。方法:选取165例老年股骨粗隆间骨折患者为研究对象,根据随机数字表法将其分为对照组、治疗组。对照组82例给予PFNA治疗,治疗组83例在对照组基础上予以十三味消肿散外敷。比较两组患者治疗前后患肢肿胀程度、疼痛度、髋关节功能、炎症因子水平、证候积分、并发症发生率。结果:治疗组与对照组术后肿胀、疼痛VAS评分较治疗前均下降,差异有统计学意义(P<0.05)。治疗组肿胀程度、疼痛VAS评分低于对照组,差异有统计学意义(均P<0.05)。治疗组术后7 d、1个月、1年髋关节功能Harris评分优于对照组,差异有统计学意义(均P<0.05)。治疗组治疗后炎症因子超敏C反应蛋白、白介素6低于对照组(均P<0.05)。治疗组治疗后局部瘀斑、刺痛、肿胀证候积分低于对照组(均P<0.05)。两组患者治疗后深静脉血栓、肺部感染、泌尿系感染、褥疮等并发症发生率比较,差异无统计学意义(均P>0.05)。结论:在PFNA基础上联合十三味消肿散外敷能提高老年股骨粗隆间骨折疗效,有效缓解患肢术后疼痛及肿胀,促进髋关节功能恢复,降低炎症因子水平。
Abstract:
Objective:To investigate clinical efficacy of external application of thirteen ingredient Xiaozhong powder combined with PFNA in treatment of intertrochanteric fracture of femur in the elderly.Methods:165 elderly patients with intertrochanteric fracture of femur were selected as research object,and randomly divided into control group and treatment group according to randomized numerical table method.82 cases in the control group were treated with proximal femoral nail anti-rotation(PFNA),and 83 cases in the treatment group were treated with external application of thirteen ingredient Xiaozhong powder on the basis of the control group.Compared degree of swelling,pain,hip function,inflammatory factor level,symptom score and complication rate of the affected limbs before and after the treatment of the two groups.Results:Postoperative swelling and pain VAS scores decreased in the observation and control groups compared before treatment,difference statistically significant(all P<0.05).The degree of swelling and pain VAS score decreased more significantly in the treatment group than in the control group,difference statistically significant(all P<0.05).The Harris score of hip joint function in the treatment group were better than those in the control group at 7 days,1 month and 1 year after surgery,difference statistically significant(all P<0.05).The levels of inflammatory factors hypersensitive C-reactive protein and interleukin 6 were significantly lower in the treatment group than in the control group after treatment(all P<0.05).Local ecchymosis,tingling and swelling symptom scores were significantly lower in the treatment group than those in the control group after treatment(all P<0.05).There was no significant difference in the incidence of complications such as deep vein thrombosis,pulmonary infection,urinary tract infection and decubitus ulcers between the two groups after treatment(P>0.05).Conclusion:The clinical efficacy of the addition of thirteen ingredient Xiaozhong powder on the basis of PFNA in the treatment of elderly intertrochanteric femur fracture was remarkable,which can effectively alleviate postoperative pain and swelling of affected limb,promote the recovery of the hip joint function,and reduce the level of inflammatory factors.

参考文献/References:

[1] 李紫阁,吴晶晶,周若愚,等.301例脆性髋部骨折回顾性研究及文献共现分析[J].中国骨质疏松杂志,2021,27(12):1810-1814.
[2] 许乐洋,范永前.老年股骨粗隆间骨折围术期的诊疗进展[J].老年医学与保健,2024,30(4):1184-1188.
[3] 覃欢,蓝海宏,胡宗,等.股骨粗隆间骨折的研究进展[J].中外医学研究,2019,17(15):186-188.
[4] 史图龙,严清,孙俊,等.不同手术方式治疗股骨粗隆间骨折的疗效及术后5年内死亡因素分析[J].蚌埠医学院学报,2024,49(9):1179-1183.
[5] 王广,鄢陵.股骨转子间骨折临床特点及治疗研究进展[J].临床骨科杂志,2024,27(4):601-606.
[6] 孙方贵,王德鑫,胡裕桐,等.股骨近端防旋髓内钉治疗股骨转子间骨折临床观察[J].中国骨伤,2017,30(10):915-919.
[7] 刘一儒,李楷,赵军,等.老年髋部骨折术后慢性疼痛的护理研究进展[J].实用医院临床杂志,2022,19(6):203-206.
[8] 林状诗,陈荣,殷锋.手术联合中药消肿汤治疗老年股骨粗隆间骨折患者的临床效果[J].中国中西医结合外科杂志,2021,27(6):896-899.
[9] 胥少汀,葛宝丰,徐印坎,等.实用骨科学[J].中国医刊,2009,44(6):56.
[10] 黄蓓.《证候类中药新药临床研究技术指导原则》发布[J].中医药管理杂志,2018,26(21):107.
[11] 国家中医药管理局.中药新药临床研究指导原则[M].北京:中国医药科技出版社,2002:233-237.
[12] 宋纯理.中国老年髋部及椎体骨折大数据分析报告[J].中华骨质疏松和骨矿盐疾病杂志,2024,17(4):303-307.
[13] 李家琛,杨朝晖.90岁以上股骨粗隆间骨折术后2年生存调查[J].中国矫形外科杂志,2024,32(10):884-888.
[14] 曹云平,邰金谷,陈涛,等.改良股骨近端抗旋髓内钉固定手术切口治疗股骨粗隆间骨折的疗效观察[J].生物骨科材料与临床研究,2024,21(5):36-41.
[15] 段超,周细江,王艺,等.中医特色的ERAS理念下多学科合作在高龄骨折患者围手术期的应用研究[J].中国中医急症,2024,33(9):1604-1607.
[16] 戴珉,潘奇华.续骨活血汤辅助手术治疗老年闭合性股骨转子间骨折临床研究[J].新中医,2022,54(3):95-99.
[17] 蒋伟兴,丁晓娟,王萍,等.骨科手术患者深静脉血栓的危险因素及改良Padua评分的预测价值[J].血管与腔内血管外科杂志,2023,9(6):687-690,700.
[18] 张艳磊,赵文军,张莹迪.以患者需求为导向的精细化护理干预在下肢深静脉血栓介入手术围手术期的应用价值[J].现代医药卫生,2025,41(1):148-151.
[19] 陈勇杰,方策.中西医治疗桡骨远端骨折后遗关节僵硬研究进展[J].河南中医,2023,43(5):804-810.
[20] 白洁,华雅琼,于晓丹.中医特色护理联合渐进式干预对骨质疏松性椎体压缩骨折患者恢复的影响[J].中国疗养医学,2024,33(12):70-74.
[21] 田好超,张宏军,李哲.股骨颈骨折的中西医研究现状及治疗进展[J].中医研究,2019,32(7):74-77.
[22] 王刚.辨证分期结合手术治疗老年股骨粗隆间骨折55例[J].陕西中医,2014,35(2):191-192.
[23] 王琳珏,郭锐,李钦宗,等.“筋揉骨正”中医特色疗法在股骨粗隆间骨折术后康复中的应用[J].世界中医药,2024,19(4):537-541.
[24] 林永飞,郭剑,蔡冬华,等.加味桃红四物汤对老年不稳定性股骨粗隆间骨折行人工股骨头置换术患者(气滞血瘀型)治疗中的应用价值[J].中国老年学杂志,2024,44(8):1850-1854.
[25] 张明清,孙莉莉,毕然,等.Charlson合并症指数对老年股骨粗隆间骨折术后并发症的预测效果[J].中华老年多器官疾病杂志,2023,22(3):176-180.

相似文献/References:

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备注/Memo

备注/Memo:
[基金项目]国家自然科学基金资助项目(82305415)
更新日期/Last Update: 2025-03-10