[1]张振丰,李春宁,杨琪琪,等.火针齐刺联合针刺治疗急性期膝骨关节炎寒湿痹阻证疗效研究[J].陕西中医,2025,46(7):968-972.[doi:DOI:10.3969/j.issn.1000-7369.2025.07.021]
　ZHANG Zhenfeng,LI Chunning,YANG Qiqi,et al.Clinical observation on treatment of acute-phase cold-damp paralytic-obstructive osteoarthritis of knee by fire-needle zigzag combined with acupuncture[J].,2025,46(7):968-972.[doi:DOI:10.3969/j.issn.1000-7369.2025.07.021]
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火针齐刺联合针刺治疗急性期膝骨关节炎寒湿痹阻证疗效研究

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
46
期数:
2025年7期
页码:
968-972
栏目:
针灸经络
出版日期:
2025-07-05

文章信息/Info

Title:
Clinical observation on treatment of acute-phase cold-damp paralytic-obstructive osteoarthritis of knee by fire-needle zigzag combined with acupuncture
作者:
张振丰1; 李春宁1; 杨琪琪1; 鲍亮1; 史思怡1; 陈希阳1; 李飞2
（1.安徽中医药大学研究生院，安徽 合肥 230012；2.安徽中医药大学第二附属医院，安徽 合肥 230061）
Author(s):
ZHANG Zhenfeng1; LI Chunning1; YANG Qiqi1; BAO Liang1; SHI Siyi1; CHEN Xiyang1; LI Fei2
(1.Graduate School of Anhui University of Traditional Chinese Medicine,Hefei 230012,China；2.The Second Affiliated Hospital of Anhui University of Chinese Medicine,Hefei 230061,China）
关键词:
膝骨关节炎; 火针齐刺; 急性期; 寒湿痹阻; 炎症因子; 骨代谢
Keywords:
Osteoarthritis of the knee; Fire needle flush; Acute phase; Cold-damp paralysis; Inflammatory factors; Bone metabolism
分类号:
R 245.31
DOI:
DOI:10.3969/j.issn.1000-7369.2025.07.021
文献标志码:
A
摘要:
目的：观察火针齐刺联合针刺治疗急性期膝骨关节炎（KOA）寒湿痹阻证的临床疗效。方法：将 70 例急性期寒湿痹阻型KOA患者随机分为对照组与观察组，各35例。对照组采用常规针刺治疗，穴取局部阿是穴、阴阳陵泉、内膝眼、犊鼻、鹤顶、梁丘、血海，均取双侧；观察组采用火针齐刺，取穴同上。两组均隔日1次，每周3次，共3周。于治疗前后比较两组视觉模拟评分（VAS）、西大略和麦克马斯特大学骨关节炎指数评分（WOMAC）、阳虚型体质量表评分，超声下髌上囊及关节腔积液情况，血清骨代谢指标骨保护素（OPG）、骨钙素（BGP），以及关节液炎症因子肿瘤坏死因子-α（TNF-α）、白细胞介素-6（IL-6）水平变化，并评估临床疗效。结果：治疗后，两组VAS、WOMAC、阳虚型体质量表评分降低（均P＜0.05），超声下髌上囊及关节腔积液深度减少（P＜0.05），血清OPG、BGP 水平升高，关节液TNF-α、IL-6水平降低，且观察组变化更显著（均P＜0.05）。观察组疗效优于对照组（均P＜0.05）。结论：火针齐刺能有效改善急性期寒湿痹阻型 KOA 患者阳虚型体质，减轻膝关节积液与疼痛，改善关节功能，降低炎症因子水平，提高骨代谢水平。
Abstract:
Objective:To observe clinical efficacy of fire needle Qi puncture combined with acupuncture in the treatment of acute-phase cold-damp paralytic-obstructive knee osteoarthritis (KOA).Methods:Seventy patients with acute-phase cold-damp paralytic obstruction type KOA were randomly assigned to control group and observation group,35 cases each.The control group were treated with conventional acupuncture,and the acupuncture points were localized to Ah Yes point,Yin Yang Ling Quan,Inner Knee Eye,Calvary Nose,Crane’s Nose,Liang Qiu,and Sea of Blood,all of which were taken bilaterally.The observation group were combined with the fire acupuncture,and the acupuncture points were the same as above.Both groups were treated once every other day,three times a week for three weeks.Before and after treatment,the visual analog score (VAS),Western Ontario and McMaster University Osteoarthritis Index Score (WOMAC),the scale score of Yang-deficient body type,and the ultrasonic suprapatellar bursa and joint cavity effusion were compared between the two groups.Changes in serum bone metabolism indexes osteoprotegerin (OPG),osteocalcin (BGP),and levels of joint fluid inflammatory factors tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6),as well as clinical efficacy.Results:After treatment,VAS,WOMAC,and Yang-deficient body mass scale scores were reduced in both groups (all P<0.05),the depth of ultrasound suprapatellar bursa and joint cavity effusion was reduced (P<0.05),the serum OPG and BGP levels were increased,and the levels of articular fluid TNF-α,and IL-6 were reduced,and the changes in the observation group were more significant (all P<0.05).The efficacy of the observation group was better than that in the control group (P<0.05).Conclusion:Fire needle Qi puncture can effectively improve Yang-deficiency type constitution of patients with acute-phase cold-damp paralytic obstruction type KOA,reduce knee joint effusion and pain,improve joint function,reduce the level of inflammatory factors,and improve bone metabolism.

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备注/Memo

备注/Memo:
国家青年岐黄学者支持项目（国中医药人教函〔2022〕256号）；安徽省自然科学基金资助面上项目（2308085MH297）；安徽省高等学校自然科学研究项目（2023AH040099）
更新日期/Last Update: 2025-07-09