[1]杜旭,童悦,袁海光,等.针刺联合拔罐治疗脾肾阳虚型慢性疲劳综合征及对患者血清白细胞介素-6、肿瘤坏死因子-α的影响研究[J].陕西中医,2025,46(10):1419-1424.[doi:DOI:10.3969/j.issn.1000-7369.2025.10.024]
　DU Xu,TONG Yue,YUAN Haiguang,et al.Study of acupuncture combined with cupping in the treatment of spleen-kidney-yang deficiency type chronic fatigue syndrome and its effect on IL-6 and TNF-α[J].,2025,46(10):1419-1424.[doi:DOI:10.3969/j.issn.1000-7369.2025.10.024]
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针刺联合拔罐治疗脾肾阳虚型慢性疲劳综合征及对患者血清白细胞介素-6、肿瘤坏死因子-α的影响研究

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
46
期数:
2025年10期
页码:
1419-1424
栏目:
针灸经络
出版日期:
2025-10-05

文章信息/Info

Title:
Study of acupuncture combined with cupping in the treatment of spleen-kidney-yang deficiency type chronic fatigue syndrome and its effect on IL-6 and TNF-α
作者:
杜旭1; 童悦1; 袁海光2; 王斌2; 张容超1; 刘海燕1; 袁瑞华1
（1.陕西中医药大学，陕西 咸阳 712046；2.陕西中医药大学附属医院，陕西 咸阳 712000）
Author(s):
DU Xu1; TONG Yue1; YUAN Haiguang2; WANG Bin2; ZHANG Rongchao1; LIU Haiyan1; YUAN Ruihua1
(1.Shaanxi University of Chinese Medicine,Xianyang 712046,China;2.Affiliated Hospital of Shaanxi University of Chinese Medicine,Xianyang 712000,China)
关键词:
慢性疲劳综合征; 脾肾阳虚证; 中医适宜技术; 针刺; 拔罐
Keywords:
Chronic fatigue syndrome; Deficiency syndrome of spleen and kidney yang; Appropriate techniques of traditional Chinese medicine; Acupuncture; Cupping
分类号:
R 872.7
DOI:
DOI:10.3969/j.issn.1000-7369.2025.10.024
文献标志码:
A
摘要:
目的：观察针刺、拔罐及二者联合对脾肾阳虚型慢性疲劳综合征患者的治疗效果及对血清白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)影响的差异。方法：对90例脾肾阳虚型慢性疲劳综合征患者采取随机数字表法进行分组，分为针刺组、拔罐组、针刺拔罐组，每组各30例。比较三组患者治疗前后中医证型量化积分表评分、疲劳量表(FS-14)评分，焦虑自评量表(SAS)评分和匹兹堡睡眠质量指数量表(PSQI)评分以及血清IL-6、TNF-α水平，并评估临床疗效。结果：治疗后，三组患者脾肾阳虚证候积分、FS-14积分、PSQI积分均低于治疗前(P＜0.05)，且针刺拔罐组降低水较其他两组更为明显(P＜0.05)，针刺组与拔罐组比较差异无统计学意义(P＞0.05)；三组患者SAS积分均低于治疗前(P＜0.05)，且针刺拔罐组与针刺组降低水平比较差异无统计学意义(P＞0.05)，且均优于拔罐组(P＜0.05)；三组患者血清水平IL-6均较治疗前降低，针刺拔罐组降低水平大于其他两组(P＜0.05)，针刺组与拔罐组比较差异无统计学意义(P＞0.05)；三组患者的血清TNF-α水平均较治疗前降低(P＜0.05)，针刺拔罐组降低水平与针刺组比较差异无统计学意义(P＞0.05)，且两组降低水平优于拔罐组(P＜0.05)。治疗后针刺组总有效率83.33%，拔罐组总有效率76.67%，针刺拔罐组总有效率93.33%，差异有统计学意义(P＜0.05)。结论：针刺联合拔罐治疗脾肾阳虚型慢性疲劳综合征患者疗效确切，可改善患者的相关症状及血清IL-6、TNF-α水平。
Abstract:
Objective:To observe the differences in the therapeutic effects of acupuncture,cupping and their combination on patients with chronic fatigue syndrome of spleen and kidney yang deficiency type,as well as their influences on the contents of serum interleukin-6 (IL-6) and tumor necrosis factor-α(TNF-α).Methods:Ninety patients with chronic fatigue syndrome of spleen and kidney yang deficiency type were grouped by random number table method,divided into acupuncture group,cupping group and acupuncture and cupping group,with 30 cases in each group.The scores of the Quantitative Score of traditional Chinese medicine syndrome types,the Fatigue Scale (FS-14),the Self-Rating Anxiety Scale (SAS),the Pittsburgh Sleep Quality Index (PSQI) Scale,as well as the levels of serum IL-6 and TNF-α before and after treatment were compared among the three groups of patients,and the clinical efficacy was evaluated.Results:After treatment,the scores of spleen and kidney yang deficiency syndrome,FS-14 score and PSQI score of the three groups of patients were all lower than those before treatment (P<0.05),and the reduction of water in the acupuncture and cupping group was more obvious than that in the other two groups (P<0.05),while there was no statistically significant difference between the acupuncture group and the cupping group (P>0.05).The SAS scores of the three groups of patients were all lower than those before treatment (P<0.05),and there was no statistically significant difference in the reduction level between the acupuncture and cupping group and the acupuncture group (P>0.05),and they were all better than the cupping group (P<0.05).The serum levels of IL-6 in the three groups of patients were all lower than those before treatment.The decrease level in the acupuncture and cupping group was greater than that in the other two groups (P<0.05),while there was no statistically significant difference between the acupuncture group and the cupping group (P>0.05).The serum TNF-α levels of the three groups of patients were all decreased compared with those before treatment (P<0.05).There was no statistically significant difference in the decreased level between the acupuncture and cupping group and the acupuncture group (P>0.05),and the decreased levels of the two groups were better than those of the cupping group (P<0.05).After the treatment,the total effective rate was 83.33% in the acupuncture group,76.67% in the cupping group,and 93.33% in the acupuncture and cupping group.The difference was statistically significant (P<0.05).Conclusion:Acupuncture combined with cupping therapy has a definite therapeutic effect on patients with chronic fatigue syndrome of spleen and kidney Yang deficiency type,and can improve the related symptoms and serum levels of IL-6 and TNF-α in patients.

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备注/Memo

备注/Memo:
陕西省中医药管理局课题（SZY-KJCYC-2023-011，173000223047/303）；陕西省教育厅课题（23JT006）
更新日期/Last Update: 2025-10-10