[1]李莎莎,龙小荣,刘芊芊,等.子午流注纳干法针刺中风后单侧偏瘫疗效研究[J].陕西中医,2026,(2):255-259.[doi:DOI:10.3969/j.issn.1000-7369.2026.02.020]
　LI Shasha,LONG Xiaorong,LIU Qianqian,et al.Clinical study on therapeutic effect of Ziwu Liuzhu Nagan acupuncture on unilateral hemiplegia after stroke[J].,2026,(2):255-259.[doi:DOI:10.3969/j.issn.1000-7369.2026.02.020]
点击复制

子午流注纳干法针刺中风后单侧偏瘫疗效研究

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2026年2期
页码:
255-259
栏目:
针灸经络
出版日期:
2026-02-05

文章信息/Info

Title:
Clinical study on therapeutic effect of Ziwu Liuzhu Nagan acupuncture on unilateral hemiplegia after stroke
作者:
李莎莎1; 龙小荣1; 刘芊芊1 ; 杨松2; 蒋学余2
（1.湖南中医药大学，湖南 长沙 410208；2.岳阳市中医医院，湖南 岳阳 414000）
Author(s):
LI Shasha1; LONG Xiaorong1; LIU Qianqian1 ; YANG Song2; JIANG Xueyu2
（1.Hunan University of Chinese Medicine,Changsha 410208,China；2.Yueyang Hospital of Traditional Chinese Medicine,Yueyang 414000,China）
关键词:
中风; 单侧偏瘫; 上守神理论; 子午流注纳干法; 辰时; 运动功能; 炎症因子
Keywords:
Stroke; Unilateral hemiplegia; Theory of Shangshou Shen; Ziwu Liuzhu Nagan; Chenshi; Motor function; Inflammatory factor
分类号:
R 255.2
DOI:
DOI:10.3969/j.issn.1000-7369.2026.02.020
文献标志码:
A
摘要:
目的：观察基于上守神理论运用子午流注纳干法针刺治疗中风后单侧偏瘫疗效。方法：把120例患者随机分为观察组和对照组,两组各60例。观察组基于上守神理论运用子午流注纳干法，按照日、时的天干选择不同经脉的五输穴于辰时针刺治疗，每日1次，每次30 min。对照组穴取常规穴位进行针刺,不限定针刺时间，每日1次，每次30 min。各组均每周连续干预6 d，共干预2周。比较两组疗效，观察两组肢体功能、脑结构功能改善情况、炎症因子调控水平、日常生活活动能力，并评估其安全性。结果：与对照组比较，观察组FMA评分更高(P＜0.05)。治疗后，两组脑功能重塑在M1区激活体积、胼胝体FA值均高于治疗前，与对照组比较，观察组在M1区激活体积、胼胝体FA值改善幅度更高(均P＜0.05)。治疗后，两组炎症因子TNF-α、D-二聚体水平均低于治疗前，与对照组比较，观察组TNF-α、D-二聚体水平更低，差异有统计学意义(均P＜0.05)。治疗后，两组BI评分高于治疗前，与对照组比较，观察组BI评分更高(P＜0.05)。研究期间两组均未出现严重不良反应。结论：基于上守神理论运用子午流注纳干法择时选经取穴进行针刺治疗,能有效改善中风单侧偏瘫患者的运动功能，促进脑功能重塑及炎症调控作用，并能提高患者日常生活能力，促进偏瘫功能恢复。
Abstract:
Objective:Efficacy of acupuncture based on theory of Shangshou Shen and application of Ziwu Liuzhu and Nagan methods in treating hemiplegia after stroke was observed.Methods:120 patients were randomly divided into observation group and control group,with 60 cases in each group.The observation group were treated with acupuncture based on theory of Shangshou Shen and Ziwu Liuzhu and Nagan methods.Different meridians’ Five Shu points were selected according to the day and hour’s heavenly stems,and acupuncture was performed at the Chenshi.once a day for 30 minutes.The control group were treated with conventional acupuncture at specific points without time restrictions,once a day for 30 minutes.Both groups were intervened continuously for 6 days a week for 2 weeks.The efficacy of the two groups were compared,and improvement of limb function,brain structure and function,inflammatory factor regulation levels,and activities of daily living were observed.Safety was also evaluated.Results:After treatment FMA score of the observation group was higher than that in the control group (P＜0.05).After treatment,the activation volume of the M1 area and the FA value of the corpus callosum in both groups were higher than before treatment,and the improvement in the observation group was greater than that in the control group (all P＜0.05).After treatment,the levels of TNF-α and D-Dimer in both groups were lower than before treatment,and levels in the observation group were lower than those in the control group,significant differences(all P＜0.05).After treatment,the BI scores of both groups were higher than before treatment,and the BI score of the observation group was higher than that in the control group (P＜0.05).No serious adverse reactions occurred in either group during the study period.Conclusion:Acupuncture based on theory of Shangshou Shen and the application of Ziwu Liuzhu and Nagan methods for selecting meridians and points at specific times can effectively improve motor function of patients with hemiplegia after stroke,promote brain function remodeling and inflammation regulation,and enhance the patients’ ability to perform activities of daily living,thereby promoting the recovery of hemiplegia function.

参考文献/References:

[1]曹静,许辛寅.针刺调节肠道菌群治疗中风的“神经-内分泌-免疫”机制研究进展[J].湖北中医药大学学报,2025,27(1):122-125.
[2]韩燕.量化食物稠度对脑卒中吞咽功能障碍病人预防误吸的效果[J].循证护理,2022,8(5):708-710.
[3]CIEZA A,CAUSEY K,KAMENOV K,et al.Global estimates of the need for rehabilitation based on the global burden of disease study 2019:A systematic analysis for the global burden of disease Study 2019[J].Lancet,2021,396(10267):2006-2017.
[4]王陇德,彭斌,张鸿祺,等.《中国脑卒中防治报告2020》概要[J].中国脑血管病杂志,2022,19(2):136-144.
[5]陆家卉,阴秀春,李元婧.头部围针、体针联合作业疗法对脑卒中后上肢痉挛性偏瘫患者认知、肌痉挛和患肢精细运动的影响[J].新中医,2025,57(4):83-87.
[6]李丽丽.血府逐瘀汤治疗脑卒中后肌张力增高疗效及对患者运动功能的影响[J].陕西中医,2021,42(4):449-451.
[7]覃华,杨西宁,谭奕,等.基于Brunnstrom分期的脑卒中居家康复训练方案的建立与应用[J].广西中医药大学学报,2022,25(6):61-66.
[8]黄坤,杨莉,赵程峰.基于Bobath理念下运动治疗结合呼吸引导训练对脑卒中偏瘫患者下肢功能恢复的临床效果观察[J].贵州医药,2023,47(4):671-672.
[9]徐雪迪,徐雪梅,陈和木,等.神经肌肉电刺激联合Rood技术对脑卒中软瘫期患者上肢功能的影响[J].安徽医学,2022,43(9):995-998.
[10]吴奇,程光宇,薛国威,等.针灸治疗脑卒中后肌张力增高的研究进展[J].世界中西医结合杂志,2024,19(12):2530-2534.
[11]葛冉,孙志岭,周丹萍,等.子午流注理论治疗痹证研究述评[J].中医学报,2015,30(5):761-763.
[12]罗桂青,李磊.子午流注针法治疗中风病临床研究进展[J].光明中医,2013,28(1):221-223.
[13]袁雷,郭玮华,吴绍华.子午流注纳甲针法治疗中风后遗症(气虚血瘀证)的临床观察[J].中国中医急症,2017,26(8):1436-1438.
[14]赵玲娟,刘岩,文力.《中国急性缺血性卒中诊治指南2023》治疗策略解析[J].临床药物治疗杂志,2024,22(11):1-6.
[15]王立童,王鑫,代永利,等.子午流注纳支针刺法结合康复训练治疗脑卒中患者肢体功能障碍的临床观察[J].上海中医药杂志,2018,52(9):47-50.
[16]王启才.针灸治疗学[M].北京：中国中医药出版社,2007:63-64.
[17]WANG M,WEI X,YU M,et al.Cognitive impairment in mild traumatic brain injury:A diffusion kurtosis imaging and volumetric study[J].Acta Radiol,2022,63(4):504-512.
[18]张瑜.针刺优化方案治疗脑卒中患者运动功能障碍的疗效观察[D].广州：南方医科大学,2024.
[19]宁长青,曹彦俊,冯伟,等.针灸推拿综合康复疗法改善脑卒中患者运动功能临床研究[J].上海中医药杂志,2013,47(10):47-48.
[20]TONI D,ARGENTINO C,GENTILE M,et al.Circadian variation in the onset of acute cerebral ischemia:Ethiopathogenetic correlates in 80 patients given angiography[J].Chronobiol Int,1991,8(5):321-326.
[21]日色雄一.日本考证学派《灵枢》研究之考察[D].北京：北京中医药大学,2011.
[22]董新刚,贾奎.吴标教授从脾辨治中风后失语经验[J].中医学报,2015,30(8):1145-1147.
[23]付艾妮,朱书秀.针刺之要重在调神——对《内经》中“上守神”涵义的理解[J].中医药临床杂志,2009,21(5):383-384.
[24]乔红伟,张智龙.针刺“守神”思想之浅析[J].中医药导报,2018,24(4):78-79.
[25]张蕊,李和平.子午流注纳甲法治疗缺血性中风后遗症研究进展[J].河南中医,2013,33(6):960-962.
[26]CHEN L,FANG J,MA R,et al.Additional effects of acupuncture on early comprehensive rehabilitation in patients with mild to moderate acute ischemic stroke:A multicenter randomized controlled trial[J].BMC Complement Altern Med,2016,16:226.
[27]王春南,马铁明.针灸与振动训练对缺血缺氧性脑病大鼠细胞炎症反应的研究[J].中华中医药学刊,2017,35(6):1502-1505.

相似文献/References:

[1]倪建俐,黄 姝,袁 晴△.中医特色疗法治疗中风后肢体功能障碍研究进展*[J].陕西中医,2020,(9):1339.[doi:DOI:10.3969/j.issn.1000-7369.2020.09.045]
[2]张晓霞,杨 峥△,赵 亭.风三针治疗中风后吞咽障碍临床研究*[J].陕西中医,2020,(10):1504.[doi:DOI:10.3969/j.issn.1000-7369.2020.10.046]
　ZHANG Xiaoxia,YANG Zheng,ZHAO Ting..The clinical effect of “three wind needles” in patients with dysphagia after stroke[J].,2020,(2):1504.[doi:DOI:10.3969/j.issn.1000-7369.2020.10.046]
[3]郭 爽,于存娟,陈婷婷.星蒌承气汤治疗中风病痰热腑实证疗效及对患者生物学指标和血浆内毒素脂多糖的影响[J].陕西中医,2022,(5):592.[doi:DOI:10.3969/j.issn.1000-7369.2022.05.011]
　GUO Shuang,YU Cunjuan,CHEN Tingting.Effect of Xinglou Chengqi decoction on biological indexes and plasma LPS of patients with stroke disease[J].,2022,(2):592.[doi:DOI:10.3969/j.issn.1000-7369.2022.05.011]
[4]兰 谢,余帅江.温针灸对中风后遗症患者血清炎症因子的影响[J].陕西中医,2022,(7):954.[doi:DOI:10.3969/j.issn.1000-7369.2022.07.035]
　LAN Xie,YU Shuaijiang.Effects of warm acupuncture and moxibustion on serum inflammatory factor in patients with stroke sequelae[J].,2022,(2):954.[doi:DOI:10.3969/j.issn.1000-7369.2022.07.035]
[5]赵康如,柳 雪,范兆鹏,等.针灸联合门德尔松手法对中风后吞咽困难患者吞咽功能的影响[J].陕西中医,2022,(7):958.[doi:DOI:10.3969/j.issn.1000-7369.2022.07.036]
　ZHAO Kangru,LIU Xue,FAN Zhaopeng,et al.Effect of acupuncture and Mendelssohn's manipulation on the improvement of swallowing function in patients with dysphagia after stroke[J].,2022,(2):958.[doi:DOI:10.3969/j.issn.1000-7369.2022.07.036]
[6]王友刚,高大红,柳 刚,等.压灸足运感区联合盆底肌肉训练对中风后尿失禁患者临床症状、膀胱残余尿量及生活质量的影响[J].陕西中医,2023,(5):663.[doi:DOI:10.3969/j.issn.1000-7369.2023.05.030]
　WANG Yougang,GAO Dahong,LIU Gang,et al.Effects of foot massage and pelvic floor muscle training on clinical symptoms,residual urine volume of bladder and quality of life of patients with urinary incontinence after stroke[J].,2023,(2):663.[doi:DOI:10.3969/j.issn.1000-7369.2023.05.030]
[7]陈雨菲,李小黎,张 婧,等.温针灸治疗气虚血瘀型中风后遗症研究进展[J].陕西中医,2023,(8):1150.[doi:DOI:10.3969/j.issn.1000-7369.2023.08.036]
[8]梁艳桂,吴海科,黄耀渠,等.针灸不同穴位组治疗中风后假性球麻痹吞咽功能障碍疗效研究[J].陕西中医,2024,(3):411.[doi:DOI:10.3969/j.issn.1000-7369.2024.03.029]
　LIANG Yangui,WU Haike,HUANG Yaoqu,et al.Curative effect study on different acupuncture point on swallowing dysfunction caused by pseudobulbar palsy after stroke[J].,2024,(2):411.[doi:DOI:10.3969/j.issn.1000-7369.2024.03.029]
[9]张 敌,王彦华,陈昺伃.脑卒中半身不遂中医病机探析[J].陕西中医,2024,(7):947.[doi:DOI:10.3969/j.issn.1000-7369.2024.07.019]
　ZHANG Di,WANG Yanhua,CHEN Bingyu.Traditional Chinese medicine pathogenesis of stroke hemiplegia[J].,2024,(2):947.[doi:DOI:10.3969/j.issn.1000-7369.2024.07.019]
[10]罗春梅,李佩芳,刘 霞,等.针刺夹脊穴联合通督调神针刺治疗中风后平衡障碍临床研究[J].陕西中医,2024,(9):1262.[doi:DOI:10.3969/j.issn.1000-7369.2024.09.026]
　LUO Chunmei,LI Peifang,LIU Xia,et al.Clinical study on acupuncture at Jiaji point combined with Tongdu Tiaoshen acupuncture in the treatment of post-stroke balance disorders[J].,2024,(2):1262.[doi:DOI:10.3969/j.issn.1000-7369.2024.09.026]

备注/Memo

备注/Memo:
湖南省自然科学基金资助项目（2024JJ7603）；湖南省中医药管理局局市（州）联合中医药科研课题（E2023039，E2023040）；湖南省卫生健康委科研课题（D202304079413）；湖南中医药大学校院联合基金资助项目（2023XYLH062，2023XYLH065，2023XYLH066）
更新日期/Last Update: 2026-02-09