[1]任耀龙,吉 锋,李星星,等.保元通脉胶囊改善PCI气虚血瘀证患者右心室纵向应变疗效研究[J].陕西中医,2026,(5):614-618.[doi:DOI:10.3969/j.issn.1000-7369.2026.05.006]
　REN Yaolong,JI Feng,LI Xingxing,et al.Study on therapeutic effect of Baoyuan Tongmai capsules on improving right ventricular longitudinal strain in patients with Qi deficiency and blood stasis syndrome after PCI[J].,2026,(5):614-618.[doi:DOI:10.3969/j.issn.1000-7369.2026.05.006]
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保元通脉胶囊改善PCI气虚血瘀证患者右心室纵向应变疗效研究

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2026年5期
页码:
614-618
栏目:
临床研究
出版日期:
2026-05-05

文章信息/Info

Title:
Study on therapeutic effect of Baoyuan Tongmai capsules on improving right ventricular longitudinal strain in patients with Qi deficiency and blood stasis syndrome after PCI
作者:
任耀龙1; 吉 锋1; 李星星1; 胡龙涛2
（1.陕西中医药大学附属医院，陕西 咸阳 712021；2.陕西中医药大学第二附属医院，陕西 咸阳 712099）
Author(s):
REN Yaolong1; JI Feng1; LI Xingxing1; HU Longtao2
（1.The Affiliated Hospital of Shaanxi Chinese Medicine University，Xianyang 712021，China；2.The Second Affiliated Hospital of Shaanxi University of Chinese Medicine，Xianyang 712099，China）
关键词:
急性心肌梗死; 保元通脉胶囊; 经皮冠状动脉介入治疗; 二维斑点追踪; 心室功能
Keywords:
Cute myocardial infarction; Baoyuan Tongmai capsule; Percutaneous coronary intervention; Two-dimensional spot tracking; Ventricular function
分类号:
R541
DOI:
DOI:10.3969/j.issn.1000-7369.2026.05.006
文献标志码:
A
摘要:
目的：基于二维斑点追踪技术（2D-STI）定量评价保元通脉胶囊改善急性前壁ST段抬高型心肌梗死（STEMI）气虚血瘀证患者直接PCI术后右心室（RV）纵向应变价值。方法：将82例首次急性前壁STEMI行直接PCI术的患者随机分为观察组（42例）与对照组（40例），两组患者术后均给予规范抗凝、抗血小板聚集、调脂、扩冠、营养心肌等治疗。观察组在规范治疗基础上加用口服保元通脉胶囊，采用2D-STI技术对比分析治疗前后RV整体纵向应变（RVGLS）、RV整体径向峰值应变（RVGRS）、RV心内膜纵向峰值应变（RVGLSendo）、RV游离壁与室间隔收缩期各节段纵向峰值应变（LS）及其应变率（LSR）。结果：观察组治疗后RVGLS、RVGRS、RVGLSendo均较本组治疗前显著改善，且改善幅度均优于对照组（P＜0.05）。观察组治疗后右心室游离壁各节段LS均较治疗前降低，且中间段、心尖段LS降低幅度优于对照组（P＜0.05）。观察组治疗后室间隔心尖段LS较治疗前显著降低，且优于对照组（P＜0.05）。观察组治疗后右心室游离壁中间段LSR及室间隔基底段LSR均较治疗前增加（P＜0.05），且增加幅度均大于对照组（P＜0.05）。结论：保元通脉胶囊可显著改善急性前壁STEMI直接PCI术后患者RV功能。
Abstract:
Objective:To quantitatively evaluate value of Baoyuan Tongmai capsules in improving right ventricular (RV) longitudinal strain in patients with Qi deficiency and blood stasis syndrome after direct percutaneous coronary intervention (PCI) for acute anterior ST-segment elevation myocardial infarction (STEMI) based on two-dimensional speckle tracking imaging (2D-STI).Methods:82 patients with first acute anterior STEMI who underwent direct PCI were randomly divided into observation group (42 cases) and control group (40 cases).Both groups were given standardized anticoagulation,antiplatelet aggregation,lipid regulation,coronary dilation,and myocardial nutrition treatment after the operation.The observation group was additionally treated with oral Baoyuan Tongmai capsules.2D-STI was used to compare and analyze the RV global longitudinal strain (RVGLS),RV global radial peak strain (RVGRS),RV endocardial longitudinal peak strain (RVGLSendo),longitudinal peak strain (LS) and its strain rate (LSR) of each segment of the RV free wall and interventricular septum during systole before and after treatment.Results:After treatment,RVGLS,RVGRS,and RVGLSendo in the observation group were significantly improved compared with those before treatment,and the improvement was better than that in the control group (P＜0.05).After treatment,the LS of each segment of the RV free wall in the observation group was lower than that before treatment,and the reduction in the middle and apical segments was better than that in the control group(P＜0.05).After treatment,LS of the apical segment of the interventricular septum in the observation group was significantly lower than that before treatment,and better than that in the control group (P＜0.05).After treatment,the LSR of the middle segment of the RV free wall and the basal segment of the interventricular septum in the observation group was increased compared with those before treatment (P＜0.05),and the increase greater than that in the control group (P＜0.05).Conclusion:Baoyuan Tongmai capsules can significantly improve RV function in patients with acute anterior STEMI after direct PCI.

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备注/Memo

备注/Memo:
国家自然科学基金资助项目（82405140）；秦创原中医药产业创新聚集区项目（L2024-QCY-ZYYJJQ-X223）；陕西省重点研发计划-重点产业创新链（群）项目（2024SF-ZDCYL-03-21）；陕西省教育厅科研项目（23JS012）；陕西省咸阳市科技局重点研发计划项目（2021ZDYF-SF-0034，L2023-ZDYF-SF-047）；陕西省省级院士工作站建设项目-吴以岭院士工作站（陕组通字〔2019〕49号-30）；陕西省教育厅重点实验室项目（22JS005）
更新日期/Last Update: 2026-05-05