[1]余积洁,胡作伦△,许克难.加减皱肺汤对慢性阻塞性肺疾病稳定期患者生存质量影响[J].陕西中医,2018,(10):1381-1383.
　Yu Jijie,Hu Zuolun,Xu Kenan..Quality of life in patients with chronic obstructive pulmonary disease in stable stage treated by modified Zhoufei decoction[J].,2018,(10):1381-1383.
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加减皱肺汤对慢性阻塞性肺疾病稳定期患者生存质量影响
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2018年10期
页码:
1381-1383
栏目:
临床研究
出版日期:
2018-12-31

文章信息/Info

Title:
Quality of life in patients with chronic obstructive pulmonary disease in stable stage treated by modified Zhoufei decoction
文章编号:
DOI: 10.3969/j.issn.1000-7369.2018.10.020
作者:
余积洁; 胡作伦△; 许克难
湖北省荆门市中医医院(市石化医院)( 荆门〖HTF〗448000)
Author(s):
Yu Jijie; Hu Zuolun; Xu Kenan.
Jingmen Chinese Medicine Hospital (City Petrochemical Hospital)in Hunan Province（Jingmen448000）
关键词:
肺疾病; 慢性阻塞性/中西医结合疗法@加减皱肺汤生活质量
Keywords:
Key words Pulmonary disease; chronic obstructive/ integrated Chinese traditional and western medicine therapy@Modified Zhoufei decoctionQuality of life
分类号:
R563.91
文献标志码:
A
摘要:
摘要 目的：研究加减皱肺汤对慢性阻塞性肺疾病稳定期患者生存质量的影响。方法：选择94例慢性阻塞性肺疾病稳定期患者，将其随机分为对照组和观察组各47例。对照组不给予干预治疗，观察组口服加减皱肺汤，连续治疗6个疗程（1个疗程30 d），观察对比两组患者生存质量。结果：治疗后两组生存质量总分（TMS）、日常生活能力因子分(F1S)、社会活动状况因子分(F2S)、抑郁心理症状因子分（F3S）、焦虑心理症状因子分（F4S）均明显改善，与治疗前对比(P＜0.05)，且观察组改善比对照组明显，差异有统计学意义(P＜0.05)。治疗后两组临床症状（咳嗽、喘息、气短、咯痰）评分明显降低，与治疗前对比(P＜0.05)，且观察组下降幅度比对照组明显，差异有统计学意义(P＜0.05)。治疗后两组最大肺活量(VCmax)、1秒钟用力呼气量（FEV1）、1秒量比用力肺活量(FEV1/FVC)、最大呼气中段平均流速(MMEF)、呼气峰值流速(PEF)显著改善，与治疗前对比(P＜0.05)，且观察组改善比对照组明显，差异有统计学意义(P＜0.05)。两组患者均未发生严重不良反应，差异无统计学意义(P＞0.05)。结论：加减皱肺汤对慢性阻塞性肺疾病稳定期患者生存质量具有积极的影响，可提高患者生存质量，改善临床症状，延缓肺功能下降趋势，值得临床应用。
Abstract:
Abstract Objective ：To study the effect of modified Zhoufei decoction on the quality of life in patients with chronic obstructive pulmonary disease in stablephase.Methods ： 94 cases of patients with stable chronic obstructive pulmonary disease were randomly divided into control group and observation group，47 patients in each group. The control group received no intervention treatment，the observation group was treated with modified Zhoufei decoction，continuous treatment of 6 courses，two groups were observed and compared the quality of life.Results: After treatment，the quality of life score (TMS)，daily living ability factor score (F1S)，social activity status factor score (F2S)，depression psychological symptom factor score (F3S)，anxiety psychological symptom factor score (F4S) of the 2 groups were significantly improved,Compared with before treatment (P＜0.05)，and the observation group improved obviously than the control group，the difference was statistically significant (P＜0.05). The 2 groups after treatment of clinical symptoms (cough，wheezing，shortness of breath，sputum) was significantly reduced，compared with before treatment (P＜0.05)，and the observation group decreased compared with the control group，the difference was statistically significant (P＜0.05). After treatment，2 groups of FVC (VCmax)，forced expiratory volume in 1 (FEV1)，a second volume ratio of FVC (FEV1/FVC)，maximal midexpiratory mean velocity (MMEF)，peak expiratory flow rate (PEF) significantly improved，compared with before treatment (P＜0.05)，and the observation group improved than the control group obviously，the difference was statistically significant (P＜0.05). During this treatment and observation period，no serious adverse reactions occurred in both groups，with no significant difference (P＞0.05).Conclusion :Modified Zhoufei decoction has a positive impact on the quality of life in patients with chronic obstructive pulmonary disease in stable phase，can improve the quality of life of patients，improve the clinical symptoms，delay the decline trend of lung function.

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更新日期/Last Update: 2019-01-07