[1]姜 超,王 婷,胡燕琪,等.基于中医症征积分探讨益气活血方调节微栓子对急性缺血性脑卒中患者生活质量的影响*[J].陕西中医,2020,(4):459-461,480.
　JIANG Chao,WANG Ting,HU Yanqi,et al.Clinical efficacy of Yiqi Huoxue granule for the life quality of stroke patients with embolism positive by the stroke scale of traditional Chinese medicine[J].,2020,(4):459-461,480.
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基于中医症征积分探讨益气活血方调节微栓子对急性缺血性脑卒中患者生活质量的影响*
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2020年4期
页码:
459-461,480
栏目:
临床研究
出版日期:
2020-04-05

文章信息/Info

Title:
Clinical efficacy of Yiqi Huoxue granule for the life quality of stroke patients with embolism positive by the stroke scale of traditional Chinese medicine
文章编号:
DOI:10.3969/j.issn.10007369.2020.04.016
作者:
姜 超1; 2; 王 婷3; 胡燕琪4; 李豪鹏2; 徐中菊5△; 屈小元6
1.西安医学院第二附属医院神经内三科(西安 710038); 2.兵器工业521医院神经内一科(西安 710065); 3.西安电子科技大学经济与管理学院(西安 710071); 4.上海健康医学院实践教学中心(上海 201318); 5.上海市光华中西医结合医院治未病科(上海 200052); 6.陕西省中医医院急诊科(西安 710003)
Author(s):
JIANG Chao; WANG Ting; HU Yanqi; et al.
The Third Department of Neurology,the Second Affiliated Hospital of Xi'an Medical University(Xi'an 710038)
关键词:
益气活血颗粒;  缺血性卒中;  中风;  中医症征积分量表;  微栓子;  影响
Keywords:
Yiqi Huoxue granule;  Ischemic stroke;  Stroke;  TCM syndrome subscale;  Microemboli;  Influence
分类号:
R255.2
文献标志码:
A
摘要:
目的:通过随机、对照的研究方法,运用中风中医症征积分量表客观地评价益气活血颗粒对急性缺血性卒中(AIS)并微栓子(MES)阳性的患者生活质量的影响。方法:将120例AIS患者分为益气活血颗粒试验组和安慰剂对照组,每组各60例。试验组在单纯西医常规治疗的基础上,给予益气活血颗粒联合西药为一体的中西医结合综合治疗方案; 对照组为西医常规治疗,疗程为14 d,客观评价中西医结合综合方案可明显缓解AIS患者中医症状的临床表征以及对患者个体日常生活能力改善的临床疗效。结果:益气活血颗粒在改善AIS患者中医症状积分及临床症状对日常生活影响程度积分方面明显优于对照组(P<0.05)。结论:益气活血颗粒能明显减少AIS患者颅内MES数目,有效改善患者的中医症征积分,并可能因此而改善患者的临床症状使其获益,此种中西医结合治疗AIS的方法值得应用。
Abstract:
Objective:To objectively evaluate clinical efficacy of Yiqi Huoxue granule for the life quality of patients with acute ischemic stroke(AIS)and microembolic signal(MES)by using the stroke scale of traditional Chinese medicine(TCM),under the randomized controlled study.Methods:120 cases of acute ischemic stroke patients were divided into Yiqi Huoxue granule(treatment group)and controll group,60 patients in each group.In the common conventional basic treatment,the treatment group was given Yiqi Huoxue granules,but the control group was only given placebo.After 2 weeks of treatment,the changes in the number of microemboli were observed and the clinical efficacy was evaluated using the NIHSS scale.Results:Treatment group in improving the scores of stroke symptoms of TCM and its influence on daily life of stroke patients were significantly better than controll group(P<0.05).Conclusion:Yiqi Huoxue granule in the stroke scale of TCM has good clinical efficacy.

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备注/Memo

备注/Memo:
*陕西省科技重点研发计划项目(2017SF-348)；陕西省卫生计生科研基金项目(2016D059)；上海市浦东新区科委基金创新资助项目(PKJ2015-Y47)；上海市科学技术委员会项目(19401970800)；上海市中医药事业发展三年行动计划(ZY(2018-2020)-ZWB-1001-CPJS21)；信立泰药业重点基础课题(2016XLT01)
更新日期/Last Update: 2020-04-13