[1]向亚玲,徐 婷.神应1号生发汤治疗血虚风燥型脂溢性脱发临床研究*[J].陕西中医,2020,(5):639-642.[doi:DOI:10.3969/j.issn.10007369.2020.05.024]
　XIANG Yaling,XU Ting..Clinical effect of No.1 Shenying Shengfa decoction in the treatment of sebrrheic alopecia blood-deficiency and wind-dryness type[J].,2020,(5):639-642.[doi:DOI:10.3969/j.issn.10007369.2020.05.024]
点击复制

神应1号生发汤治疗血虚风燥型脂溢性脱发临床研究*
分享到：

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2020年5期
页码:
639-642
栏目:
临床研究
出版日期:
2020-05-05

文章信息/Info

Title:
Clinical effect of No.1 Shenying Shengfa decoction in the treatment of sebrrheic alopecia blood-deficiency and wind-dryness type
作者:
向亚玲; 徐 婷
核工业416医院中医美容科(成都 610051)
Author(s):
XIANG Yaling; XU Ting.
Traditional Chinese Medicine Department of Aesthetics,Nuclear Industry 416 Hospital(Chengdu 610051)
关键词:
脂溢性脱发;  血虚风燥型;  神应1号生发汤;  血液流变学;  疗效;  中医证候
Keywords:
Seborrheic alopecia;  Blood-deficiency and wind-dryness type;  No.1 Shenying Shengfa decoction;  Hemorheology;  Curative effect;  TCM syndrome
分类号:
R589
DOI:
DOI:10.3969/j.issn.10007369.2020.05.024
文献标志码:
A
摘要:
目的:探究神应1号生发汤对脂溢性脱发(血虚风燥型)疗效、血液流变学的影响。方法:以103例脂溢性脱发(血虚风燥型)患者为对象,按医师建议及患者自愿原则分为治疗组(神应1号生发汤,n=52)及对照组(常规西药治疗,n=51),比较两组疗效、治疗前后中医证候积分、血液流变学指标及药物安全性。结果:治疗组总有效率明显高于对照组(P<0.05); 治疗前两组头发干枯、稀疏脱落、伴白屑、头皮瘙痒证候积分、全血黏度、血浆黏度、红细胞压积、血沉比较差异无统计学意义(P>0.05); 治疗后两组头发干枯、稀疏脱落、伴白屑、头皮瘙痒证候积分较治疗前明显降低,且治疗组明显低于对照组(P<0.05),与同组治疗前比较,两组全血黏度、血浆黏度、红细胞压积、血沉均明显降低,并且治疗后治疗组明显低于对照组(P<0.05),治疗组不良反应总发生率与对照组比较,差异无统计学意义(P>0.05)。结论:神应1号生发汤治疗脂溢性脱发(血虚风燥型)的疗效明显,可有效改善患者的中医证候及血液流变学。
Abstract:
Objective:To explore the effects of No.1 Shenying Shengfa decoction in the treatment of sebrrheic alopecia(blood-deficiency and wind-dryness type)and the influence on hemorheology.Methods:A total of 103 patients with sebrrheic alopecia of blood-deficiency and wind-dryness type who were diagnosed and treated were selected as the subjects.According to doctors' recommendations and the voluntary principle,the subjects were divided into the experimental group(treated with No.1 Shenying Shengfa decoction,n=52)and the control group(treated with conventional western medicine,n=51).The curative effect,TCM symptom scores before and after treatment,hemorheological indexes and drug safety were compared between two groups.Results:The total response rate in experimental group was significantly higher than that in control group(P<0.05).Before treatment,there were no significant differences in scores of sparse,shedding and dry hair,dandruff and scalp itching,whole blood viscosity,plasma viscosity,hematocrit or erythrocyte sedimentation rate between the two groups(P>0.05).After treatment,the above scores of both groups were significantly decreased,and the scores in experimental group were significantly lower than those in control group(P<0.05).After treatment,the whole blood viscosity,plasma viscosity,hematocrit and erythrocyte sedimentation rates in both groups were significantly decreased.Besides,the above indexes in experimental group were significantly lower than those in control group(P<0.05).There was no significant difference in the overall incidence rate of adverse reactions between the two groups(P>0.05).Conclusion:No.1 Shenying Shengfa decoction is markedly effective in the treatment of seborrheic alopecia(blood-deficiency and wind-dryness type).It can effectively improve TCM syndromes and hemorheology of patients.

参考文献/References:

[1] 陈亚洲,匡 琳,黄恩惠.祛脂生发液联合米诺地尔治疗脂溢性脱发的临床观察[J].湖南中医药大学学报,2017,37(11):1285-1287.
[2] 贾华魁,李琳婕.二至丸加味联合非那雄胺治疗脂溢性脱发的临床研究[J].现代中西医结合杂志,2019,28(24):2684-2686,2724.
[3] 杨玉峰,刘少芬,黄艳红,等.蒲公英在治疗脾虚湿热型脂溢性脱发中的临床疗效研究[J].河北中医药学报,2017,32(6):11-13.
[4] 程 权,傅华洲.傅华洲主任治疗斑秃经验简析[J].浙江中医药大学学报,2016,40(9):693-695.
[5] 国家中医药管理局.中医内科病证诊断疗效标准(六)[J].湖北中医杂志,2002,24(7):25-27.
[6] 国家中医药管理局.《中医病证诊断疗效标准》[M].南京:南京大学出版社,1995:125.
[7] 汤顺利,方 红.雄激素性秃发的发病机制[J].中华皮肤科杂志,2019,52(3):208-210.
[8] 罗 莎,陈颖颖,冯 放,等.杨顶权中西医结合治疗雄激素性秃发经验[J].北京中医药,2019,23(5):442-445.
[9] 余 其,曹 毅,何慧英,等.生发Ⅰ号胶囊联合米诺地尔酊溶液治疗男性脂溢性脱发42例[J].浙江中医杂志,2018,17(6):450.
[10] 付 宁,梁 红,贾格桃,等.西比灵联合地巴唑对血管神经性头痛患者血液流变学及血流动力学影响[J].陕西医学杂志,2017,46(8):1109-1110.
[11] 赵 婵,王锁杏.生发1号汤治疗脂溢性脱发的临床观察[J].陕西中医,2015,28(10):1388-1389.
[12] 蔡 云.依巴斯汀联合卡介苗素和胱氨酸治疗斑秃疗效观察[J].中国麻风皮肤病杂志,2011,27(1):72-73.
[13] 何 斌.祛湿生发汤治疗湿热内蕴型脂溢性脱发75例[J].四川中医,2013,32(4):116-117.
[14] 李 强,吴景东.养血通络生发汤治疗肝肾亏损型脂溢性脱发96例[J].河北中医,2009,31(1):104,124.
[15] 潘宪伟,赵余庆.侧柏叶和果实中黄酮类和萜类物质的现代药学研究进展[J].中草药,2012,43(8):1641-1646.

相似文献/References:

[1]高 然,李乃芳,崔 铖,等.加味除湿胃苓合剂治疗脂溢性脱发疗效及对患者微量元素、激素的影响[J].陕西中医,2021,(9):1250.[doi:DOI:10.3969/j.issn.1000-7369.2020.09.026]

备注/Memo

备注/Memo:
*四川省卫生和计划生育委员会科研课题(2015JM02146)
更新日期/Last Update: 2020-05-14