[1]黄英媛,宋振华△,徐焕杰,等.补阳还五汤联合梅花针叩刺治疗脑梗死偏瘫疗效研究*[J].陕西中医,2020,(6):815-818.[doi:DOI:10.3969/j.issn.10007369.2020.06.033]
 HUANG Yingyuan,SONG Zhenhua,XU Huanjie,et al.Clinical effect of Buyang Huanwu decoction combined with plum flower needle tapping on cerebral infarction hemiplegia[J].,2020,(6):815-818.[doi:DOI:10.3969/j.issn.10007369.2020.06.033]
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补阳还五汤联合梅花针叩刺治疗脑梗死偏瘫疗效研究*
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2020年6期
页码:
815-818
栏目:
针灸经络
出版日期:
2020-06-01

文章信息/Info

Title:
Clinical effect of Buyang Huanwu decoction combined with plum flower needle tapping on cerebral infarction hemiplegia
作者:
黄英媛1宋振华1△徐焕杰2刘春苗1
1.中南大学湘雅医学院附属海口医院(海口 570208); 2.中南大学湘雅医学院附属海口医院海港分院(海口 570311)
Author(s):
HUANG YingyuanSONG ZhenhuaXU Huanjieet al.
Central South University Xiangya School of Medicine Affiliated Haikou Hospital(Haikou 570208)
关键词:
脑梗死 偏瘫 补阳还五汤 梅花针叩刺 炎性因子
Keywords:
Cerebral infarction Hemiplegia Buyang Huanwu decoction Plum-blossom needle tapping Inflammatory cytokines
分类号:
R255.2
DOI:
DOI:10.3969/j.issn.10007369.2020.06.033
文献标志码:
A
摘要:
目的:探讨补阳还五汤联合梅花针叩刺治疗脑梗死偏瘫的临床效果。方法:选取106例脑梗死偏瘫患者,按随机数字表法分为对照组和观察组,每组53例,对照组给以梅花针叩刺及常规手法,观察组在对照组的基础上给以补阳还五汤。比较两组治疗效果。结果:治疗1个月后,两组神经功能缺损情况均改善、FIM和BI评分均提高,且观察组较对照组明显好转(P<0.05)。经两个疗程,两组患者血清中的炎性因子IL-8 、TNF-α 、hs-CRP水平较治疗前均明显降低,且观察组炎症情况较对照组明显减轻( P<0.05)。两组患者的CTRP9、SES指标均有所提高,且观察组明显高于对照组(P<0.05)。观察组临床疗效总有效率94.34%,明显高于对照组75.47%。结论:补阳还五汤联合梅花针叩刺治疗脑梗死偏瘫具有良好的临床疗效,补阳还五汤能够促进患者神经功能缺损的好转,降低患者血清中的炎症因子并提高CTRP9、SES指标的水平,改善了患者的生活独立性,取得了较理想的临床治疗效果。
Abstract:
Objective:To investigate the clinical effect of Buyang Huanwu decoction combined with plum flower needle tapping in the treatment of cerebral infarction hemiplegia.Methods:106 patients with cerebral infarction and hemiplegia were selected and divided into control group and observation group according to the random number table method,with 53 cases in each group.Treatment outcomes were compared.Results:After one month of treatment,the neurological deficits of the two groups were improved,and the FIM and BI scores were increased.The neurological function of observation group was significantly better than the control group(P<0.05).After two courses of treatment,the serum levels of inflammatory factors IL-8,TNF-α and hs-CRP in the two groups were significantly lower than those before treatment,and the inflammation in the observation group was significantly lower than that in the control group(P<0.05).The CTRP9 and SES indexes of the two groups were improved,and that of the observation group was significantly higher than the control group(P<0.05).The total effective rate in the observation group(94.34%)was significantly higher than that in the control group(75.47%).Conclusion:Buyang Huanwu decoction combined tap thorn plum needle treatment of cerebral infarction hemiplegia has good clinical curative effect and Buyang Huanwu decoction can promote patients with nerve function defect,reduce the inflammation in the patients with serum factor and improve the level of CTRP9,SES indicators,improve the patients life independence,better clinical therapeutic effect.

参考文献/References:

[1] Yang L,Xin Z,Hui S,et al.Urban-rural differences in risk factors for ischemic stroke in northern China[J].Medicine,2019,98(21):15782.
[2] 贺龙梅,王 禺,王 凌,等.血清同型半胱氨酸、血浆纤维蛋白原与尿微量白蛋白联合检测预测脑梗死风险评估临床研究[J].陕西医学杂志,2019,48(7):903-905.
[3] 胡 平,张裕民.两种内固定术在老年脑卒中偏瘫侧股骨粗隆间骨折治疗中的运用效果观察[J].陕西医学杂志,2019,48(3):355-357.
[4] 路永坤,杨海燕,刘向哲,等.补阳还五汤佐治超早期脑梗死患者对静脉溶栓后出血性转化的影响[J].中国中药杂志,2019,44(8):1696-1703.
[5] 马 琳,李学智,姚太万,等.不同针灸疗法对老年雄性大鼠下丘脑-睾丸中生殖激素调控系统相关基因表达的影响[J].针刺研究,2019,44(3):200-204.
[6] 侯晓强,杨 娜,李壬子.针刺联合豁痰息痉汤对脑梗死合并癫痫患者神经功能的影响评价[J].中华中医药学刊,2018,36(5):1245-1247.
[7] Uhlen M,Zhang C,Lee S,et al.A pathology atlas of the human cancer transcriptome[J].Science,2017,357(6352):1126.
[8] 周军怀.川芎嗪注射液联合补阳还五汤治疗急性脑梗死的临床观察[J].陕西中医,2016,37(8):1005-1006.
[9] 杨文海,宁显忠,赵德福,等.脑梗死患者血清五聚素3、甲壳质酶蛋白40和白细胞分化抗原36表达及检测临床意义[J].陕西医学杂志,2019,48(3):301-303.
[10] 吕立峰,亓爱芹,李秀芹.温脾通络开窍汤联合丁苯酞治疗老年血管性痴呆的疗效及对高血浆同型半胱氨酸、炎症因子的影响[J].中华中医药学刊,2018,36(5):1262-1265.
[11] 钟 灿,何红晨,黄双霜,等.虚拟现实技术对脑卒中偏瘫患者上肢运动功能恢复的影响的Meta分析[J].中华物理医学与康复杂志,2019,41(6):463-468.
[12] 樊启猛.基于分子对接技术的补阳还五汤成分与缺血性脑卒中靶点的相互作用研究[J].中草药,2019,50(17):4200-4208.
[13] 卢志刚,吕晓强,刘 芸,等.急性脑梗死患者信号传导及转录激活子-4、6与神经功能缺损以及梗死体积的相关性研究[J].中华实验外科杂志,2015,32(9):2110-2112.
[14] Dong WL,Xiao RT.Clinical significance of Lp(a)and hs-CRP detection in ACI[J].China Modern Medicine,2017,24(4):58-60.
[15] 戴建立,李 榕,刘海婷,等.脑梗死患者血清CTRP9水平的改变及其临床意义[J].中华内科杂志,2019,58(6):449 - 452.
[16] 余 凌,王玉娇.针灸联合早期康复对急性脑梗死患者神经功能及血清SES、hs-CRP水平的影响[J].针灸临床杂志,2017,33(3):12-15.
[17] 王志旺,程小丽,任 远,等.当归对阴虚哮喘小鼠气道MUC5AC及相关炎症因子表达的影响[J].中国免疫学杂志,2016,32(1):42-45.
[18] 杨 铭,林海燕,傅志泉.黄芪注射液联合血塞通治疗气虚血瘀型急性脑梗死临床疗效观察[J].中华中医药学刊,2017,35(5):23-25.

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备注/Memo

备注/Memo:
*海南省卫生计生行业科研项目(117)
更新日期/Last Update: 2020-06-09