[1]朱凤娣,田 颖,钟剑飞,等.康妇炎胶囊治疗湿热蕴结型盆腔炎性疾病后遗症及对患者IL-2、TNF-α的影响研究*[J].陕西中医,2020,(8):1095.[doi:DOI:10.3969/j.issn.1000-7369.2020.08.021]
　ZHU Fengdi,TIAN Ying,ZHONG Jianfei,et al.Effect of Kangfuyan capsule on IL-2,TNF-α and its curative effect on patients with sequelae of damp-heat accumulation-type pelvic inflammatory disease[J].,2020,(8):1095.[doi:DOI:10.3969/j.issn.1000-7369.2020.08.021]
点击复制

康妇炎胶囊治疗湿热蕴结型盆腔炎性疾病后遗症及对患者IL-2、TNF-α的影响研究*
分享到：

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2020年8期
页码:
1095
栏目:
临床研究
出版日期:
2020-08-05

文章信息/Info

Title:
Effect of Kangfuyan capsule on IL-2,TNF-α and its curative effect on patients with sequelae of damp-heat accumulation-type pelvic inflammatory disease
作者:
朱凤娣1; 田 颖2; 钟剑飞1; 房玉洁1; 刘 鑫1
1.鞍钢集团总医院(鞍山 114000); 2.长春市妇产医院(长春 130000)
Author(s):
ZHU Fengdi; TIAN Ying; ZHONG Jianfei; et al.
Ansteel Group General Hospital(Anshan 114000)
关键词:
湿热蕴结型;  盆腔炎性疾病后遗症;  康妇炎胶囊;  白介素2;  肿瘤坏死因子
Keywords:
Damp-heat accumulation type;  Sequelae of pelvic Inflammatory disease;  Kangfuyan capsule;  IL-2;  TNF-α
分类号:
R711.33
DOI:
DOI:10.3969/j.issn.1000-7369.2020.08.021
文献标志码:
A
摘要:
目的:探讨康妇炎胶囊对湿热蕴结型盆腔炎性疾病后遗症患者的IL-2、TNF-α及疗效影响。方法:选取96例湿热蕴结型盆腔炎性疾病后遗症患者,随机分为两组,对照组采用抗生素治疗,观察组在对照组基础上采用康妇炎胶囊治疗,比较两组患者治疗前后的中医证候积分、疼痛程度、白介素2(IL-2)、肿瘤坏死因子(TNF-α)及停药6个月的复发情况。结果:观察组治疗后中医证候积分、局部证候积分、总证候积分、下腹部疼痛、腰骶部酸胀疼痛、经期腹痛程度评分及TNF-α水平均较对照组明显降低(P<0.05); 观察组治疗后总有效率及IL-2水平高于对照组(P<0.05); 观察组患者治疗结束后6个月复发率低于对照组(P<0.05)。结论:康妇炎胶囊用于湿热蕴结型盆腔炎性疾病后遗症患者能够有效改善中医证候,降低疼痛程度及改善机体免疫水平。
Abstract:
Objective:To investigate the effects of Kangfuyan capsule on IL-2,TNF-α and its curative effect in patients with sequelae of dampness and heat accumulation in pelvic inflammatory disease.Methods:96 patients with sequela of pelvic inflammatory disease with damp heat accumulation.The control group was treated with antibiotics,and the observation group was treated with Kangfuyan capsule on the basis of the control group.Results:After treatment,the scores of symptoms of traditional Chinese medicine,local syndromes,total syndromes,lower abdominal pain,lumbosacral pain,abdominal pain and TNF-α were significantly lower than those of control group(P<0.05).The total effective rate and IL-2 level of the observation group after treatment was significantly higher than that of the control group(P<0.05).The recurrence rate of the patients in the observation group after the end of treatment,which was significantly lower than that in the control group(P<0.05).Conclusion:Kangfuyan capsule can effectively improve the syndrome of traditional Chinese medicine,reduce the degree of pain and improve the immune level of the body,reduce the inflammatory response.

参考文献/References:

[1] 中华医学会妇产科学分会感染性疾病协作组.盆腔炎症性疾病诊治规范(2019修订版)[J].中华妇产科杂志,2019,54(7):433-437.
[2] 张博雯,张铁英,涂飞霞.活血化瘀法治疗盆腔炎性疾病后遗症临床观察[J].新中医,2017,49(4):92-94.
[3] Long B,April MD.What antibiotic regimen is most efficacious in treating pelvic inflammatory disease?[J].Annals of Emergency Medicine,2017,70(6):840.
[4] 刘鹤玢,韩延华.韩氏妇炎汤联合中药保留灌肠治疗湿热蕴结型盆腔炎性疾病后遗症临床观察[J].新中医,2017,49(9):85-87.
[5] 谢 凡,宋 英,黄永亮.中西医治疗盆腔炎性疾病的临床用药进展[J].中国药房,2017,28(30):4312-4315.
[6] 马 堃,罗颂平,李 敏,等.中医药防治盆腔炎性疾病优势与证据研究进展[J].中国中药杂志,2017,42(8):1449-1454.
[7] 刘元姣.新编妇产科疾病诊疗学[M].北京:人民卫生出版社,2002:52-53.
[8] 国家中医药管理局.中药新药临床研究指导原则(试行)[M].北京:中国医药科技出版社,2002:124-125.
[9] 李晓梅.替硝唑联合盐酸左氧氟沙星治疗盆腔炎性疾病的应用价值[J].世界临床医学,2019,13(4):162-163.
[10] 刘彤鸥,王加谋,王师菡.化瘀固本方对慢性盆腔炎大鼠相关细胞因子及血液流变学的影响[J].中药材,2016,39(1):170-173.
[11] 李 崧,刘桂荣.国医大师张志远妇科验案四则 [J].中华中医药杂志,2018,33(7):170-172.
[12] 黄发婷,梁 漫,孙志圣.盆腔灌注联合TDP治疗慢性盆腔炎临床疗效研究[J].陕西医学杂志,2019,48(2):205-207.
[13] 陈 瑶,姜晓春,杨鉴冰,等.盆炎消联合盆腔灌注治疗湿热瘀结型盆腔炎性疾病后遗症临床研究 [J].陕西中医药大学学报,2019,42(3):121-124.
[14] 龚 巍,万 莉,刘 娜.清热理血汤联合康妇消炎栓治疗老年急性盆腔炎的临床研究[J].中药药理与临床,2016,17(1):202-204.
[15] 要 静,王利平,张红霞.清热理血汤治疗盆腔炎后遗症疗效及对患者血清粒-巨噬细胞集落刺激因子白细胞介素-2血流变学的影响 [J].陕西中医,2019,40(6):746-748.

相似文献/References:

[1]边卓琼,张 薇,姜 敏△,等.痹症1号联合醋氯芬酸片治疗湿热蕴结型急性痛风性关节炎疗效研究*[J].陕西中医,2019,(10):1415.

备注/Memo

备注/Memo:
*辽宁省科学技术基金资助课题(2018225003)
更新日期/Last Update: 2020-08-10