[1]张珊珊,贺 君,林彦廷,等.“胃不和则卧不安”治疗失眠机制探讨[J].陕西中医,2021,(5):625-628.[doi:DOI:10.3969/j.issn.1000-7369.2020.05.020]
　ZHANG Shanshan,HE Jun,LIN Yanting,et al.A study of the mechanism of insomnia treatment in “Stomach disorder causes restless sleep”[J].,2021,(5):625-628.[doi:DOI:10.3969/j.issn.1000-7369.2020.05.020]
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“胃不和则卧不安”治疗失眠机制探讨
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2021年5期
页码:
625-628
栏目:
学术探讨
出版日期:
2021-05-05

文章信息/Info

Title:
A study of the mechanism of insomnia treatment in “Stomach disorder causes restless sleep”
作者:
张珊珊1; 贺 君2; 林彦廷1; 江钢辉2
(1.广州中医药大学针灸康复临床医学院,广东 广州 510405; 2.广州中医药大学第一附属医院,广东 广州 510405)
Author(s):
ZHANG Shanshan; HE Jun; LIN Yanting; JIANG Ganghui
(Clinical College of Acupuncture and Rehabilitation,Guangzhou University of Chinese Medicine,Guangzhou 510405,China)
关键词:
胃不和则卧不安;  失眠;  足阳明胃经;  脑肠轴;  脑肠肽;  短链脂肪酸
Keywords:
Stomach upset;  Restless sleep;  Insomnia;  Foot-yangming stomach meridian;  Brain-gut axis;  Brain-gut peptide;  Short-chain fatty acid
分类号:
R 256.23
DOI:
DOI:10.3969/j.issn.1000-7369.2020.05.020
文献标志码:
A
摘要:
“胃不和则卧不安”最早载于《素问·逆调论》,该理论为失眠症的治疗提供了重要的理论指导,然医家们对其解读却不尽相同。通过研读古代文献和现代研究,深入探讨其原理。“胃不和”指足阳明胃经经气不顺,逆而上行; 而“卧不安”,既有医家认为是指喘而不得卧,亦有医家认为指睡眠不安,而后者更令人信服; 中医病机方面,主要从气血失调、实邪壅滞、肝胃不和、足阳明胃经逆乱等方面进行论述; 西医原理方面,主要探索了脑肠轴系统中脑肠肽、肠道菌群代谢产物短链脂肪酸影响睡眠的机制。通过探讨何为“胃不和” “卧不安”以及“胃不和则卧不安”的理论机制,以期为临床治疗失眠拓展诊疗思路,更好地用经典理论指导临床运用。
Abstract:
“Stomach disorder causes restless sleep” was first put forward in “Nidiaolun” in “Suwen” in Huangdi Neijing.This theory provides important theoretical guidance for the treatment of insomnia.However,medical scientists have different interpretations of it.Through studying ancient literature and modern research,this article deeply explores its principles.In terms of literal meaning,“stomach disorder” means that the Qi in the stomach meridian of Foot Yangming does not go smoothly,but goes up backwards; some doctors think that “restless sleep” means the inability to lie down because of panting,and others think it means sleep disorder,which is more convincing.In terms of pathogenesis of traditional Chinese medicine,this essay mainly discusses the disorder of Qi and blood,the stasis of pathogenic factors,liver-stomach disharmony,and the inverse disorder of the stomach meridian of Foot Yangming.In terms of the principles of western medicine,it mainly explores the mechanism of brain-gut peptide and short-chain fatty acids,which affects sleep.Through exploring the true meaning of “stomach disorder” and “restless sleep”,and the theoretical mechanism of the theory of “stomach disorder causes restless sleep”,the essay aims to explore the approaches of the diagnosis and clinical treatment of insomnia,and better put classic theories into clinical application.

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备注/Memo

备注/Memo:
基金项目:广东省自然科学基金资助项目(2018A030313270); 杨文辉广东省名中医传承工作室项目(粤中医办函[2019]5号)
更新日期/Last Update: 2021-05-10