[1]陈玮黎,薛晓红,李思雨,等.扶正祛邪方对三阴性乳腺癌术后复发转移及免疫功能的影响[J].陕西中医,2021,(6):739-742.[doi:DOI:10.3969/j.issn.1000-7369.2020.06.015]
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扶正祛邪方对三阴性乳腺癌术后复发转移及免疫功能的影响
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2021年6期
页码:
739-742
栏目:
临床研究
出版日期:
2021-06-05

文章信息/Info

作者:
陈玮黎薛晓红李思雨张馨月沙珊焱陆 清
(上海中医药大学附属岳阳中西医结合医院,上海 200437)
关键词:
三阴性乳腺癌 扶正祛邪方 中医证候 外周T淋巴细胞 复发转移
分类号:
R 737.9
DOI:
DOI:10.3969/j.issn.1000-7369.2020.06.015
文献标志码:
A
摘要:
目的:观察三阴性乳腺癌(TNBC)术后在西医规范治疗的基础上联合扶正祛邪方对患者生存情况、免疫功能的影响。方法:将151例行手术治疗的TNBC患者按照有无服用扶正祛邪方分为观察组、对照组。比较两组患者生存及复发情况,以及治疗6个月后患者的免疫功能、中医证候积分以及不良反应。结果:观察组复发转移率及病死率低于对照组,差异有统计学意义(均P<0.05)。观察组总生存期(OS)和无病生存期(DFS)高于对照组,差异有统计学意义(均P<0.05)。治疗6个月后,观察组烦躁易怒、倦怠乏力、胁肋胀痛、口苦的中医证候积分低于对照组(均P<0.05)。观察组CD4+、CD4+/CD8+高于治疗前,且观察组高于对照组,差异有统计学意义(均P<0.05)。两组患者总不良反应发生率比较,差异无统计学意义(P>0.05)。结论:TNBC术后采用扶正祛邪方治疗,可降低患者复发转移率,改善免疫功能,提高生活质量。

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备注/Memo

备注/Memo:
基金项目:上海市科学技术委员会科技支撑项目(14401933200); 上海中医药大学课题(30304113626,2015YSN44)
更新日期/Last Update: 2021-06-09