[1]蒋 旭,胡 勇,程松苗,等.桃红四物汤合五苓散加减治疗对前交叉韧带重建术后早期膝关节肿胀、疼痛及关节功能康复的影响[J].陕西中医,2021,(10):1416-1419.[doi:DOI:10.3969/j.issn.1000-7369.2020.10.023]
　JIANG Xu,HU Yong,CHENG Songmiao,et al.Effect of modified Taohong Siwu decoction combined with Wuling powder on early joint knee swelling,pain and joint function rehabilitation after anterior cruciate ligament reconstruction[J].,2021,(10):1416-1419.[doi:DOI:10.3969/j.issn.1000-7369.2020.10.023]
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桃红四物汤合五苓散加减治疗对前交叉韧带重建术后早期膝关节肿胀、疼痛及关节功能康复的影响
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2021年10期
页码:
1416-1419
栏目:
临床研究
出版日期:
2021-10-05

文章信息/Info

Title:
Effect of modified Taohong Siwu decoction combined with Wuling powder on early joint knee swelling,pain and joint function rehabilitation after anterior cruciate ligament reconstruction
作者:
蒋 旭; 胡 勇; 程松苗; 高 志; 林 瓒
(四川省骨科医院膝关节运动损伤科,四川 成都 610041)
Author(s):
JIANG Xu; HU Yong; CHENG Songmiao; GAO Zhi; LIN Zan
(Department of Knee Joint Sports Injury,Sichuan Orthopedic Hospital,Chengdu 610041,China)
关键词:
膝关节肿胀;  关节疼痛;  前交叉韧带重建术;  桃红四物汤;  五苓散;  关节功能
Keywords:
Joint knee swelling;  Joint pain;  Anterior cruciate ligament reconstruction;  Taohong Siwu decoction;  Wuling powder;  Joint function
分类号:
R 687.42
DOI:
DOI:10.3969/j.issn.1000-7369.2020.10.023
文献标志码:
A
摘要:
目的:探讨桃红四物汤合五苓散加减治疗对前交叉韧带(ACL)重建术后早期膝关节肿胀、疼痛及关节功能康复的影响。方法:选取98例ACL重建术后患者为对象,采用随机数字表法分为对照组(n=49)和观察组(n=49),对照组给予常规康复治疗,观察组在对照组基础上给予桃红四物汤合五苓散加减治疗,比较两组临床疗效、肿胀程度、肌肉萎缩程度、膝关节活动度、疼痛程度(VAS)评分、膝关节功能(Lysholm)评分、炎症因子[白介素-6(IL-6)、白介素-8(IL-8)、肿瘤坏死因子-α(TNF-α)]及免疫功能。结果:观察组治疗有效率高于对照组(91.84%与75.51%)(P<0.05); 治疗后两组肿胀程度、肌肉萎缩程度、VAS评分和IL-6、IL-8、TNF-α、CD8+水平均降低,膝关节活动度、Lysholm评分和CD3+、CD4+、CD4+/CD8+均升高(P<0.05),且观察组肿胀程度、肌肉萎缩程度、VAS评分和IL-6、IL-8、TNF-α、CD8+水平均显著低于对照组,膝关节活动度、Lysholm评分和CD3+、CD4+、CD4+/CD8+水平均显著高于对照组(P<0.05)。结论:桃红四物汤合五苓散加减治疗可改善ACL重建术后早期膝关节肿胀、疼痛程度及关节活动度,降低炎症因子水平,提高免疫功能,促进膝关节功能康复。
Abstract:
Objective:To discuss the effect of modified Taohong Siwu decoction combined with Wuling powder on early joint knee swelling,pain and joint function rehabilitation after anterior cruciate ligament(ACL)reconstruction.Methods:A total of 98 patients after ACL reconstruction were selected as subjects.They were divided into control group(n=49)and observation group(n=49)by random number method.The control group was given routine rehabilitation treatment.On this basis,the observation group was treated with modified Taohong Siwu decoction and Wuling powder.The clinical effects,swelling degree,muscle atrophy degree,knee joint activity,pain(VAS)scores,knee function(Lysholm)scores,inflammatory factors [Interleukin-6(IL-6),Interleukin-8(IL-8),Tumor necrosis factor-α(TNF-α)] and immune function in the two groups were compared.Results:The effective rate of treatment in the observation group was higher than that in the control group(91.84% vs.75.51%)(P<0.05).After treatment,the swelling degree,muscle atrophy degree,VAS scores and levels of IL-6,IL-8,TNF-α and CD8+ were reduced,knee joint activity,Lysholm scores,CD3+,CD4+ and CD4+/CD8+ were increased in the two groups(P<0.05).Besides,the swelling degree,muscle atrophy degree,VAS scores and levels of IL-6,IL-8,TNF-α and CD8+ in the observation group were significantly lower than those in the control group,knee joint activity,Lysholm scores,CD3+,CD4+ and CD4+/CD8+ were significantly higher than those in the control group(P<0.05).Conclusion:Treatment with modified Taohong Siwu decoction combined with Wuling powder can improve early joint knee swelling,pain and joint activity after ACL reconstruction while lowering the levels of inflammatory factors,improving immune function,and promoting knee function rehabilitation.

参考文献/References:

[1] 陈 军,鄂 刚,马震胜,等.膝关节前交叉韧带重建术后恢复不良患者应用复元活血汤对临床效果、膝关节疼痛和膝关节功能的影响[J].临床误诊误治,2020,33(3):68-72.
[2] 宋 楹,刘二龙.关节镜与传统切开手术治疗胫骨平台骨折合并前交叉韧带撕脱疗效对比研究[J].陕西医学杂志,2020,49(2):169-172.
[3] 喻 刚,吴威甫,周 燕,等.关节镜下自体腘绳肌和同种异体肌腱在重建前交叉韧带中的应用研究[J].陕西医学杂志,2020,49(3):309-312.
[4] 丁罗宾,赵 佳,关 健,等.电针对膝关节前交叉韧带重建术后膝关节运动功能康复的影响[J].中国针灸,2020,40(2):142-146.
[5] 李嘉祥,黄中强.中药内服外用对关节镜下膝前交叉韧带重建术后早期康复的影响[J].长春中医药大学学报,2017,33(2):125-128.
[6] 彭 俊,彭清华,吴权龙,等.活血化瘀利水明目法治疗外伤性前房积血继发性青光眼临床观察[J].辽宁中医杂志,2010,52(7):1293-1294.
[7] 胥少汀,葛宝丰,徐印坎.实用骨科学:全2册[M].北京:人民军医出版社,2012:117-119.
[8] 李国锐.中医病证诊断疗效标准[M].南京:南京大学出版社,1995:274-276.
[9] 冯兴龙,王 涵,冯 麟,等.全凭静脉麻醉联合超声引导下腹横肌平面阻滞在腹腔镜胃肠道手术中的临床研究[J].重庆医科大学学报,2018,43(1):56-59.
[10] 向珊珊,傅 明,张志奇,等.关节镜下自体或同种异体肌腱移植修复急性和陈旧性前交叉韧带损伤:重建效果评价[J].中国组织工程研究,2018,22(26):4174-4178.
[11] 樊继康,盖引莉,华 睿,等.中医配合锻炼在关节镜前交叉韧带重建术后的应用[J].中国中西医结合外科杂志,2019,25(1):5-10.
[12] 张占磊,斯 焱,马 邹,等.电针联合功能锻炼对KOA患者TKA术后疼痛及早期功能恢复的作用[J].四川中医,2020,38(11):197-200.
[13] 杨 尚,夏 洁.加味桃红四物汤治疗药物流产后出血疗效及对性激素水平影响研究[J].陕西中医,2018,39(3):351-353.
[14] 陈海波,郑志辉,林淑贞,等.桃红四物汤联合中药熏洗对Schatzker Ⅴ型胫骨平台骨折内固定术后患者愈合情况及炎症因子的影响[J].中国药师,2019,33(8):1461-1464.
[15] 何浩强,王 阶.五苓散加减方治疗慢性心力衰竭的研究进展[J].世界中西医结合杂志,2017,12(4):151-154.
[16] 肖 丽,王增玲.加味五苓散联合西药对急性肾小球肾炎患者Cys-C、UREA、Scr的影响[J].四川中医,2019,37(9):119-121.
[17] 邓 旭,冯松杰.连朴饮合五苓散治疗肾系疾病湿热证验案3则[J].江苏中医药,2018,50(4):55-57.
[18] 林晓绚,郭绍举.五苓散加减配合个体化饮食对腹泻型肠易激综合征的疗效分析[J].中国中西医结合消化杂志,2020,28(11):75-78.
[19] 钱雪丰,刘 拴,张明勇,等.桃红四物汤合五苓散内服外敷对膝关节半月板损伤术后功能康复的影响[J].现代中西医结合杂志,2017,14(7):726-728.
[20] 史开宇,赵其纯.兔自体BMSC移植修复前交叉韧带损伤效果及对血清u-PA、TGF-β、IL-1、IL-4水平的影响[J].山东医药,2018,58(42):36-39.

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备注/Memo

备注/Memo:
基金项目:四川省卫生和计划生育委员会科研课题(16PJ387)
更新日期/Last Update: 2021-10-09