[1]张斐雪,郑书林,张锡萍,等.针灸联合注射用鼠神经生长因子对脑卒中患者认知水平及神经功能的影响[J].陕西中医,2021,(10):1462-1465.[doi:DOI:10.3969/j.issn.1000-7369.2020.10.037]
　ZHANG Feixue,ZHENG Shulin,ZHANG Xiping,et al.Effect of acupuncture combined with mouse nerve growth factor for injection on cognitive level and neurological function of stroke patients[J].,2021,(10):1462-1465.[doi:DOI:10.3969/j.issn.1000-7369.2020.10.037]
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针灸联合注射用鼠神经生长因子对脑卒中患者认知水平及神经功能的影响
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2021年10期
页码:
1462-1465
栏目:
针灸经络
出版日期:
2021-10-05

文章信息/Info

Title:
Effect of acupuncture combined with mouse nerve growth factor for injection on cognitive level and neurological function of stroke patients
作者:
张斐雪1; 郑书林2; 张锡萍1; 蹇 睿1; 杨 敏1; 段小东1; 陈利莎3
(1.西南医科大学附属医院,四川 泸州 646000; 2.成都市第一人民医院康复科,四川 成都 610000; 3.西南医科大学附属中医医院针灸康复科,四川 泸州 646000)
Author(s):
ZHANG Feixue; ZHENG Shulin; ZHANG Xiping; JIAN Rui; YANG Min; DUAN Xiaodong; CHEN Lisha
(Affiliated Hospital of Southwest Medical University,Luzhou 646000,China)
关键词:
脑卒中;  针灸;  认知水平;  神经功能;  生活质量;  不良反应
Keywords:
Stroke;  Acupuncture;  Cognitive level;  Neurological function;  Quality of life;  Adverse reaction
分类号:
R 743.3
DOI:
DOI:10.3969/j.issn.1000-7369.2020.10.037
文献标志码:
A
摘要:
目的:探究针灸联合注射用鼠神经生长因子对脑卒中患者认知水平及神经功能的影响。方法:选取脑卒中患者132例为研究对象,随机分为对照组(n=66)和观察组(n=66),对照组给予常规治疗联合注射用鼠神经生长因子,观察组在对照组的基础上给予针灸,比较两组临床疗效、认知水平[简易精神状态检查量表(MMSE)和蒙特利尔认知评估量表(MoCA)]、中医症候积分、神经功能[美国国立卫生研究院卒中量表(NIHSS)]、生活质量[36条目简明健康量表(SF-36)]及不良反应。结果:观察组总有效率明显高于对照组(89.39% 与 75.76%,P<0.05); 与对照组比较,观察组治疗后MMSE评分和MoCA评分明显较高(P<0.05),中医症候积分和NIHSS评分明显较低(P<0.05),SF-36各维度评分明显较高(P<0.05); 观察组和对照组不良反应总发生率比较无统计学差异(7.58% 与 4.55%,P>0.05)。结论:针对脑卒中患者,在常规治疗基础上给予针灸联合注射用鼠神经生长因子具有较好的临床疗效,可减少中医症候积分,改善患者认知水平和神经功能,提升患者生活质量,安全性较好。
Abstract:
Objective:To explore the effect of acupuncture combined with mouse nerve growth factor for injection on cognitive level and neurological function of stroke patients.Methods:132 patients with stroke were randomly divided into control group(n=66)and observation group(n=66).Clinical efficacy,cognitive level(MMSE and MoCA),TCM symptom score,neurological function(NIHSS),quality of life(SF-36)and adverse reactions were compared between the two groups.Results:The total effective rate in the observation group was significantly higher than that in the control group(89.39% vs 75.76%,P<0.05).After treatment,MMSE score and MoCA score in observation group were significantly higher than those in control group(P<0.05),TCM symptom score and NIHSS score were significantly lower than those in control group(P<0.05),and SF-36 scores were significantly higher than those in control group(P<0.05).There was no difference in the total incidence of adverse reactions between the observation group and the control group(7.58% vs 4.55%,P>0.05).Conclusion:For stroke patients,acupuncture combined with injection of mouse nerve growth factor on the basis of routine treatment has good clinical efficacy,which can reduce TCM symptom scores,improve patients' cognitive level and neurological function,and improve patients' quality of life,with good safety.

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备注/Memo

备注/Memo:
基金项目:四川省卫生健康委员会科研课题(20PJ137)
更新日期/Last Update: 2021-10-09