[1]姜 锐,彭福梅,徐珊珊,等.养阴利咽汤联合针刺治疗慢性咽炎及对患者临床症状、炎性因子和免疫功能的影响[J].陕西中医,2022,(2):257-260.[doi:DOI:10.3969/j.issn.1000-7369.2022.02.028]
　JIANG Rui,PENG Fumei,XU Shanshan,et al.Effect of Yangyin Liyan decoction combined with acupuncture on clinical symptoms,inflammatory factors and immune function of patients with chronic pharyngitis[J].,2022,(2):257-260.[doi:DOI:10.3969/j.issn.1000-7369.2022.02.028]
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养阴利咽汤联合针刺治疗慢性咽炎及对患者临床症状、炎性因子和免疫功能的影响
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2022年2期
页码:
257-260
栏目:
针灸经络
出版日期:
2022-02-05

文章信息/Info

Title:
Effect of Yangyin Liyan decoction combined with acupuncture on clinical symptoms,inflammatory factors and immune function of patients with chronic pharyngitis
作者:
姜 锐1; 彭福梅1; 徐珊珊1; 陈 艳1; 黄雪芹2
(1.湖北省中医院,湖北 武汉 430061; 2.黄石市中心医院,湖北 黄石 435000)
Author(s):
JIANG Rui; PENG Fumei; XU Shanshan; CHEN Yan; HUANG Xueqin
(Hubei Provincial Hospital of Traditional Chinese Medicine,Wuhan 430061,China)
关键词:
慢性咽炎;  养阴利咽汤;  针刺疗法;  炎性因子;  免疫功能
Keywords:
Chronic pharyngitis;  Yangyin Liyan decoction;  Acupuncture therapy;  Inflammatory factors;  Immunologic function
分类号:
R 766.14
DOI:
DOI:10.3969/j.issn.1000-7369.2022.02.028
文献标志码:
A
摘要:
目的:探讨养阴利咽汤联合针刺对慢性咽炎患者临床症状、炎性因子及免疫功能的影响。方法:选取耳鼻咽喉门诊收治的180例慢性咽炎患者,随机分为观察组和对照组各90例,两组患者均给予常规西医治疗,在此基础上同时为观察组采用中医方剂养阴利咽汤联合针刺疗法治疗。比较两组临床症状改善情况、临床疗效、血清炎性因子水平变化及免疫功能改善情况。结果:治疗后,观察组临床总有效率、外周血CD3+、CD4+、CD4+/CD8+水平均高于对照组(P<0.05),白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、超敏C-反应蛋白(hs-CRP)、B细胞数、中医症状评分均低于对照组(P<0.05); 两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:肺肾阴虚型慢性咽炎患者采用养阴利咽汤联合针刺疗法,能显著改善患者临床症状,有良好的抗炎效果,还可提升临床疗效及患者免疫功能。
Abstract:
Objective:To explore the effect of Yangyin Liyan decoction combined with acupuncture on clinical symptoms,inflammatory factors and immune function of patients with chronic pharyngitis.Methods:180 patients with chronic pharyngitis were selected and randomly divided into observation group and comparison group,90 cases in each group.Both groups were given routine western medicine treatment,and on the basis of this,the observation group was treated with Yangyin Liyan decoction combined with acupuncture therapy.The improvement of clinical symptoms,clinical efficacy,changes of serum inflammatory factors and improvement of immune function were compared between the two groups.Results:After treatment,the total clinical response rate,the levels of CD3+,CD4+ and CD4+/CD8+ in peripheral blood of the observation group were higher than those of the comparison group(P<0.05),IL-6,TNF-α,hs-CRP,B cell number and TCM symptom score were lower than those of the comparison group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Yangyin Liyan decoction combined with acupuncture therapy can significantly improve the clinical symptoms of patients with chronic pharyngitis with lung and kidney-yin deficiency,and it has good anti-inflammatory effect.It can also improve the clinical efficacy and immune function of patients,which is worthy of popularization and application.

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备注/Memo

备注/Memo:
基金项目:湖北省自然科学基金资助项目(2019CFB115)
更新日期/Last Update: 2022-02-09