[1]宋梦杨,连 方.连方教授治疗子宫内膜异位症经验[J].陕西中医,2022,(4):511-514.[doi:DOI:10.3969/j.issn.1000-7369.2022.04.026]
　SONG Mengyang,LIAN Fang.LIAN Fang's experience in treating endometriosis with Quyu Jiedu decoction[J].,2022,(4):511-514.[doi:DOI:10.3969/j.issn.1000-7369.2022.04.026]
点击复制

连方教授治疗子宫内膜异位症经验
分享到：

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2022年4期
页码:
511-514
栏目:
名中医经验
出版日期:
2022-04-05

文章信息/Info

Title:
LIAN Fang's experience in treating endometriosis with Quyu Jiedu decoction
作者:
宋梦杨1; 连 方2
(1.山东中医药大学,山东 济南 250355; 2.山东中医药大学附属医院,山东 济南 250014)
Author(s):
SONG Mengyang; LIAN Fang
(Shandong University of Traditional Chinese Medicine, Jinan 250355,China)
关键词:
子宫内膜异位症;  祛瘀解毒方;  病因病机;  痛经;  连方;  名医经验
Keywords:
Endometriosis;  Quyu Jiedu decoction;  Etiology and pathogenesis;  Dysmenorrhea;  LIAN Fang;  Famous doctors' experience
分类号:
R 711.71
DOI:
DOI:10.3969/j.issn.1000-7369.2022.04.026
文献标志码:
A
摘要:
导师连方教授通过近40年丰富的临床经验,分析总结提出了“血瘀蕴毒”伤络是子宫内膜异位症的基本病因病机。瘀血、恶血壅阻于冲任胞宫胞脉,血瘀久久不退,可蕴化为毒,从而转化为瘀毒,在疾病的发展过程中,瘀、毒相交共同对机体造成损害。连教授采用自拟祛瘀解毒方治疗子宫内膜异位症,以活血祛瘀、解毒散结、通络止痛为基本治疗法则,运用中医四诊合参,病证结合,根据不同症状临证另有灵活加减,标本兼顾,治疗本病,临床颇有成效,充分体现了中医药的整体调节之优势。笔者有幸跟师学习,采用归纳整理、对比分析的方法,从西医角度、中医病因病机、临床辨证论治、临证典型医案举例分析等方面对连方教授治疗子宫内膜异位症的临证经验进行总结。
Abstract:
Through nearly 40 years of clinical experience,Prof.LIAN Fang,our mentor,analyzed and concluded that “blood stasis and toxicity” is the basic cause and mechanism of endometriosis.Blood stasis and malignant blood are obstructed in the blood vessels of the uterus,and blood stasis that does not subside for a long time can be transformed into toxicity,thus transforming into stasis and toxicity,and in the process of disease development,stasis and toxicity intersect to cause damage to the body.Prof.LIAN Fang use self-developed formula Quyu Jiedu decoction to remove blood stasis and detoxify endometriosis,the basic treatment method is to activate blood circulation,remove blood stasis,detoxify and disperse nodules,and relieve pain.The use of the four diagnoses of Chinese medicine,the combination of disease and evidence,and the flexible addition and subtraction according to the different symptoms of the clinical evidence,the treatment of this disease is quite effective,which fully reflects the advantages of the overall regulation of Chinese medicine.This paper summarizes Prof.LIAN Fang's clinical experience in the treatment of endometriosis from the perspective of western medicine,the etiology and pathogenesis of Chinese medicine,clinical diagnosis and treatment,and the analysis of typical clinical cases with examples.

参考文献/References:

[1] 李秀娟,曾 娟,郑雪绒.轻刮子宫内膜对胚胎着床因子和反复妊娠失败患者妊娠结局影响研究[J].陕西医学杂志,2020,49(1):76-79.
[2] 许廷兰,王 洲,李团结,等.超声联合血清CA125、AMH、HE4在卵巢子宫内膜异位症囊肿和卵巢癌中的鉴别价值[J].中南医学科学杂志,2021,49(5):587-590.
[3] 高 扬,朱 艳.子宫内膜异位症合并不孕患者血清中基质金属蛋白酶-9、基质金属蛋白酶抑制剂-1、血管内皮生长因子可溶性受体、胰岛素生长因子-1、单核细胞趋化蛋白-1表达水平及临床意义[J].陕西医学杂志,2020,49(4):462-465,501.
[4] 王新香,张朝红.血清性激素和胰岛素水平对子宫内膜异位症合并不孕症的预测价值[J].陕西医学杂志,2021,50(1):41-43.
[5] 曲春尧.左炔诺孕酮宫内节育系统治疗卵巢子宫内膜异位症复发的效果观察[J].中国民康医学,2018,30(21):19-21.
[6] 索青霞,成 丽,王纪元,等.肿瘤坏死因子与子宫内膜异位症相关性研究[J].陕西医学杂志,2018,47(3):311-313.
[7] 刘 枚.少腹逐瘀汤联合孕三稀酮治疗子宫内膜异位症前瞻性研究[J].陕西中医,2020,41(3):342-345.
[8] 张红艳.腹腔镜手术联合辅助生殖技术治疗子宫内膜异位症不孕效果研究[J].中国医疗器械信息,2018,24(12):120-121.
[9] 叶远征,王彦红,何 艳,等.腹腔镜不同术式治疗卵巢子宫内膜异位囊肿疗效及安全性的系统评价[J].中国循证医学杂志,2013,13(1):55-61.
[10] 张丽梅.子宫内膜异位症的中医辨证治疗与临床疗效研究[J].中国医药指南,2017,15(4):181-182.
[11] 孙伟伟,杨艳环,郝增平,等.丹赤饮对子宫内膜异位症患者血清白细胞介素的影响[J].中国中医药信息杂志,2014,21(6):14-17.
[12] 张 莉,金 晶,季 菲.丹莪妇康煎膏联合孕三烯酮治疗子宫内膜异位症疗效及对患者CA125、TNF-α和IL-6水平的影响[J].陕西中医,2020,41(10):1370-1372.
[13] 李 潇,周艳艳.补肾活血方对肾虚血瘀型子宫内膜异位症不孕患者子宫内膜容受性的影响[J].陕西中医,2018,39(3):341-344.
[14] 文 怡,魏绍斌,刘 龙,等.子宫内膜异位症与子宫腺肌病中医证候分布规律的对比研究[J].辽宁中医杂志,2012,39(6):1025-1028.
[15] 连 方,王希波,张建伟,等.中医治疗子宫内膜异位症的思路与方法[J].中医杂志,2002,43(7):545-546.
[16] 连 方.子宫内膜异位症病机——瘀毒学说[J].中国中西医结合杂志,2008,28(11):968-969.
[17] 戚 敏,张建伟,李 杰.连方教授治疗子宫内膜异位症经验[J].湖南中医杂志,2013,29(7):36-37.
[18] 庞佳欢,夏亲华.活血化瘀软坚散结法治疗子宫内膜异位症患者的疗效及对体液免疫因子的影响[J].世界中医药,2019,14(10):2711-2715.
[19] 姚馨怡,陈 超,郑晓沛.活血化瘀软坚散结法对子宫内膜异位症体液细胞免疫因子影响及疗效观察[J].四川中医,2019,37(10):157-160.
[20] 刘亚妮,符雅惠,孟凡峰.补肾化瘀汤联合米非司酮治疗卵巢子宫内膜异位症临床观察[J].陕西中医,2017,38(10):1343-1344.
[21] 陆连英.《本草纲目》中红藤本草考证[J].时珍国医国药,2000,11(2):170.
[22] 温 薇.丹参的药理作用及临床应用[J].中医药信息,2007,24(4):54-55.
[23] 连 方,刘海萍,王云霞,等.祛瘀解毒法治疗瘀毒型子宫内膜异位症的机理探讨[J].中国中西医结合杂志,2006,26(2):110-113.

相似文献/References:

[1]胡贞君,刘笑梅△,曹保利.复方莪术散治疗子宫内膜异位症疗效及其分子学研究进展*[J].陕西中医,2019,(9):1315.
[2]张 莉,金 晶,季 菲△.丹莪妇康煎膏联合孕三烯酮治疗子宫内膜异位症疗效及对患者CA125、TNF-α和IL-6水平的影响*[J].陕西中医,2020,(10):1370.[doi:DOI:10.3969/j.issn.1000-7369.2020.10.007]
[3]李承秋,吕文艺,金 凡,等.活血消异汤联合米非司酮对子宫内膜异位症患者血清MMP-3、CA125、EMAb水平的影响[J].陕西中医,2021,(3):297.[doi:DOI:10.3969/j.issn.1000-7369.2020.03.006]
　LI Chengqiu,LV Wenyi,JIN Fan,et al.Effect of Huoxue Xiaoyi decoction combined with mifepristone on the serum levels of MMP-3,CA125 and EMAb in patients with endometriosis[J].,2021,(4):297.[doi:DOI:10.3969/j.issn.1000-7369.2020.03.006]
[4]陈亚杰,闻 姬.子宫内膜异位症中西医认识及治疗研究进展[J].陕西中医,2021,(10):1486.[doi:DOI:10.3969/j.issn.1000-7369.2020.10.043]
[5]余 震,柳 洲.消瘤方对子宫内膜异位症大鼠盆腔粘连的影响[J].陕西中医,2022,(1):13.[doi:DOI:10.3969/j.issn.1000-7369.2022.01.003]
　YU Zhen,LIU Zhou.Effect and the mechanism of Xiaoliu decoction on pelvic adhesion in rats with endometriosis[J].,2022,(4):13.[doi:DOI:10.3969/j.issn.1000-7369.2022.01.003]
[6]董秀娟,曹若愚,于洪基,等.大蒜素对子宫内膜异位症大鼠异位病灶及缺氧诱导因子-1α表达的影响[J].陕西中医,2022,(4):432.[doi:DOI:10.3969/j.issn.1000-7369.2022.04.005]
　DONG Xiujuan,CAO Ruoyu,YU Hongji,et al.Effects of Allicin on the ectopic lesions and the expression of HIF-1α in rats with endometriosis[J].,2022,(4):432.[doi:DOI:10.3969/j.issn.1000-7369.2022.04.005]
[7]赵 娜,周灵雪,杨向荣.桂枝茯苓胶囊联合戈舍瑞林对子宫内膜异位症患者子宫动脉血流动力学及Th1/Th2细胞因子的影响[J].陕西中医,2022,(4):446.[doi:DOI:10.3969/j.issn.1000-7369.2022.04.008]
　ZHAO Na,ZHOU Lingxue,YANG Xiangrong.Effects of Guizhi Fuling capsule combined with goserelin on uterine artery hemodynamics and Th1/Th2 cytokines in endometriosis patients[J].,2022,(4):446.[doi:DOI:10.3969/j.issn.1000-7369.2022.04.008]
[8]刘 叶,赵亚芹.活血通络解毒汤治疗子宫内膜异位症疗效及对患者卵巢功能的影响[J].陕西中医,2022,(4):450.[doi:DOI:10.3969/j.issn.1000-7369.2022.04.009]
　LIU Ye,ZHAO Yaqin.Therapeutic effect of Huoxue Tongluo Jiedu decoction on endometriosis and its influence on ovarian function of patients[J].,2022,(4):450.[doi:DOI:10.3969/j.issn.1000-7369.2022.04.009]
[9]杨润雨,陈 瑶,冯晓玲.中医药治疗子宫内膜异位症致不孕研究进展[J].陕西中医,2023,(5):670.[doi:DOI:10.3969/j.issn.1000-7369.2023.05.032]
　YANG Runyu,CHEN Yao,FENG Xiaoling.Research progress of traditional Chinese medicine in the treatment of infertility caused by endometriosis[J].,2023,(4):670.[doi:DOI:10.3969/j.issn.1000-7369.2023.05.032]
[10]赵佳琪,刘凯莉,李昱帅,等.子宫内膜异位症相关通路及中医药干预研究进展[J].陕西中医,2023,(9):1316.[doi:DOI:10.3969/j.issn.1000-7369.2023.09.038]
　ZHAO Jiaqi,LIU Kaili,LI Yushuai,et al.Research progress on the related pathways of endometriosis and the intervention of traditional Chinese medicine[J].,2023,(4):1316.[doi:DOI:10.3969/j.issn.1000-7369.2023.09.038]

备注/Memo

备注/Memo:
基金项目:国家自然科学基金资助面上项目(81774355); 山东省重大创新工程项目(2018CXGC1302); 连方山东省名老中医药专家传承工作室建设项目[鲁卫函(2019)92号]; 中医药传承与创新“百千万”人才工程岐黄学者建设项目[国中医药人教函(2018)284号]
更新日期/Last Update: 2022-04-08