[1]兰 谢,余帅江.温针灸对中风后遗症患者血清炎症因子的影响[J].陕西中医,2022,(7):954-957.[doi:DOI:10.3969/j.issn.1000-7369.2022.07.035]
 LAN Xie,YU Shuaijiang.Effects of warm acupuncture and moxibustion on serum inflammatory factor in patients with stroke sequelae[J].,2022,(7):954-957.[doi:DOI:10.3969/j.issn.1000-7369.2022.07.035]
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温针灸对中风后遗症患者血清炎症因子的影响
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2022年7期
页码:
954-957
栏目:
针灸经络
出版日期:
2022-07-05

文章信息/Info

Title:
Effects of warm acupuncture and moxibustion on serum inflammatory factor in patients with stroke sequelae
作者:
兰 谢余帅江
(成都市第三人民医院康复医学科,四川 成都 610036)
Author(s):
LAN XieYU Shuaijiang
(Department of Rehabilitation Medicine,Chengdu Third People's Hospital,Chengdu 610036,China)
关键词:
中风 脑卒中后遗症 温针灸 一氧化氮 同型半胱氨酸 Barthel指数
Keywords:
Stroke Stroke sequelae Warm acupuncture and moxibustion Nitric oxide Homocysteine Barthel index
分类号:
R 743.3
DOI:
DOI:10.3969/j.issn.1000-7369.2022.07.035
文献标志码:
A
摘要:
目的:探讨温针灸对中风后遗症患者疗效及对血清炎症因子水平的影响。方法:将80例患者随机分为观察组和对照组,对照组39例采用常规西医治疗,观察组41例采用温针灸治疗,观察对比两组临床疗效、中医证候积分、美国国立卫生院神经功能缺损(NIHSS)评分、肢体运动功能评分(FMA)、Barthel指数、血清同型半胱氨酸(Hcy)、一氧化氮(NO)、中枢神经特异性蛋白(S100-β)、肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP)、白介素-6(IL-6)水平等。结果:治疗后观察组总有效率和中医证候积分显著高于对照组(P<0.05); 观察组NIHSS评分、血清Hcy、NO、TNF-α、S100-β、CRP、IL-6水平均较对照组显著降低(P<0.05); FMA评分、Barthel指数均较对照组显著升高(P<0.05)。结论:温针灸对中风后遗症有较好的疗效,能有效降低血清Hcy、TNF-α及NO水平,抑制炎症反应,改善患者神经功能,有助于患者恢复。
Abstract:
Objective:To investigate the effect of warm acupuncture and moxibustion on serum inflammatory factor levels in patients with stroke sequelae and to observe the clinical efficacy.Methods:80 patients were randomly divided into observation group and control group,39 cases in the control group were treated with conventional western medicine,and 41 cases in the observation group were treated with warm acupuncture and moxibustion.Clinical curative effect,TCM syndrome score,NIHSS score,FMA score,Barthel index,serum homocysteine(Hcy),nitric oxide(NO),central nervous system specific protein(S100-β),tumor necrosis factor-α(TNF-α),C-reactive protein(CRP),interleukin-6(IL-6)levels were compared between the two groups.Results:After treatment,the total effective rate and TCM syndrome scores of the observation group were significantly higher than those of the control group(P<0.05); NIHSS score,serum Hcy,NO,TNF-α,S100-β,CRP,IL-6 levels in observation group were higher than those of the control group significantly decreased(P<0.05); FMA score and Barthel index were significantly higher than those in the control group(P<0.05).Conclusion:Warm acupuncture and moxibustion has a good curative effect,can effectively reduce serum Hcy,TNF-α and NO levels,reduce inflammatory response,enhance patients' neurological function,and help patients recover.

参考文献/References:

[1] 赵立伟,李 芳.替罗非班联合丁苯酞治疗进展性脑卒中对患者 P-selectin、CD63、CD62p水平及预后的影响[J].陕西医学杂志,2021,50(1):89-92.
[2] 李莎莎,李 璐,付锦锦,等.中西医结合治疗中风后遗症疗效的Meta分析[J].中日友好医院学报,2021,35(3):181-182.
[3] Akinyemi RO,Ovbiagele B,Adeniji OA,et al.Stroke in Africa:Profile,progress,prospects and priorities[J].Nature Reviews Neurology,2021,17(10):634-656.
[4] 聂芬芬,胡 莎,周丽莎,等.针刺治疗中风后失眠临床疗效Meta分析[J].陕西中医,2020,41(1):121-126.
[5] 张伯礼,吴勉华.中医内科学[M].4版.北京:中国中医药出版社,2016:63-472.
[6] 中国卒中学会,中国卒中学会神经介入分会,中华预防医学会卒中预防与控制专业委员会介入学组.急性缺血性卒中血管内治疗中国指南(2018)[J].中国卒中杂志,2018,13(7):706-729.
[7] 中华人民共和国卫生部.中药新药临床研究指导原则(试行)[M].北京:中国医药科技出版社,2002:128-137.
[8] 黄 泽,陈莲梅,阮茶梅,等.中西医结合治疗中风后遗症的研究进展[J].湖南中医杂志,2020,36(10):177-180.
[9] Broussy S,Rouanet F,Lesaine E,et al.Post-stroke pathway analysis and link with one year sequelae in a French cohort of stroke patients:The PAPASePA protocol study[J].BMC Health Services Research,2019,19(1):770.
[10] 韩墨洋.不同针灸方法对气虚血瘀型中风后遗症疗效的差异性分析[J].中西医结合心脑血管病杂志,2020,18(3):403-406.
[11] Maida CD,Norrito RL,Daidone M,et,al.Neuroinflammatory mechanisms in ischemic stroke:Focus on cardioembolic stroke,background,and therapeutic approaches[J].International Journal Molecular Sciences,2020,21(18):6454.
[12] Iadecola C,Buckwalter MS,Anrather J.Immune responses to stroke:Mechanisms,modulation,and therapeutic potential[J].The Journal of Clinical Investigation,2020,130(6):2777-2788.
[13] 焦 珂,苏同生.黄元御论治中风对温针灸治疗中风后遗症主穴选择之启示[J].中医学报,2020,35(5):956-959.
[14] 李哲楠,贾红玲.针灸治疗中风先兆的临床研究进展[J].中西医结合心脑血管病杂志,2019,17(4):533-535.
[15] 梁士锋.针灸联合康复训练对脑卒中后遗症治疗的效果分析[J].山西医药杂志,2019,48(18):2239-2240.
[16] 任 亮,刘 静.针灸治疗对脑中风后遗症患者的临床疗效及患者认知功能的影响[J].贵州医药,2019,43(12):1956-1957.
[17] 阎登富,余建萍,张黎黎,等.血府逐瘀汤配合针灸治疗对缺血性脑卒中偏瘫患者颅内血流动力学、肢体运动功能和生命质量的影响[J].世界中医药,2019,14(4):1028-1031.
[18] Engler-Chiurazzi EB,Monaghan KL,Wan ECK,et al.Role of B cells and the aging brain in stroke recovery and treatment[J].Geroscience,2020,42(5):1199-1216.
[19] 李 丹,迟丽屹.急性脑卒中患者血清氧化应激水平与睡眠障碍相关性研究[J].陕西医学杂志,2021,50(10):1250-1252,1256.
[20] 李 丹,杨吉睿.短暂性脑缺血发作早期卒中风险预测量表评分及血清学指标在脑卒中后眩晕评估中的价值研究[J].陕西医学杂志,2021,50(7):864-866.

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备注/Memo

备注/Memo:
基金项目:四川省卫生健康委员会科研项目(18PJ108)
更新日期/Last Update: 2022-07-07