[1]钟敏林,周仙仕,李 俊,等.血流感染脓毒症患者687例临床特征、中医证素分布及其与预后的相关性分析[J].陕西中医,2022,(10):1392-1395.[doi:DOI:10.3969/j.issn.1000-7369.2022.10.016]
　ZHONG Minlin,ZHOU Xianshi,LI Jun,et al.Clinical characteristics,distribution of TCM syndrome elements and their correlation with prognosis in 687 patients with sepsis and bloodstream infection[J].,2022,(10):1392-1395.[doi:DOI:10.3969/j.issn.1000-7369.2022.10.016]
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血流感染脓毒症患者687例临床特征、中医证素分布及其与预后的相关性分析
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2022年10期
页码:
1392-1395
栏目:
临床研究
出版日期:
2022-10-05

文章信息/Info

Title:
Clinical characteristics,distribution of TCM syndrome elements and their correlation with prognosis in 687 patients with sepsis and bloodstream infection
作者:
钟敏林1; 2; 周仙仕2; 李 俊2; 唐光华2
(1.广州中医药大学,广东 广州 510120; 2.广东省中医院急诊科,广东 广州 510120)
Author(s):
ZHONG Minlin; ZHOU Xianshi; LI Jun; TANG Guanghua
(Guangzhou University of Traditional Chinese Medicine,Guangzhou 510120,China)
关键词:
脓毒症;  血流感染;  临床特征;  证素;  预后;  回归性分析
Keywords:
Sepsis;  Bloodstream infection;  Clinical features;  Syndrome elements;  Prognosis;  Regression analysis
分类号:
R 631
DOI:
DOI:10.3969/j.issn.1000-7369.2022.10.016
文献标志码:
A
摘要:
目的:探讨血流感染脓毒症患者临床特征、中医证素分布及其与预后的相关性。方法:根据687例血流感染脓毒症患者住院期间预后分为存活组和病死组,分析两组临床特征的差异,并采用Cox回归分析影响预后的相关因素。结果:687例血流感染脓毒症患者中男性、老年人比例较高,常合并多种基础疾病,感染的病原体以革兰阴性菌(G-菌)多见; 中医证素以气虚证、热证、痰证、血瘀证及湿证比例最高。多因素Cox回归分析结果提示,年龄、热证、湿证、水饮证和阳虚证是血流感染脓毒症患者住院期间死亡的独立危险因素(均P<0.05)。结论:血流感染脓毒症患者的临床特点和预后有一定规律,当患者年龄较大,或者出现热证、湿证、水饮证或者阳虚证时,可能预后不良。
Abstract:
Objective:To explore the clinical characteristics,distribution of TCM syndrome elements and its correlation with prognosis in patients with sepsis and bloodstream infection.Methods:The patients of 687 patients with sepsis and bloodstream infection were divided into survival group and death group according to the prognosis during hospitalization.The differences of clinical characteristics between the two groups were analyzed,and the related factors affecting the prognosis were analyzed by Cox regression.Results:The proportion of male and elderly in 687 patients with sepsis caused by blood influenza was high,and they were often complicated with a variety of basic diseases.The pathogen of infection was Gram-negative bacteria(G-bacteria); Qi deficiency syndrome,heat syndrome,phlegm syndrome,blood stasis syndrome and dampness syndrome account for the highest proportion of TCM syndromes.Multivariate Cox regression analysis showed that age,heat syndrome,dampness syndrome,water drinking syndrome and yang deficiency syndrome were independent risk factors for death in patients with sepsis and bloodstream infection.Conclusion:The clinical characteristics and prognosis of patients with sepsis and bloodstream infection have certain rules.When the patients are older,or have heat syndrome,dampness syndrome,water drinking syndrome or yang deficiency syndrome,the prognosis may be poor.

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备注/Memo

备注/Memo:
基金项目:广东省基础与应用基础研究基金资助项目(2020A1515010512)
更新日期/Last Update: 2022-10-09