[1]杨润雨,陈 瑶,冯晓玲.中医药治疗子宫内膜异位症致不孕研究进展[J].陕西中医,2023,(5):670-673.[doi:DOI:10.3969/j.issn.1000-7369.2023.05.032]
　YANG Runyu,CHEN Yao,FENG Xiaoling.Research progress of traditional Chinese medicine in the treatment of infertility caused by endometriosis[J].,2023,(5):670-673.[doi:DOI:10.3969/j.issn.1000-7369.2023.05.032]
点击复制

中医药治疗子宫内膜异位症致不孕研究进展
分享到：

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2023年5期
页码:
670-673
栏目:
综 述
出版日期:
2023-05-05

文章信息/Info

Title:
Research progress of traditional Chinese medicine in the treatment of infertility caused by endometriosis
作者:
杨润雨1; 陈 瑶1; 冯晓玲2
(1.黑龙江中医药大学,黑龙江 哈尔滨 150040; 2.黑龙江中医药大学附属第一医院,黑龙江 哈尔滨 150040)
Author(s):
YANG Runyu; CHEN Yao; FENG Xiaoling
(Heilongjiang University of Traditional Chinese Medicine,Harbin 150040,China)
关键词:
子宫内膜异位症;  不孕;  内治法;  外治法;  整体观念;  辨证论治
Keywords:
Endometriosis;  Infertility;  Internal treatment;  External treatment;  Holistic concept;  Dialectical treatment
分类号:
R 711.71
DOI:
DOI:10.3969/j.issn.1000-7369.2023.05.032
文献标志码:
A
摘要:
子宫内膜异位症(EMT)是导致不孕的相关因素之一,其发病机制复杂,临床对于本病的治疗一直是妇科热点问题。在EMT致不孕的治疗中,中医药充分发挥了整体观念和辨证论治的优势,将中医的病因病机理论和西医病因病理相结合,通过采用内治法、外治法和中医药联合西医等方法对本病进行治疗,效果显著。现将对中医药治疗子宫内膜异位症致不孕的疗法进行探析。
Abstract:
Endometriosis(EMT)is one of the related factors leading to infertility,its pathogenesis is complex,and the clinical treatment of this disease has always been a hot issue in gynecology.In the treatment of EMT-induced infertility,Chinese medicine gives full play to the advantages of holistic concept and dialectical treatment,combined with the etiology mechanism of traditional Chinese medicine and the cause of western medicine,and treats the disease through internal treatment,external treatment,staging treatment,type treatment,etiology treatment,etc.,with remarkable results.In this article,we will analyze the therapy of traditional Chinese medicine for the etiology and mechanism of infertility caused by endometriosis.

参考文献/References:

[1] 刘 丹,梁新新.育龄期子宫内膜异位症合并不孕症患者临床特征及腹腔镜术后辅助生殖妊娠结局影响因素分析[J].陕西医学杂志,2021,50(4):409-412,420.
[2] 张久红.子宫内膜异位症相关不孕的治疗研究进展[J].实用妇科内分泌杂志:电子版,2018,5(28):10,14.
[3] Buyalos RP,Agarwal SK.Endometriosis-associated infertility[J].Curr Opin Obstet Gynecol,2000,12(5):377-381.
[4] 陈亚杰,闻 姬.子宫内膜异位症中西医认识及治疗研究进展[J].陕西中医,2021,42(10):1486-1489.
[5] 张 玙,窦 真,夏 天,等.中医分期论治子宫内膜异位症所致不孕症验案2则[J].湖南中医杂志,2020,36(1):77-78.
[6] 方庆霞,高山凤,徐 耀,等.李坤寅教授以瘀为本分期辨治子宫内膜异位症性不孕[J].湖南中医药大学学报,2021,41(12):1943-1946.
[7] 陈 颐,司徒仪.司徒仪教授治疗子宫内膜异位症的中医辨证思路与经验[J].新中医,2011,43(12):154-155.
[8] 马 堃,陈燕霞,李 敏.补肾活血法治疗子宫内膜异位症不孕的临床经验[J].中国中药杂志,2019,44(6):1094-1098.
[9] 赵芳芳,魏宏艳,段 楠,等.子宫内膜异位症致不孕的中医证候及用药规律研究[J].中医药临床杂志,2021,33(6):1147-1150.
[10] 姜 晶,杜菲菲,王佳楣,等.五子四物加减方治疗肾虚血瘀型子宫内膜异位症致不孕症的效果及对子宫内膜容受性影响[J].四川中医,2021,39(10):161-164.
[11] 张雪清.自拟四温汤治疗肝寒血瘀型不孕症的临床效果观察[J].中国医药指南,2019,17(35):175-176.
[12] 谷栩萌.基于PDGFR/JAK2/STAT3通路探讨痛愈舒颗粒对寒凝血瘀型EMs大鼠在位内膜的调控机制[D].哈尔滨:黑龙江中医药大学,2018.
[13] 鲜恩英,李雪琴,黄莉莉.益气补肾化瘀法周期性治疗子宫内膜异位症伴不孕的临床疗效[J].中华中医药学刊,2018,36(6):1471-1474.
[14] 王砚琳.补肾疏肝、痰瘀同治法治疗子宫内膜异位症临床观察[J].山东中医杂志,2003,22(4):207-208.
[15] Yoshida S,Harada T,Iwabe T.A combination of interleukin-6 and its soluble receptor impairs sperm motility:Implications in infertility associated with endometriosis[J].Hum Reprod,2004,19:1821-1825.
[16] Mansour G,Aziz N,Sharma R,et al.The impact of peritoneal fluid from healthy women and from women with endometriosis on sperm DNA and its relationship to the sperm deformity index[J].Fertil Steril,2009,92:61-67.
[17] 丁 宁,王 昕,夏晓杰.桂枝茯苓丸对子宫内膜异位症患者血清IL-2、IL-8、VEGF及卵巢功能影响[J].辽宁中医药大学学报,2019,21(3):110-113.
[18] Vivier E,Tomasello E,Baratin M,et al. Functions of natural killer cells[J].Nat Immunol,2008,9(5):503- 510.
[19] Indra DH,Diana A,Antonio GVJ,et al.Uterine natural killer cells:From foe to friend in reproduction[J].Hum Reprod Update,2021,27(4):720-746.
[20] 付 楝.补肾调经汤内服对子宫内膜异位症体液免疫及异位子宫内膜的影响 [J].陕西中医,2016,37(8):1051-1052.
[21] 金玉华.子宫内膜异位症合并不孕妇女内分泌的临床研究[J].实用妇科内分泌电子杂志,2019,6(22):58.
[22] 李宛蓉.加味内异痛经灵治疗肾虚血瘀型子宫内膜异位症不孕的疗效观察[D].南宁:广西中医药大学,2017.
[23] Valdes CT,Schutt A,Simon C.Implantation failure of endometrial origin:It is not pathology,but our failure to synchronize the developing embryo with a receptive endometrium[J].Fertil Steril,2017,108(1):15-18.
[24] Lessey BA,Kim JJ.Endometrial receptivity in the eutopic endometrium of women with endometriosis:It is affected:Let me show you why[J].Fertil Steril,2017,108(1):19-27.
[25] 朱靓雯,薛 晴.子宫内膜容受性与子宫内膜异位症相关性不孕[J].中华生殖与避孕杂志,2020,40(3):246-249.
[26] 张俊辉.补肾活血方对子宫内膜异位症不孕患者内膜容受性影响的临床疗效观察[D].太原:山西中医药大学,2020.
[27] 单海萍.针刺诱导排卵对PCOS和EMT的效应比较[D].南京:南京中医药大学,2021.
[28] 谢春丽,赵 星,朱兰妃,等.热敏灸联合腹腔镜手术治疗子宫内膜异位症不孕症疗效观察[J].上海针灸杂志,2021,40(5):576-580.
[29] 宫文彬.益肾化瘀汤内服配合中药外敷治疗子宫内膜异位症的临床探究[J].实用妇科内分泌电子杂志,2019,6(22):80-81.
[30] 张 澎,范郁山,苗芙蕊.中药灌肠治疗子宫内膜异位症的研究进展[J].湖南中医杂志,2017,33(9):198-199.
[31] 张凤敏,李艳梅,常珍珍,等.中西医结合治疗子宫内膜异位症相关性不孕疗效观察[J].山西中医药大学学报,2021,22(2):132-134.
[32] 赵 娜,周灵雪,杨向荣.桂枝茯苓胶囊联合戈舍瑞林对子宫内膜异位症患者子宫动脉血流动力学及Th1/Th2细胞因子的影响[J].陕西中医,2022,43(4):446-449.
[33] 翟 倩,陈秀英,卞 欣,等.调经止痛丸用于子宫内膜异位症腔镜术后患者疗效观察[J].辽宁中医杂志,2022,49(11):88-90.
[34] 王 娇.定坤丹联合腹腔镜治疗血瘀型子宫内膜异位症性不孕的临床研究[D].太原:山西中医药大学,2021.
[35] 陈湘榆.补肾养血方对肾虚血瘀型内异症不孕症IVF-ET干预妊娠结局的临床研究[D].南宁:广西中医药大学,2019.

相似文献/References:

[1]胡贞君,刘笑梅△,曹保利.复方莪术散治疗子宫内膜异位症疗效及其分子学研究进展*[J].陕西中医,2019,(9):1315.
[2]张 莉,金 晶,季 菲△.丹莪妇康煎膏联合孕三烯酮治疗子宫内膜异位症疗效及对患者CA125、TNF-α和IL-6水平的影响*[J].陕西中医,2020,(10):1370.[doi:DOI:10.3969/j.issn.1000-7369.2020.10.007]
[3]李承秋,吕文艺,金 凡,等.活血消异汤联合米非司酮对子宫内膜异位症患者血清MMP-3、CA125、EMAb水平的影响[J].陕西中医,2021,(3):297.[doi:DOI:10.3969/j.issn.1000-7369.2020.03.006]
　LI Chengqiu,LV Wenyi,JIN Fan,et al.Effect of Huoxue Xiaoyi decoction combined with mifepristone on the serum levels of MMP-3,CA125 and EMAb in patients with endometriosis[J].,2021,(5):297.[doi:DOI:10.3969/j.issn.1000-7369.2020.03.006]
[4]陈亚杰,闻 姬.子宫内膜异位症中西医认识及治疗研究进展[J].陕西中医,2021,(10):1486.[doi:DOI:10.3969/j.issn.1000-7369.2020.10.043]
[5]余 震,柳 洲.消瘤方对子宫内膜异位症大鼠盆腔粘连的影响[J].陕西中医,2022,(1):13.[doi:DOI:10.3969/j.issn.1000-7369.2022.01.003]
　YU Zhen,LIU Zhou.Effect and the mechanism of Xiaoliu decoction on pelvic adhesion in rats with endometriosis[J].,2022,(5):13.[doi:DOI:10.3969/j.issn.1000-7369.2022.01.003]
[6]郝雪芳,闻 姬.子宫内膜息肉切除术后预防复发中西医治疗进展[J].陕西中医,2022,(1):124.[doi:DOI:10.3969/j.issn.1000-7369.2022.01.032]
[7]董秀娟,曹若愚,于洪基,等.大蒜素对子宫内膜异位症大鼠异位病灶及缺氧诱导因子-1α表达的影响[J].陕西中医,2022,(4):432.[doi:DOI:10.3969/j.issn.1000-7369.2022.04.005]
　DONG Xiujuan,CAO Ruoyu,YU Hongji,et al.Effects of Allicin on the ectopic lesions and the expression of HIF-1α in rats with endometriosis[J].,2022,(5):432.[doi:DOI:10.3969/j.issn.1000-7369.2022.04.005]
[8]赵 娜,周灵雪,杨向荣.桂枝茯苓胶囊联合戈舍瑞林对子宫内膜异位症患者子宫动脉血流动力学及Th1/Th2细胞因子的影响[J].陕西中医,2022,(4):446.[doi:DOI:10.3969/j.issn.1000-7369.2022.04.008]
　ZHAO Na,ZHOU Lingxue,YANG Xiangrong.Effects of Guizhi Fuling capsule combined with goserelin on uterine artery hemodynamics and Th1/Th2 cytokines in endometriosis patients[J].,2022,(5):446.[doi:DOI:10.3969/j.issn.1000-7369.2022.04.008]
[9]刘 叶,赵亚芹.活血通络解毒汤治疗子宫内膜异位症疗效及对患者卵巢功能的影响[J].陕西中医,2022,(4):450.[doi:DOI:10.3969/j.issn.1000-7369.2022.04.009]
　LIU Ye,ZHAO Yaqin.Therapeutic effect of Huoxue Tongluo Jiedu decoction on endometriosis and its influence on ovarian function of patients[J].,2022,(5):450.[doi:DOI:10.3969/j.issn.1000-7369.2022.04.009]
[10]宋梦杨,连 方.连方教授治疗子宫内膜异位症经验[J].陕西中医,2022,(4):511.[doi:DOI:10.3969/j.issn.1000-7369.2022.04.026]
　SONG Mengyang,LIAN Fang.LIAN Fang's experience in treating endometriosis with Quyu Jiedu decoction[J].,2022,(5):511.[doi:DOI:10.3969/j.issn.1000-7369.2022.04.026]

备注/Memo

备注/Memo:
基金项目:国家自然科学基金资助项目(81973894)
更新日期/Last Update: 2023-05-09