[1]程晓嫚,田丽颖,王 芬,等.安胎方联合穴位贴敷治疗早期先兆流产疗效观察[J].陕西中医,2023,(9):1198-1201.[doi:DOI:10.3969/j.issn.1000-7369.2023.09.008]
　CHENG Xiaoman,TIAN Liying,WANG Fen,et al.Curative effect observation of Antai formula combined with acupoint application on early threatened abortion[J].,2023,(9):1198-1201.[doi:DOI:10.3969/j.issn.1000-7369.2023.09.008]
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安胎方联合穴位贴敷治疗早期先兆流产疗效观察
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2023年9期
页码:
1198-1201
栏目:
临床研究
出版日期:
2023-09-05

文章信息/Info

Title:
Curative effect observation of Antai formula combined with acupoint application on early threatened abortion
作者:
程晓嫚; 田丽颖; 王 芬; 成自霞; 聂 婷
(安徽中医药大学第二附属医院妇科,安徽 合肥 230061)
Author(s):
CHENG Xiaoman; TIAN Liying; WANG Fen; CHENG Zixia; NIE Ting
(Department of Gynaecology Second Affiliated Hospital Anhui University of Traditional Chinese Medicine,Hefei 230061,China)
关键词:
早期先兆流产;  肾虚证;  安胎方;  穴位贴敷;  黄体酮注射液;  激素水平
Keywords:
Early threatened abortion;  Kidney deficiency syndrome;  Antai formula;  Acupoint application;  Progesterone injection;  Hormone levels
分类号:
R 714.21
DOI:
DOI:10.3969/j.issn.1000-7369.2023.09.008
文献标志码:
A
摘要:
目的:观察安胎方联合穴位贴敷治疗早期先兆流产疗效及对患者激素水平、证候积分的影响。方法:选取早期先兆流产(肾虚证)患者62例,按随机数字表法分为对照组、观察组各31例,两组分别脱落1例,每组各剩30例,对照组予黄体酮注射液肌注; 观察组在肌注黄体酮注射液基础上予安胎方联合穴位贴敷。比较两组治疗前后孕酮(P)、人绒毛膜促性腺激素(β-HCG)、雌二醇(E2)及证候积分,比较两组症状缓解时间,评估疗效,并比较两组治疗后不良反应、随访至妊娠12周的胎儿颈项透明层(NT)正常率及满意度。结果:治疗后两组P、β-HCG、E2均升高,证候积分均降低,且观察组改善明显,症状缓解时间明显缩短,总有效率、NT正常率及满意度均较对照组高,差异均有统计学意义(均P<0.05); 两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:在肌注黄体酮注射液基础上,予安胎方联合穴位贴敷治疗早期先兆流产(肾虚证)可更好的调节患者激素水平,改善症状,提高疗效,且安全性及满意度高。
Abstract:
Objective:To observe the curative effect of Antai formula combined with acupoint application on early threatened abortion and the influence of hormone levels and syndrome score.Methods:62 cases of early threatened abortion(kidney deficiency syndrome),random number table method was used to divide 31 cases into control group and observation group.Two groups shed 1 case respectively,with 30 cases remaining in each group.The control group was injected intramuscularly with progesterone injection,on the basis,observation group was treated with Antai formula combined with acupoint application.Compared progesterone,β-human chorionic gonadotropin,estradiol(P,β-HCG,E2)and TCM syndrome score between groups before and after treatment,and the time of symptom relief,evaluate the efficacy,and compare the adverse reactions after treatment,the Nuchal translucency(NT)normal rate and satisfaction at 12 weeks of gestation between the two groups.Results:After treatment,P,β-HCG,E2 in groups were increased,the scores of syndrome were decreased,observation group improved more obviously,the time of symptom relief was shorter obviously,the total effective rate,NT normal rate and satisfaction degree were higher than control group,all with statistical significancet(all P<0.05).There was no significant difference in adverse reactions between the two groups(P>0.05).Conclusion:On the basis of intramuscular injection of progesterone,the treatment of early threatened abortion(kidney deficiency syndrome)with Antai formula combined with acupoint application can better regulate the levels of hormone levels,improve symptoms and therapeutic effect,and high safety and satisfaction.

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备注/Memo

备注/Memo:
基金项目:安徽省卫生健康科研项目(AHWJ2022b023); 田丽颖全国名老中医药专家传承工作室建设项目[国中医药人教函(2022)75号]; 安徽省“十三五”省级重点中医专科建设项目[卫办秘(2016)680号]
更新日期/Last Update: 2023-09-08