[1]谢晓敏,曹雪梅,吴泽婷,等.针灸联合四君子汤合四逆散加减对肝郁脾虚型失眠患者睡眠质量、睡眠时间的影响[J].陕西中医,2023,(10):1456-1460.[doi:DOI:10.3969/j.issn.1000-7369.2023.10.028]
　XIE Xiaomin,CAO Xuemei,WU Zeting,et al.Effect of acupuncture and moxibustion combined with Sijunzi decoction and Sini powder on sleep quality and sleep time of insomnia patients with liver depression and spleen deficiency[J].,2023,(10):1456-1460.[doi:DOI:10.3969/j.issn.1000-7369.2023.10.028]
点击复制

针灸联合四君子汤合四逆散加减对肝郁脾虚型失眠患者睡眠质量、睡眠时间的影响
分享到：

《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2023年10期
页码:
1456-1460
栏目:
针灸经络
出版日期:
2023-10-05

文章信息/Info

Title:
Effect of acupuncture and moxibustion combined with Sijunzi decoction and Sini powder on sleep quality and sleep time of insomnia patients with liver depression and spleen deficiency
作者:
谢晓敏1; 曹雪梅2; 吴泽婷1; 谭天辉1; 金维缘3
(1.广州中医药大学第四临床医学院,广东 深圳 518000; 2.深圳市中医院 深圳市针灸现代应用研究重点实验室,广东 深圳 518000; 3.广州市黄埔区疾病预防控制中心,广东 广州 510300)
Author(s):
XIE Xiaomin; CAO Xuemei; WU Zeting; TAN Tianhui; JIN Weiyuan
(The Fourth Clinical College of Guangzhou University of Chinese Medicine,Shenzhen 518000,China)
关键词:
失眠;  肝郁脾虚型;  针灸;  四君子汤合四逆散;  睡眠质量;  睡眠时间
Keywords:
Insomnia;  Liver depression and spleen deficiency type;  Acupuncture;  Sijunzi decoction and Sini powder;  Sleep quality;  Sleep duration
分类号:
R 256.23
DOI:
DOI:10.3969/j.issn.1000-7369.2023.10.028
文献标志码:
A
摘要:
目的:探讨针灸结合四君子汤合四逆散加减对肝郁脾虚型失眠患者的睡眠质量、睡眠时间的影响。方法:选择110例肝郁脾虚型失眠患者作为研究对象,按随机数字表法均分为对照组和观察组,各55例,对照组实施四君子汤合四逆散加减治疗,观察组在对照组基础上加针灸治疗。比较两组的匹兹堡睡眠质量指数(PSQI)、睡眠时间(慢波睡眠时间S3、S4及快动眼睡眠时间)、中医症候积分(主症总积分、次症总积分)、健康调查简表(SF-36)评分及临床疗效。结果:观察组治疗后1、2、4周的PSQI评分均低于对照组(P<0.05); 观察组治疗后的慢波睡眠时间S3、S4及快动眼睡眠时间高于对照组(P<0.05); 观察组治疗后的主症、次症总积分低于对照组(P<0.05); 观察组治疗后的认知能力、生理状态、情感与精神状态、社会功能高于对照组(P<0.05); 观察组总有效率高于对照组,差异有统计学意义(P<0.05)。结论:针灸结合四君子合四逆散加减治疗在肝郁脾虚型失眠中能达到较理想的治疗效果,能提高睡眠质量,改善失眠及睡眠状态,提升临床疗效。
Abstract:
Objective:To explore the effect of acupuncture and moxibustion combined with Sijunzi decoction and Sini powder on sleep quality and sleep time of insomnia patients with liver depression and spleen deficiency.Methods:A total of 110 cases of insomnia patients with liver-qi and spleen-deficiency treated were selected as research objects and divided into two groups(control group and observation group,55 cases each)according to random number table method.The treatment of Sijunzi decoction and Sini powder was performed,and the observation group was treated with acupuncture and moxibustion.Pittsburgh sleep quality index(PSQI),sleep duration(slow wave sleep duration S3,S4 and rapid eye movement sleep duration),TCM syndrome score(total score of major disease,total score of secondary disease),health survey Form(SF-36)score and clinical efficacy of the two groups were compared.Results:The PSQI scores of the observation group were lower than those of the control group at 1,2 and 4 weeks after treatment(P<0.05).The slow-wave sleep time S3,S4 and REM sleep time of the observation group after treatment were higher than those of the control group(P<0.05).The total scores of the main disease and secondary disease in the observation group were lower than those in the control group(P<0.05).The cognitive ability,physiological state,emotional and mental state and social function of the observation group were higher than those of the control group(P<0.05).The total effective rate of the observation group was higher than that of the control group.Conclusion:Acupuncture and moxibustion combined with Sijunzi plus Sini powder in the treatment of insomnia with liver depression and spleen deficiency can achieve ideal therapeutic effect,can improve sleep treatment,prolong sleep time,improve the insomnia symptoms of patients,improve their quality of life,can further improve the overall clinical efficacy.

参考文献/References:

[1] 王 菊,金 静.平衡火罐联合引阳入阴法治疗失眠临床研究[J].陕西中医,2019,40(3):344-346.
[2] 李小兰,马 浩.平肝活血方治疗肝郁瘀阻型失眠症伴记忆力减退疗效研究[J].陕西中医,2019,40(9):1177-1179.
[3] 乔 赟,熊鸣峰,王利勤,等.穴位贴敷联合四君子汤合四逆散加减治疗肝郁脾虚型失眠的临床疗效观察[J].实用中西医结合临床,2022,22(17):1-4,8.
[4] Yu KW,Tie L,Li JH,et al.Effectiveness and cerebral responses of multi-points acupuncture for primary insomnia:A preliminary randomized clinical trial and fMRI study[J].BMC Complement Med Ther,2020,20(1):254.
[5] Cong W,Wen LX,Guan WL,et al.Impact of acupuncture on sleep and comorbid symptoms for chronic insomnia:A randomized clinical trial[J].Nat Sci Sleep,2021,13(10):1807-1822.
[6] 中华医学会神经病学分会,中华医学会神经病学分会睡眠障碍学组,中华医学会神经病学分会神经心理与行为神经病学学组.中国成人失眠伴抑郁焦虑诊治专家共识[J].中华神经科杂志,2020,53(8):564-574.
[7] Clara SD,Jose LC,Ainhoa CC,et al.Brief version of the pittsburgh sleep quality index and measurement invariance across gender and age in a population-based sample[J].Psychol Assess,2021,33(2):111-121.
[8] 吴晓菊,邓燕妹,池晓玲.五行音乐疗法联合针刺治疗肝郁脾虚型慢性肝病伴失眠患者的临床疗效[J].中西医结合肝病杂志,2021,31(10):886-889.
[9] 文世虹.通调任督针刺法治疗失眠症的文献研究和临床研究[D].太原:山西中医药大学,2020.
[10] 刘 笑,陈丽敏,郑 肖.黄连阿胶汤联合穴位贴敷治疗围绝经期失眠的临床疗效和安全性分析[J].中国妇幼保健,2020,35(21):4049-4051.
[11] 慕 超,李 进,邢 亮,等.铜川市3～6岁儿童睡眠障碍发生情况及影响因素调查分析[J].陕西医学杂志,2021,50(6):759-762.
[12] 魏 荣,刘 鹏,田 甜,等.孕晚期孕妇睡眠质量及抑郁现状调查研究[J].陕西医学杂志,2020,49(2):247-249,253.
[13] 缑燕华.调任通督针法治疗失眠症的临床研究[D].广州:广州中医药大学,2012.
[14] 缑燕华,皮 敏.杨卓欣教授治疗失眠症经验简介[J].新中医,2011,43(7):177-178.
[15] 余 松,何 杰,张 颖.四逆散合四君子汤加味方联合保肝抗病毒药物治疗慢性乙型肝炎肝纤维化肝郁脾虚证42例临床研究[J].江苏中医药,2022,54(11):36-39.
[16] 马凌慧,马良宵,于文颜,等.基于复杂网络探析针灸治疗高血压合并失眠的临床规律[J].中医药导报,2022,28(11):147-152.
[17] Shu Y,He D,Li W,et al.Hepatoprotective effect of citrus aurantium against APAP-induced liver injury by regulating liver lipid metabolism and apoptosis[J].Int J Biol Sci,2020,16(5):752-765.
[18] Sameh SA,Fatma IS,Sun JZ,et al.Molecular characterization of virulence and drug resistance genes-producing escherichia coli isolated from chicken meat:Metal oxide nanoparticles as novel antibacterial agents[J].Microb Pathog,2020,143(8):104164.
[19] 王 意,王 茎,夏 冉,等.基于数据挖掘的古代文献中针灸治疗心痛腧穴运用规律研究[J].世界中医药,2022,17(11):1627-1632.
[20] Timothy JG,Philip G,Ming XY,et al.Genetic predictors of response to acupuncture or cognitive behavioral therapy for insomnia in cancer survivors:An exploratory analysis[J].J Pain Symptom Manage,2021,2(3):192-199.
[21] 龙迪和,刚丽丽,崔 晓,等.针灸对肝郁脾虚型失眠患者慢波睡眠时间与快动眼睡眠时间的影响[J].重庆医学,2021,50(15):2579-2582.

相似文献/References:

[1]王 菊,金 静.平衡火罐联合引阳入阴法治疗失眠临床研究*[J].陕西中医,2019,(3):344.
　WANG Ju,JIN Jing..Clinical studies of leading to Yinyang Ruyin cupping breath guiding massage on patients with insomnia[J].,2019,(10):344.
[2]侯杰军,路亚娥,吕 予,等.中医药治疗失眠临床研究进展*[J].陕西中医,2019,(2):270.
[3]王晓宇,张 玮,李华南,等.推拿手法治疗失眠心脾两虚证研究进展*[J].陕西中医,2019,(6):811.
[4]杨海侠,张晓乐△,李小波,等.补阴泻阳穴位按摩治疗失眠证疗效研究*[J].陕西中医,2019,(9):1291.
[5]张 喜,袁霭凤,宋 军△,等.失眠证候研究方法学进展及概况*[J].陕西中医,2019,(10):1483.
　ZHANG Xi,YUAN Aifeng,SONG Jun,et al.Progress of research methodology on TCM syndromes of insomnia[J].,2019,(10):1483.
[6]王诗恒,刘剑锋△,秦培洁,等.刘剑锋教授治疗失眠临床经验[J].陕西中医,2020,(1):95.
　WANG Shiheng,LIU Jianfeng,QIN Peijie,et al.Professor Liu Jianfeng’s clinical experience in treating insomnia[J].,2020,(10):95.
[7]姚嘉良,田建辉.论形神并调治疗肿瘤相关性失眠*[J].陕西中医,2020,(2):213.
　YAO Jialiang,TIAN Jianhui..Adjusting physiological and psychological function to treat cancer-related insomnia[J].,2020,(10):213.
[8]贺 挺,吴文忠△.针灸“同病异治”失眠症临床研究*[J].陕西中医,2020,(12):1806.[doi:DOI:10.3969/j.issn.1000-7369.2020.12.034]
[9]郭仲凯,周永学,李翠娟.基于药机对应探析仲景治疗失眠的基本方法[J].陕西中医,2021,(11):1594.[doi:DOI:10.3969/j.issn.1000-7369.2020.11.023]
[10]党星星,王 翠,韩祖成,等.基于数据挖掘分析韩祖成治疗失眠组方规律[J].陕西中医,2021,(12):1769.[doi:DOI:10.3969/j.issn.1000-7369.2020.12.031]

备注/Memo

备注/Memo:
基金项目:国家自然科学基金资助项目(81603417); 广东省针灸学会科研基金资助项目(GDZJ2022004)
更新日期/Last Update: 2023-10-09