[1]屈钰珂,唐旭东,俞赟丰,等.基于“相火在位”理论探讨藏肾疏肝法治疗溃疡性结肠炎[J].陕西中医,2024,(2):226-229.[doi:DOI:10.3969/j.issn.1000-7369.2024.02.017]
　QU Yuke,TANG Xudong,YU Yunfeng,et al.Discussion of treatmenting ulcerative colitis by the method of sealing the kidney and dispersing the liver based on “ministerial fire in position” theory[J].,2024,(2):226-229.[doi:DOI:10.3969/j.issn.1000-7369.2024.02.017]
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基于“相火在位”理论探讨藏肾疏肝法治疗溃疡性结肠炎
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《陕西中医》[ISSN:1000-7369/CN:61-1281/TN]

卷:
期数:
2024年2期
页码:
226-229
栏目:
学术探讨
出版日期:
2024-02-05

文章信息/Info

Title:
Discussion of treatmenting ulcerative colitis by the method of sealing the kidney and dispersing the liver based on “ministerial fire in position” theory
作者:
屈钰珂; 唐旭东; 俞赟丰; 龙 丹; 朱 莹
(湖南中医药大学第一附属医院,湖南 长沙 410021)
Author(s):
QU Yuke; TANG Xudong; YU Yunfeng; LONG Dan; ZHU Ying
(The First Affiliated Hospital of Hunan University of Chinese Medicine,Changsha 410021,China)
关键词:
溃疡性结肠炎;  肠癖;  泄泻;  便血;  相火在位;  藏肾疏肝法
Keywords:
Ulcerative colitis;  Spouting bleeding from anus;  Diarrhea;  Blood in the stool;  Ministerial fire in position;  The method of sealing the kidney and dispersing the liver
分类号:
R 516.1
DOI:
DOI:10.3969/j.issn.1000-7369.2024.02.017
文献标志码:
A
摘要:
溃疡性结肠炎属于炎症性肠病,其发病机制与肠道免疫紊乱相关。近年来有学者根据相火生理病理特点提出“相火免疫”学说。通过梳理“相火在位”的理论内涵,认为相火在位与肾精封藏、肝气疏泄具有生理相关性,结合溃疡性结肠炎临床症状及病理基础,认为“肾失封藏、相火妄动”是溃疡性结肠炎发病的根本病机,并提出藏肾疏肝的治疗大法,以填补下焦,封髓藏肾固其根本,配合清遏余邪、疏肝敛阳以治其标,分予清热疏肝、利湿化浊、散瘀解毒以“消、敛、降”妄火,标本兼治,为中医辨治溃疡性结肠炎提供新思路。
Abstract:
Ulcerative colitis is an inflammatory bowel disease,and its pathogenesis is related to intestinal immune disorders.In recent years,some scholars have proposed the theory of “ministerial fire immunity” based on the physiopathological characteristics of ministerial fire.In this paper,by sorting out the theoretical connotation of “ministerial fire in position”,we believe that ministerial fire in position is physiologically related to kidney essence sealing and liver controlling dispersion,and combined with the clinical symptoms and pathological basis of ulcerative colitis,we believe that “loss of kidney sealing and hyperactivity of ministerial fire” is the fundamental pathogenesis of ulcerative colitis.We proposed the treatment method of sealing the kidney and dispersing the liver,seal the marrow and hide the kidney to consolidate its root,together with clearing and suppressing residual evil,dredging the liver and regulating yang to treat its symptoms,and dividing heat and dispersing the liver,relieving dampness and removing turbidity,dispersing blood stasis and detoxifying the delusional fire to “eliminate,converge and lower” the frenetic fire,providing new ideas for the identification and treatment of ulcerative colitis in Chinese medicine.

参考文献/References:

[1] 王春霞,葛俊李,李芳,等.中药治疗溃疡性结肠炎作用及机制研究进展[J].中国实验方剂学杂志,2023,29(2):270-282.
[2] 安敏,高振军.美沙拉秦长期治疗对溃疡性结肠炎患者结肠黏膜癌相关基因表达的影响[J].陕西医学杂志,2021,50(4):485-488.
[3] 陈玉林,董甲庆.复方谷氨酰胺颗粒与肠内营养治疗溃疡性结肠炎临床研究[J].陕西医学杂志,2020,49(1):115-117,129.
[4] 叶雪珂,单国顺,付郁,等.溃疡性结肠炎发病机制及中西医治疗的研究进展[J].中华中医药学刊,2022,40(9):158-162,281.
[5] 朱震亨.格致余论[M].北京:中国医药科技出版社,2018:44.
[6] 张钰欣,王雨,马博雅,等.李杲阴火理论研究探析[J].陕西中医,2020,41(3):364-367.
[7] 张志聪.黄帝内经素问集注[M].北京:中国医药科技出版社,2014:17.
[8] 龚廷贤.万病回春[M].北京:中国中医药出版社,2019:115.
[9] 张铁军,张雪娟,董燕平.董燕平教授从相火妄动论治疗自身免疫性疾病理论探讨[J].时珍国医国药,2017,28(1):225-226.
[10] 智宇星,李红梅,徐安龙.中西医学视角下对免疫的再认识——基于辨证论治和免疫态的讨论[J].中医杂志,2022,63(21):2001-2008.
[11] 曹继刚,任梅荣,赵敏.先天肾虚与免疫的联系及其中医对策[J].时珍国医国药,2021,32(1):143-145.
[12] 胡骏,谈钰濛,滕飞,等.“相火”与干细胞相关关系的探讨[J].江苏中医药,2017,49(12):25-28.
[13] 赵昌林.肝主疏泄为调控免疫功能的核心[J].中医杂志,2017,58(7):568-571.
[14] 龚建萍,李倩,赵述芳,等.免疫因素在溃疡性结肠炎发病机制中的研究进展[J].现代消化及介入诊疗,2020,25(12):1676-1679.
[15] 邓怀涵.陈潮祖教授“膜腠三焦”学术思想及临证运用研究[D].成都:成都中医药大学,2019.
[16] 刘静,韦美岐,李平,等.基于黏膜免疫的中医药治疗溃疡性结肠炎机制研究进展[J].环球中医药,2022,15(5):895-901.
[17] 郭琳,王雅婷,考延磊,等.闫雪洁运用寒热并用法治疗溃疡性结肠炎经验[J].陕西中医,2020,41(8):1148-1151.
[18] 程敬,吕尚斌,张怡,等.温肾健脾法治疗缓解期溃疡性结肠炎的研究进展[J].中华中医药杂志,2022,37(2):927-932.
[19] 盛天骄,巩阳,李娜,等.“温清共用法”治疗溃疡性结肠炎的疗效观察及作用机制探讨[J].中国中西医结合消化杂志,2022,30(12):849-853.
[20] 刘忻颖,陈胜良.精神心理因素在溃疡性结肠炎中作用的研究进展[J].胃肠病学,2018,23(3):173-176.
[21] 敬秀平,宋小平,刘珊.加味白头翁汤灌肠治疗慢性溃疡性结肠炎临床研究[J].陕西中医,2021,42(8):1060-1063.
[22] 陈士铎.本草新编[M].太原:山西科学技术出版社,2011:132.
[23] 张波,惠永峰,李海玲,等.益脾祛湿理肠汤治疗溃疡性结肠炎疗效及对患者肠黏膜屏障功能的影响[J].陕西中医,2021,42(8):1024-1027.
[24] 梁国英,金宏莹,蔡宏波.谢晶日相火论治溃疡性结肠炎经验浅析[J].辽宁中医杂志,2022,49(8):39-41.
[25] 邹林焘,邹正华,杜学芳.清肠解毒汤治疗溃疡性结肠炎湿热内蕴证临床研究[J].陕西中医,2021,42(5):597-600.

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金资助项目(81874466); 全国名老中医药专家传承工作室建设项目[国中医药人教函(2022)75号]; 国家重点研发计划(2017YFC1700601); 湖南省研究生科研创新项目(2022CX159)
更新日期/Last Update: 2024-02-07